Baohuoside-1 inhibits activated T cell proliferation at G1-S phase transition

Transplant Immunology

Volumn 15, Issue 1, 2005, Pages 55-62

  Ma, Anlun ^a   Qi, Shijie ^a   Xu, Dasheng ^a   Daloze, Pierre ^a   Chen, Huifang ^a,b  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b NOTRE DAME HOSPITAL   (Canada)

Author keywords

Baohuoside 1; Cell cycle; Immunosuppressant; Tacrolimus

Indexed keywords

BAOHUOSIDE 1; CYCLIN A; CYCLIN D; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2; CYCLINE; FLAVONOID; TACROLIMUS; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIAC GRAFT REJECTION; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; LYMPHOCYTE PROLIFERATION; MALE; NONHUMAN; PHASE TRANSITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; T LYMPHOCYTE; TUMOR CELL LINE; TUMOR GROWTH; WESTERN BLOTTING;

EID: 26444556981     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trim.2005.05.002     Document Type: Article

References (21)

1. B.D. Kahan Cyclosporin A, FK506, rapamycin: the use of a quantitative analytic tool to discriminate immunosuppressive drug interactions J Am Soc Nephrol 2 12 Suppl. 1992 S222
2. N.H. Sigal, and F.J. Dumont Cyclosporin A, FK506 and rapamycin: pharmacological probes of lymphocyted signal transduction Annu Rev Immunol 10 1992 519
3. S. Songia, A. Mortellaro, S. Taverna, C. Fornasiero, E.A. Scheiber, and E. Erba Characterization of the new immunosuppressive drug undecylprodigiosin in human lymphocytes: retinoblastoma protein, cyclin-dependent kinase-2, and cyclin-dependent kinase-4 as molecular targets J Immunol 158 1997 3987
4. H.R. Liang, P. Vuorela, H. Vuorela, and R. Hiltunen Isolation and immunomodulatory effect of flavonol glycosides from Epimedium hunanense Planta Med 63 4 1997 316
5. S.Y. Li, B.S. Teh, W.K. Seow, F. Li, and Y.H. Thong Effects of the plant flavonoid baohuoside-1 on cancer cell in vitro Cancer Lett 53 2-3 1990 175
6. S.Y. Li, G. Ping, L. Geng, W.K. Seow, and Y.H. Thong Immunopharmacology and toxicology of the plant flavonoid baohuoside-1 in mice Int J Immunopharmacol 16 3 1994 227
7. A. Ma, S. Qi, D. Xu, X. Zhang, and H. Chen Baohuoside-1, a novel immunosuppressive molecule, inhibits lymphocyte activation in vitro and in vivo Transplantation 78 6 2004 831
8. M.D. Vu, S. Qi, X. Wang, W. Jiang, A. Ma, and D. Xu Combination therapy of malononitrilamide FK778 with tacrolimus on cell proliferation assays and in rats receiving renal allografts Tansplantation 75 9 2003 1455
9. K. Mahalati, and B.D. Kahan Pharmacological surrogates of allograft outcome Ann Transplant 5 2 2000 14
10. A.A. Drosos Newer immunosuppressive drugs: their potential role in rheumatoid arthritis therapy Drugs 62 6 2002 891
11. J.C. Hong, and B.D. Kahan Immunosuppressive agents in organ transplantation: past, present, and future Semin Nephrol 20 2 2000 108
12. J. Liu, M.W. Albers, T.J. Wandless, S. Luan, D.G. Alberg, and P.J. Belshaw Schreiber. Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity Biochemistry 31 16 1992 3896
13. D.W. Shin, Z. Pan, A. Bandyopadhyay, M.B. Bhat, H. Kim do, and J. Ma Ca2+-dependent interaction between FKBP12 and calcineurin regulates activity of the Ca2+ release channel in skeletal muscle Biophys J 83 5 2002 2539
14. M.J. Barten, J.F. Gummert, T. van Gelder, R. Shorthouse, and R.E. Morris Flow cytometric quantitation of calcium-dependent and -independent mitogen stimulation of T cell functions in whole blood: inhibition by immunosuppressive drugs in vitro J Immunol Methods 253 1-2 2001 95
15. M. Pagano, R. Pepperkok, J. Lukas, V. Baldin, W. Ansorge, and J. Bartek Regulation of the cell cycle by the p33cdk2 protein kinase in cultured human fibroblasts J Cell Biol 121 1 1993 101
16. P. Clarke, and E. Karsenti Regulation of p34cdc2 protein kinase: new insights into protein phosphorylation and the cell cycle J Cell Sci 100 3 1991 409
17. C.T. Keith, and S.L. Schreiber PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints Science 270 5233 1995 50
18. C.J. Sherr D-type cyclins Trends Biochem Sci 20 5 1995 187
19. A. Koff, A. Giordano, D. Desai, K. Yamashita, J.W. Harper, and S. Elledge Formation and activation of a cyclin E-p33cdk2 complex during the G1 phase of the human cell cycle Science 257 5077 1992 1689
20. J.Y. Kato, M. Matsuoka, K. Polyak, J. Massague, and C.J. Sherr Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation Cell 79 3 1994 487
21. A.W. Thomson, and T.E. Starzl New immunosuppressive drugs: mechanistic insights and potential therapeutic advances Immunol Rev 136 1993 71