-
1
-
-
0037379794
-
ERK(-MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK)
-
Aguirre-Ghiso JA, Estrada Y, Liu D, Ossowski L (2003) ERK(-MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK). Cancer Res 63:1684-1695
-
(2003)
Cancer Res
, vol.63
, pp. 1684-1695
-
-
Aguirre-Ghiso, J.A.1
Estrada, Y.2
Liu, D.3
Ossowski, L.4
-
2
-
-
0035418622
-
Activated extracellular signal-regulated kinases: Association with epidermal growth factor receptor/transforming growth factor alpha expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatments
-
Albanell J, Codony-Servat J, Rojo F, Del Campo JM, Sauleda S, Anido J, Raspall G, Giralt J, Rosello J, Nicholson RI, Mendelsohn J, Baselga J (2001) Activated extracellular signal-regulated kinases: association with epidermal growth factor receptor/transforming growth factor alpha expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatments. Cancer Res 61:6500-6510
-
(2001)
Cancer Res
, vol.61
, pp. 6500-6510
-
-
Albanell, J.1
Codony-Servat, J.2
Rojo, F.3
Del Campo, J.M.4
Sauleda, S.5
Anido, J.6
Raspall, G.7
Giralt, J.8
Rosello, J.9
Nicholson, R.I.10
Mendelsohn, J.11
Baselga, J.12
-
3
-
-
3042531148
-
Persistent activation of the Akt pathway in head and neck squamous cell carcinoma: A potential target for UCN-01
-
Amornphimoltham P, Sriuranpong V, Patel V, Benavides F, Conti CJ, Sauk J, Sausville EA, Molinolo AA, Gutkind JS (2004) Persistent activation of the Akt pathway in head and neck squamous cell carcinoma: a potential target for UCN-01. Clin Cancer Res 10:4029-4037
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4029-4037
-
-
Amornphimoltham, P.1
Sriuranpong, V.2
Patel, V.3
Benavides, F.4
Conti, C.J.5
Sauk, J.6
Sausville, E.A.7
Molinolo, A.A.8
Gutkind, J.S.9
-
4
-
-
0032980723
-
The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells
-
Bost F, McKay R, Bost M, Potapova O, Dean NM, Mercola D (1999) The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells. Mol Cell Biol 19:1938-1949
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1938-1949
-
-
Bost, F.1
McKay, R.2
Bost, M.3
Potapova, O.4
Dean, N.M.5
Mercola, D.6
-
5
-
-
0024851765
-
New malignancy grading is a better prognostic indicator than Broders' grading in oral squamous cell carcinomas
-
Bryne M, Koppang HS, Lilleng R, Stene T, Bang G, Dabelsteen E (1989) New malignancy grading is a better prognostic indicator than Broders' grading in oral squamous cell carcinomas. J Oral Pathol Med 18:432-437
-
(1989)
J Oral Pathol Med
, vol.18
, pp. 432-437
-
-
Bryne, M.1
Koppang, H.S.2
Lilleng, R.3
Stene, T.4
Bang, G.5
Dabelsteen, E.6
-
6
-
-
0041733629
-
Prognostic significance of EGFR and Her-2 in oral cavity cancer in betel quid prevalent area cancer prognosis
-
Chen IH, Chang JT, Liao CT, Wang HM, Hsieh LL, Cheng AJ (2003) Prognostic significance of EGFR and Her-2 in oral cavity cancer in betel quid prevalent area cancer prognosis. Br J Cancer 89:681-686
-
(2003)
Br J Cancer
, vol.89
, pp. 681-686
-
-
Chen, I.H.1
Chang, J.T.2
Liao, C.T.3
Wang, H.M.4
Hsieh, L.L.5
Cheng, A.J.6
-
7
-
-
0041940129
-
