Synthesis of 2,5- and 3,5-diphenylpyridine derivatives for DNA recognition and cytotoxicity

European Journal of Medicinal Chemistry

Volumn 40, Issue 11, 2005, Pages 1087-1095

  Jacquemard, Ulrich ^d   Routier, Sylvain ^a   Dias, Nathalie ^b   Lansiaux, Amélie ^b   Goossens, Jean François ^c   Bailly, Christian ^b   Mérour, Jean Yves ^a  

^a UNIVERSITÉ D'ORLÉANS   (France)

^b INSERM   (France)

^c UNIV LILLE   (France)

^d NONE

Author keywords

Binding; Cycle cell analysis; Cytotoxicity; DNA; Pyridine

Indexed keywords

2,5 BIS(4 HYDROXYPHENYL)PYRIDINE; 2,5 BIS[4 (2 DIMETHYLAMINOETHOXY)PHENYL]PYRIDIN 3 YLPHENOXYETHYLDIMETHYLAMINE; 2,5 BIS[4 (2 HYDROXYETHOXY)PHENYL]PYRIDINE; 2,5 BIS[4 (3 DIMETHYLAMINOPROPOXY)PHENYL]PYRIDINE; 3,5 BIS(3 HYDROXYPHENYL)PYRIDINE; 3,5 BIS(4 HYDROXYPHENYL)PYRIDINE; 3,5 BIS[3 (2 DIMETHYLAMINOETHOXY)PHENYL]PYRIDINE; 3,5 BIS[3 (2 HYDROXYETHOXY)PHENYL]PYRIDINE; 3,5 BIS[3 (3 DIMETHYLAMINOPROPOXY)PHENYL]PYRIDINE; 3,5 BIS[4 (2 DIMETHYLAMINOETHOXY)PHENYL]PYRIDINE; 3,5 BIS[4 (2 HYDROXYETHOXY)PHENYL]PYRIDINE; 3,5 BIS[4 (3 DIMETHYLAMINOPROPOXY)PHENYL]PYRIDINE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CORRELATION ANALYSIS; CYTOTOXICITY; DNA BINDING; DRUG ACTIVITY; DRUG DNA BINDING; DRUG DNA INTERACTION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STATISTICAL SIGNIFICANCE;

DNA; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INTERCALATING AGENTS; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 26844441554     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2005.04.011     Document Type: Article

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