In vitro induction of polyploidy and chromatid exchanges by culture medium extracts of natural rubbers compounded with 2-mercaptobenzothiazole as a positive control candidate for genotoxicity tests

Journal of Biomedical Materials Research - Part A

Volumn 75, Issue 2, 2005, Pages 439-444

  Matsuoka, Atsuko ^a   Isama, Kazuo ^a   Tsuchiya, Toshie ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Chromosome aberrations; Cytotoxicity; Endoreduplication; Natural rubber; Zinc dibutyldithiocarbamate

Indexed keywords

CELL CULTURE; CHROMOSOMES; MEDICAL APPLICATIONS; METABOLISM; TOXICITY; ZINC COMPOUNDS;

CHROMOSOME ABERRATION; CYTOTOXICITY; ENDOREDUPLICATION; ZINC DIBUTYLDITHIOCARBAMATE;

RUBBER;

2 MERCAPTOBENZOTHIAZOLE; DITHIOCARBAMIC ACID DERIVATIVE; NATURAL PRODUCT; PROMUTAGEN; RUBBER; UNCLASSIFIED DRUG; ZINC; ZINC DIBUTYLDITHIOCARBAMIC ACID;

ANIMAL CELL; ARTICLE; BIOMEDICAL TECHNOLOGY ASSESSMENT; BIOSAFETY; CELL STRAIN; CELL STRAIN CHL; CELL STRAIN V 79; CHROMATID EXCHANGE; CHROMOSOME ABERRATION; COLONY FORMATION; CONTROL; CULTURE MEDIUM; CYTOTOXICITY; DEVICE; ENDOREDUPLICATION; EXTRACT; GENOTOXICITY; IN VITRO STUDY; MEDICAL DEVICE; METABOLIC ACTIVATION; NONHUMAN; POLYPLOIDY; TOXICITY TESTING;

ANIMALS; ANTIFUNGAL AGENTS; BENZOTHIAZOLES; CELL LINE; CHROMOSOME ABERRATIONS; CULTURE MEDIA; JAPAN; MATERIALS TESTING; MUTAGENICITY TESTS; POLYPLOIDY; RATS; RATS, SPRAGUE-DAWLEY; RUBBER; SISTER CHROMATID EXCHANGE; THIAZOLES;

EID: 26844433013     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.a.30442     Document Type: Article

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