Implication of protein kinase B/Akt and Bcl-2/Bcl-XL suppression by the farnesyl transferase inhibitor SCH66336 in apoptosis induction in squamous carcinoma cells
-
Chun KH, Lee HY, Hassan K, Khuri F, Hong WK, Lotan R (2003) Implication of protein kinase B/Akt and Bcl-2/Bcl-XL suppression by the farnesyl transferase inhibitor SCH66336 in apoptosis induction in squamous carcinoma cells. Cancer Res 63:4796-4800
-
(2003)
Cancer Res
, vol.63
, pp. 4796-4800
-
-
Chun, K.H.1
Lee, H.Y.2
Hassan, K.3
Khuri, F.4
Hong, W.K.5
Lotan, R.6
-
8
-
-
0036668768
-
Subcellular localization of beta-catenin in malignant cell lines and squamous cell carcinomas of the oral cavity
-
Gasparoni A, Chaves A, Fonzi L, Johnson GK, Schneider GB, Squier CA (2002) Subcellular localization of beta-catenin in malignant cell lines and squamous cell carcinomas of the oral cavity. J Oral Pathol Med 31:385-394
-
(2002)
J Oral Pathol Med
, vol.31
, pp. 385-394
-
-
Gasparoni, A.1
Chaves, A.2
Fonzi, L.3
Johnson, G.K.4
Schneider, G.B.5
Squier, C.A.6
-
9
-
-
0027350726
-
TGF-alpha and EGFR in head and neck cancer
-
Grandis JR, Tweardy DJ (1993) TGF-alpha and EGFR in head and neck cancer. J Cell Biochem Suppl 17F:188-191
-
(1993)
J Cell Biochem Suppl
, vol.17 F
, pp. 188-191
-
-
Grandis, J.R.1
Tweardy, D.J.2
-
10
-
-
0037728809
-
The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines
-
Grille SJ, Bellacosa A, Upson J, Klein-Szanto AJ, van Roy F, Lee-Kwon W, Donowitz M, Tsichlis PN, Larue L (2003) The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. Cancer Res 63:2172-2178
-
(2003)
Cancer Res
, vol.63
, pp. 2172-2178
-
-
Grille, S.J.1
Bellacosa, A.2
Upson, J.3
Klein-Szanto, A.J.4
Van Roy, F.5
Lee-Kwon, W.6
Donowitz, M.7
Tsichlis, P.N.8
Larue, L.9
-
11
-
-
0037228832
-
Increased expression of epidermal growth factor receptor induces sequestration of extracellular signal-related kinases and selective attenuation of specific epidermal growth factor-mediated signal transduction pathways
-
Habib AA, Chun SJ, Neel BG, Vartanian T (2003) Increased expression of epidermal growth factor receptor induces sequestration of extracellular signal-related kinases and selective attenuation of specific epidermal growth factor-mediated signal transduction pathways. Mol Cancer Res 1:219-233
-
(2003)
Mol Cancer Res
, vol.1
, pp. 219-233
-
-
Habib, A.A.1
Chun, S.J.2
Neel, B.G.3
Vartanian, T.4
-
12
-
-
0036055766
-
Correlation between laminin-5 gamma2 chain expression and epidermal growth factor receptor expression and its clinicopathological significance in squamous cell carcinoma of the tongue
-
Katoh K, Nakanishi Y, Akimoto S, Yoshimura K, Takagi M, Sakamoto M, Hirohashi S (2002) Correlation between laminin-5 gamma2 chain expression and epidermal growth factor receptor expression and its clinicopathological significance in squamous cell carcinoma of the tongue. Oncology 62:318-326
-
(2002)
Oncology
, vol.62
, pp. 318-326
-
-
Katoh, K.1
Nakanishi, Y.2
Akimoto, S.3
Yoshimura, K.4
Takagi, M.5
Sakamoto, M.6
Hirohashi, S.7
-
13
-
-
0029974391
-
Further evidence for prognostic significance of epidermal growth factor receptor gene amplification in patients with esophageal squamous cell carcinoma
