Methylene blue is more toxic to erythroleukemic cells than to normal peripheral blood mononuclear cells: A possible use in chemotherapy

Cancer Chemotherapy and Pharmacology

Volumn 56, Issue 6, 2005, Pages 659-665

  Kirszberg, C ^a   Rumjanek, V M ^a   Capella, M A M ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Erythroleukemia; Methylene blue; Multidrug resistance; Peripheral blood lymphocytes; Reactive oxygen species

Indexed keywords

ANTINEOPLASTIC AGENT; DIHYDRORHODAMINE 123; DNA; FREE RADICAL; HYDROGEN PEROXIDE; LIPOCORTIN 5; METHYLENE BLUE; PHYTOHEMAGGLUTININ; PROPIDIUM IODIDE; RHODAMINE; THYMIDINE; TRITIUM; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CELL DEATH; CELL LINEAGE; CELL PROLIFERATION; COLORIMETRY; CONTROLLED STUDY; CYTOMETRY; CYTOTOXICITY; DRUG EFFECT; DRUG SENSITIVITY; DRUG UPTAKE; ERYTHROLEUKEMIA CELL; FLUORESCENCE; HUMAN; HUMAN CELL; LYMPHOCYTE; MEASUREMENT; MELANOCYTE; MELANOMA; NITROBLUE TETRAZOLIUM TEST; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PHOTOSENSITIZATION; PRIORITY JOURNAL; RADIOSENSITIZATION; TUMOR CELL;

ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; CELL SURVIVAL; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; FLOW CYTOMETRY; HUMANS; HYDROGEN PEROXIDE; K562 CELLS; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTES; MELANOCYTES; METHYLENE BLUE; PHYTOHEMAGGLUTININS;

EID: 26444575934     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-005-1014-3     Document Type: Article

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