Effects of chronic ethanol (EtOH) administration on pro-inflammatory cytokines of the hypothalamic-pituitary-gonadal (HPG) axis in female rats

Endocrine Research

Volumn 31, Issue 1, 2005, Pages 9-16

  Emanuele, Nicholas ^a   LaPaglia, Nancy ^a   Kovacs, Elizabeth J ^b   Emanuele, Mary Ann ^a,c  

^a VA Hospital   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Ethanol; Gonad; Hypothalamus; IL 6; Pituitary; TNF

Indexed keywords

ALCOHOL; CYTOKINE; INTERLEUKIN 6; MALTOSE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DIET; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GONAD; HYPOPHYSIS; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; NONHUMAN; OVARY; PRIORITY JOURNAL; RAT; REPRODUCTION;

ANIMALS; ETHANOL; FEMALE; GONADS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; HYPOTHALAMUS; INTERLEUKIN-6; OVARY; PITUITARY GLAND; RATS; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 26444591605     PISSN: 07435800     EISSN: 15324206     Source Type: Journal    
DOI: 10.1080/07435800500228930     Document Type: Article

References (42)

1. Emanuele MA, Emanuele NV. Alcohol's effects on female reproductive function. Alc Health Res World 2002; 26: 274-281.
2. Emanuele MA, Emanuele NV. Alcohol and the male reproductive system. Alc Health Res World 2001; 25:282-287.
3. Emanuele MA, LaPaglia N, Steiner J, Kirsteins L, Emanuele NV. Effects of nitric oxide synthase blockade on the acute response of the reproductive axis to ethanol in pubertal male rats. Alcohol: Clin Exp Res 1999; 23:870-877.
4. Emanuele NV, LaPaglia N, Steiner J, Kirsteins L, Emanuele MA. Reversal of chronic ethanol-induced testosterone suppression in peripubertal male rats by opiate blockade. Alcohol: Clin Exp Res 1999; 23:60-66.
5. Adams ML, Meyer ER, Cicero TJ. Interactions between alcohol and opioid-induced suppression of rat testicular steroidogenesis in vivo. Alcohol: Clin Exp Res 1997; 21:684-690.
6. Adams ML, Meyer ER, Cicero TH. Effects of nitric oxide-related agents on opioid regulation of rat testicular steroidogenesis. Biol Reprod 1996; 54:1128-1134.
7. Adams ML, Meyer ER, Sewing BN, Cicero TJ. Effects of nitric oxide-related agents on rat testicular function. J Pharmacol Exp Ther 1994; 269:230-237.
8. Qin Shi, Hales DB, Emanuele NV, Emanuele MA. Interaction of ethanol and nitric oxide in the hypothalamic-pituitary-gonadal axis in the male rat. Alcohol Clin Exp Res 1998; 22:1754-1762.
9. Qin Shi, Emanuele NV, Emanuele MA. Effect of nitric oxide synthase inhibitors on preventing ethanol-induced suppression of the hypothalamic- pituitary-gonadal axis in the male rat. Alcohol Clin Exp Res 1998; 22:1763-1770.
10. Qin Shi, LaPaglia N, Emanuele NV, Emanuele MA. Castration differentially regulates nitric oxide synthase in the hypothalamus and pituitary. Endocr Res 1998; 24:29-54.
11. Zhu QL, Meisinger J, Emanuele NV, Emanuele MA, Fortuno F, Van Thiel DH. Ethanol exposure enhances apoptosis within the testes. Alcohol Clin Exp Res 2000; 24:1550-1556.
12. Steiner JC, LaPaglia N, Hansen M, Emanuele NV, Emanuele MA. Effect of chronic ethanol on reproductive and growth hormone in the peripubertal male rat. J Endocrinol 1997; 154:363-370.
13. Colantoni A, Idilman R, DeMaria N, LaPaglia N, Belmonte J, Wezeman F, Emanuele N, Van Thiel DH, Kovacs EJ, Emanuele MA. Hepatic apoptosis and proliferation in male and female rats fed alcohol: role of cytokines. Alcohol Clin Exp Res 2003; 27:1184-1189.
14. Emanuele NV, LaPaglia N, Steiner J, Ren J, Emanuele MA. EtOH disrupts female mammalian puberty: age and opiate dependence. Endocrine 2002; 18:247-254.
15. Emanuele NV, LaPaglia N, Steiner J, Kirsteins L, Emanuele MA. The effect of chronic EtOH exposure on female rat reproductive cyclicity, hormone secretion and gene expression. Alcohol Clin Exp Res 2001; 25:1025-1029.
16. LaPaglia N, Steiner J, Kirsteins L, Emanuele MA, Emanuele N. The impact of acute ethanol on reproductive hormone synthesis, processing, and secretion in female rats at proestrous. Alcohol Clin Exp Res 1997; 21:1567-1572.
17. Ching M, Valenca M, Negro-Vilar A. Acute EtOH treatment lowers hypophyseal portal plasma LHRH and systemic LH levels in rats. Brain Res 1994; 443:325-328.
18. Ogilvie KM, Rivier C. Effect of alcohol on the proestrous surge of luteinizing hormone (LH) and the activation of LH-releasing (LHRH) neurons in the female rat. J Neuroscience 1997; 17:2595-2604.
19. Risz NM, Joost HG, Eckel J. Increased hypothalamic expression of the P75 tumor necrosis factor receptor in New Zealand obese mice. Horm Metabol Res 2001; 33:520-524.