-
Kitagawa Y, Ueda M, Ando N, Ozawa S, Shimizu N, Kitajima M (1996) Further evidence for prognostic significance of epidermal growth factor receptor gene amplification in patients with esophageal squamous cell carcinoma. Clin Cancer Res 2:909-914
-
(1996)
Clin Cancer Res
, vol.2
, pp. 909-914
-
-
Kitagawa, Y.1
Ueda, M.2
Ando, N.3
Ozawa, S.4
Shimizu, N.5
Kitajima, M.6
-
14
-
-
0033992633
-
Biochemical and clinical implications of the ErbB/HER signaling network of growth factor receptors
-
Klapper LN, Kirschbaum MH, Sela M, Yarden Y (2000) Biochemical and clinical implications of the ErbB/HER signaling network of growth factor receptors. Adv Cancer Res 77:25-79
-
(2000)
Adv Cancer Res
, vol.77
, pp. 25-79
-
-
Klapper, L.N.1
Kirschbaum, M.H.2
Sela, M.3
Yarden, Y.4
-
15
-
-
0036792220
-
Multiple mitogenic pathways in pancreatic cancer cells are blocked by a truncated epidermal growth factor receptor
-
Matsuda K, Idezawa T, You XJ, Kothari NH, Fan H, Korc M (2002) Multiple mitogenic pathways in pancreatic cancer cells are blocked by a truncated epidermal growth factor receptor. Cancer Res 62:5611-5617
-
(2002)
Cancer Res
, vol.62
, pp. 5611-5617
-
-
Matsuda, K.1
Idezawa, T.2
You, X.J.3
Kothari, N.H.4
Fan, H.5
Korc, M.6
-
16
-
-
0036314050
-
Overexpression of extracellular-signal regulated kinases on oral squamous cell carcinoma
-
Mishima K, Inoue K, Hayashi Y (2002) Overexpression of extracellular-signal regulated kinases on oral squamous cell carcinoma. Oral Oncol 38:468-474
-
(2002)
Oral Oncol
, vol.38
, pp. 468-474
-
-
Mishima, K.1
Inoue, K.2
Hayashi, Y.3
-
17
-
-
4043115618
-
Calcium induced matrix metalloproteinase 9 gene expression is differentially regulated by ERK1/2 and p38 MAPK in oral keratinocytes and oral squamous cell carcinoma
-
Mukhopadhyay S, Munshi HG, Kambhampati S, Sassano A, Platanias LC, Stack MS (2004) Calcium induced matrix metalloproteinase 9 gene expression is differentially regulated by ERK1/2 and p38 MAPK in oral keratinocytes and oral squamous cell carcinoma. J Biol Chem 279(32):33139-33146
-
(2004)
J Biol Chem
, vol.279
, Issue.32
, pp. 33139-33146
-
-
Mukhopadhyay, S.1
Munshi, H.G.2
Kambhampati, S.3
Sassano, A.4
Platanias, L.C.5
Stack, M.S.6
-
18
-
-
4644356493
-
Differential regulation of membrane-type 1 matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls TGF-beta1-induced pericellular collagenolysis
-
Munshi HG, Wu YI, Mukhopadhyay S, Ottaviano AJ, Sassano A, Koblinski JE, Platanias LC, Stack MS (2004) Differential regulation of membrane-type 1 matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls TGF-beta1-induced pericellular collagenolysis. J Biol Chem 279(37):39042-39050
-
(2004)
J Biol Chem
, vol.279
, Issue.37
, pp. 39042-39050
-
-
Munshi, H.G.1
Wu, Y.I.2
Mukhopadhyay, S.3
Ottaviano, A.J.4
Sassano, A.5
Koblinski, J.E.6
Platanias, L.C.7
Stack, M.S.8
-
19
-
-
0035892777
-
High expression levels of nuclear factor kappaB, IkappaB kinase alpha and Akt kinase in squamous cell carcinoma of the oral cavity
-
Nakayama H, Ikebe T, Beppu M, Shirasuna K (2001) High expression levels of nuclear factor kappaB, IkappaB kinase alpha and Akt kinase in squamous cell carcinoma of the oral cavity. Cancer 92:3037-3044
-
(2001)
Cancer
, vol.92
, pp. 3037-3044
-
-
Nakayama, H.1
Ikebe, T.2
Beppu, M.3
Shirasuna, K.4
-
20
-
-
0037168957
-
Epidermal growth factor receptor gene amplification is correlated with laminin-5 gamma2 chain expression in oral squamous cell carcinoma cell lines
-
Ono Y, Nakanishi Y, Gotoh M, Sakamoto M, Hirohashi S (2002) Epidermal growth factor receptor gene amplification is correlated with laminin-5 gamma2 chain expression in oral squamous cell carcinoma cell lines. Cancer Lett 175:197-204
-
(2002)
Cancer Lett
, vol.175
, pp. 197-204
-
-
Ono, Y.1
Nakanishi, Y.2
Gotoh, M.3
Sakamoto, M.4
Hirohashi, S.5
-
21
-
-
13844273087
-
PI3K-Akt pathway: Its functions and alterations in human cancer
-
Osaki M, Oshimura M, Ito H (2004) PI3K-Akt pathway: its functions and alterations in human cancer. Apoptosis 9:667-676
-
(2004)
Apoptosis
, vol.9
, pp. 667-676
-
-
Osaki, M.1
Oshimura, M.2
Ito, H.3
-
22
-
-
0034992521
-
The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification
-
Prenzel N, Fischer OM, Streit S, Hart S, Ullrich A (2001) The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr Relat Cancer 8:11-31
-
(2001)
Endocr Relat Cancer
, vol.8
, pp. 11-31
-
-
Prenzel, N.1
Fischer, O.M.2
Streit, S.3
Hart, S.4
Ullrich, A.5
-
23
-
-
0036523704
-
The invasive phenotype in HMT-3522 cells requires increased EGF receptor signaling through both PI 3-kinase and ERK 1,2 pathways
-
Price DJ, Avraham S, Feuerstein J, Fu Y, Avraham HK (2002) The invasive phenotype in HMT-3522 cells requires increased EGF receptor signaling through both PI 3-kinase and ERK 1,2 pathways. Cell Commun Adhes 9:87-102
-
(2002)
Cell Commun Adhes
, vol.9
, pp. 87-102
-
-
Price, D.J.1
Avraham, S.2
Feuerstein, J.3
Fu, Y.4
Avraham, H.K.5
-
24
-
-
0033607784
-
Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt
-
Rommel C, Clarke BA, Zimmermann S, Nunez L, Rossman R, Reid K, Moelling K, Yancopoulos GD, Glass DJ (1999) Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. Science 286:1738-1741
-
(1999)
Science
, vol.286
, pp. 1738-1741
-
-
Rommel, C.1
Clarke, B.A.2
Zimmermann, S.3
Nunez, L.4
Rossman, R.5
Reid, K.6
Moelling, K.7
Yancopoulos, G.D.8
Glass, D.J.9
-
25
-
-
0037267499
-
Invasive front grading: Reliability and usefulness in the management of oral squamous cell carcinoma
-
Sawair FA, Irwin CR, Gordon DJ, Leonard AG, Stephenson M, Napier SS (2003) Invasive front grading: reliability and usefulness in the management of oral squamous cell carcinoma. J Oral Pathol Med 32:1-9
-
(2003)
J Oral Pathol Med
, vol.32
, pp. 1-9
-
-
Sawair, F.A.1
Irwin, C.R.2
Gordon, D.J.3
Leonard, A.G.4
Stephenson, M.5
Napier, S.S.6
-
26
-
-
0037437146
-
Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution
-
Schenk S, Hintermann E, Bilban M, Koshikawa N, Hojilla C, Khokha R, Quaranta V (2003) Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution. J Cell Biol 161:197-209
-
(2003)
J Cell Biol
, vol.161
, pp. 197-209
-