20. Goujon E, Parnet P, Laye S, Combe C, Dantzer R. Adrenalectomy enhances pro-inflammatory cytokines gene expression in the spleen, pituitary and brain of mice in response to lipopolysaccharide. Brain Res: Mol Brain Res 1996; 36:53-62.
21. Goujon E, Parnet P, Laye S, Combe C, Kelley KW, Dantzer R. Stress down regulates lipopolysaccharide-induced expression of pro-inflammatory cytokines in the spleen, pituitary, and brain of mice. Brain, Behavior & Immunity 1995; 9:292-303.
22. Laye S, Parnet P, Goujon E, Dantzer R. Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice. Brain Res: Mol Brain Res 1994; 27:157-162.
23. Yoo MJ, Nishihara M, Takahashi M. Tumor necrosis factor-alpha mediates endotoxin induced suppression of gonadotropin-releasing hormone pulse generator activity in the rat. Endocrine J 1997; 44:141-148.
24. Russell SH, Small CJ, Stanley SA, Franks S, Ghatei MA, Bloom SR. The in vitro role of tumor necrosis factor-alpha and interleukin-6 in the hypothalamic-pituitary-gonadal axis. J Neuroendocrinol 2001; 13:296-301.
25. Yamaguchi M, Koike K, Yoshimoto Y, Matsuzaki N, Miyake A, Tanizawa O. Interleukin-6 stimulates gonadotropin-releasing hormone secretion for rat hypothalamic cells. Hormone Res 1991; 35:252-256.
26. Yamaguchi M, Yoshimoto Y, Komura H, Koike K, Matsuzaki N, Hirota K, Miyake A, Tanizawa O. Interleukin 1 beta and tumor necrosis factor alpha stimulate release of gonadotropin-releasing hormone and interleukins 6 by primary cultured rat hypothalamic cells. Acta Endocrinol 1990; 123:476-480.
27. Feleder C, Wuttke W, Moguilevsky JA. Hypothalamic relationships between interleukins-6 and LHRH release affected by bacterial endotoxin in adult male rats: involvement of the inhibitory amino acid system. Biol Sig Recept 1998; 7:7-14.
28. Theas S, De Laurentiis A, Candolfi M, Lopez SL, Carrasco AE, Zaldivar V, Seilcovich A. Nitric oxide mediates the inhibitory effect of tumor necrosis factor-alpha on prolactin release. Neuroendocrinol 2001; 74:82-86.
29. Rivier C. Effect of acute alcohol treatment on the release of ACTH, corticosterone, and proinflammatory cytokines in response to endotoxin. Alcohol: Clin Exp Res 1999; 23:473-682.
30. Nadeau S, Rivest S. Regulation of the gene encoding tumor necrosis factor alpha (TNFα) in rat brain and pituitary in response in different models of systemic immune challenge. J Neuropath Exp Neuro 1999; 58:61-77.
31. Kobayashi H, Fukata J, Murakami N, Usui T, Ebisui O, Muro S, Hanaoka I, Inoue K, Imura H, Nakao K. Tumor necrosis factor receptors in the pituitary cells. Brain Res 1997; 758:45-50.
32. Arras M, Hoche A, Bohle R, Eckert P, Riedel W, Schaper J. Tumor necrosis factor-alpha in macrophages of heart, liver, kidney, and in the pituitary gland. Cell & Tissue Res 1996; 285:39-49.
33. Wolvers DA, Marquette C, Berkenbosch F, Haour F. Tumor necrosis factor-alpha: specific binding sites in rodent brain and pituitary gland. European Cytokine Network 1993; 4:377-381.
34. Elsasser TH, Caperna TJ, Fayer R. Tumor necrosis factor-alpha affects growth hormone secretion by a direct pituitary interaction. Pro Soc Exp Bio Med 1991; 198:547-554.
35. Gaillard RC, Turnill D, Sappino P, Muller AF. Tumor necrosis factor-alpha inhibits the hormonal response of the pituitary gland to hypothalamic releasing factors. Endocrinology 1990; 127:101-106.
36. Terranova PF, Rice VM. Review: cytokine involvement in ovarian processes. American J Reprod Immuno 1997; 37:50-63.
37. Terranova PF, Hunter VJ, Roby KF, Hunt JS. Tumor necrosis factor-alpha in the female reproductive tract. Proc Sox Exp Bio Med 1995; 209:325-342.
38. Marcinkiewicz JL, Balchak SK, Morrison LJ. The involvement of tumor necrosis factor-alpha (TNF) as an intraovarian regulator of oocyte apoptosis in the neonatal rat. Fronters Bioscience 2002; 7:d1997-2005.
39. Tamura K, Kawaguchi T, Kogo H. Interleukin-6 inhibits the expression of luteinizing hormone receptor mRNA during the maturation of cultured rat granulose cells. J Endocrinol 2001; 170:121-127.
40. Salmassi A, Lu S, Hedderich J, Oettinghaus C, Jonat W, Mettler L. Interaction of interleukin-6 on human granulose cell steroid secretion. J Endocrinol 2001; 170:471-478.
41. Tamura K, Kawaguchi T, Hara T, Takatoshi S, Tohei A, Miyajima A, Seishi T, Kogo H. Interleukin-6 decreases estrogen production and messenger ribonucleic acid expression encoding aromatase during in vitro cytodifferentiation of rat granulose cell. Mol Cell Endocrin 2000; 170:103-111.
42. Van der Hoek KH, Woodhouse CM, Brannstrom M, Norman RJ. Effects of interleukin (IL)-6 on luteinizing hormone and IL-1 beta-induced ovulation and steroidogenesis in the rat ovary. Bio Repro 1998; 58:1266-1271.