-
Schenk, S.1
Hintermann, E.2
Bilban, M.3
Koshikawa, N.4
Hojilla, C.5
Khokha, R.6
Quaranta, V.7
-
27
-
-
0037012011
-
Functional roles of Akt signaling in mouse skin tumorigenesis
-
Segrelles C, Ruiz S, Perez P, Murga C, Santos M, Budunova IV, Martinez J, Larcher F, Slaga TJ, Gutkind JS, Jorcano JL, Paramio JM (2002) Functional roles of Akt signaling in mouse skin tumorigenesis. Oncogene 21:53-64
-
(2002)
Oncogene
, vol.21
, pp. 53-64
-
-
Segrelles, C.1
Ruiz, S.2
Perez, P.3
Murga, C.4
Santos, M.5
Budunova, I.V.6
Martinez, J.7
Larcher, F.8
Slaga, T.J.9
Gutkind, J.S.10
Jorcano, J.L.11
Paramio, J.M.12
-
28
-
-
0036234820
-
p38 MAP kinase mediates platelet-derived growth factor-stimulated migration of hepatic myofibroblasts
-
Tangkijvanich P, Santiskulvong C, Melton AC, Rozengurt E, Yee HF Jr (2002) p38 MAP kinase mediates platelet-derived growth factor-stimulated migration of hepatic myofibroblasts. J Cell Physiol 191:351-361
-
(2002)
J Cell Physiol
, vol.191
, pp. 351-361
-
-
Tangkijvanich, P.1
Santiskulvong, C.2
Melton, A.C.3
Rozengurt, E.4
Yee Jr., H.F.5
-
29
-
-
0035949699
-
AKT plays a central role in tumorigenesis
-
U S A
-
Testa JR, Bellacosa A (2001) AKT plays a central role in tumorigenesis. Proc Natl Acad Sci U S A 98:10983-10985
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 10983-10985
-
-
Testa, J.R.1
Bellacosa, A.2
-
30
-
-
1842529307
-
Ligand-induced, p38-dependent apoptosis in cells expressing high levels of epidermal growth factor receptor and ErbB-2
-
Tikhomirov O, Carpenter G (2004) Ligand-induced, p38-dependent apoptosis in cells expressing high levels of epidermal growth factor receptor and ErbB-2. J Biol Chem 279:12988-12996
-
(2004)
J Biol Chem
, vol.279
, pp. 12988-12996
-
-
Tikhomirov, O.1
Carpenter, G.2
-
31
-
-
0038521319
-
Mammalian tolloid metalloproteinase, and not matrix metalloprotease 2 or membrane type 1 metalloprotease, processes laminin-5 in keratinocytes and skin
-
Veitch DP, Nokelainen P, McGowan KA, Nguyen TT, Nguyen NE, Stephenson R, Pappano WN, Keene DR, Spong SM, Greenspan DS, Findell PR, Marinkovich MP (2003) Mammalian tolloid metalloproteinase, and not matrix metalloprotease 2 or membrane type 1 metalloprotease, processes laminin-5 in keratinocytes and skin. J Biol Chem 278:15661-15668
-
(2003)
J Biol Chem
, vol.278
, pp. 15661-15668
-
-
Veitch, D.P.1
Nokelainen, P.2
McGowan, K.A.3
Nguyen, T.T.4
Nguyen, N.E.5
Stephenson, R.6
Pappano, W.N.7
Keene, D.R.8
Spong, S.M.9
Greenspan, D.S.10
Findell, P.R.11
Marinkovich, M.P.12
-
32
-
-
0034671479
-
Activation of fibroblast collagenase-1 expression by tumor cells of squamous cell carcinomas is mediated by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase-2
-
Westermarck J, Li S, Jaakkola P, Kallunki T, Grenman R, Kahari VM (2000) Activation of fibroblast collagenase-1 expression by tumor cells of squamous cell carcinomas is mediated by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase-2. Cancer Res 60:7156-7162
-
(2000)
Cancer Res
, vol.60
, pp. 7156-7162
-
-
Westermarck, J.1
Li, S.2
Jaakkola, P.3
Kallunki, T.4
Grenman, R.5
Kahari, V.M.6
|