Dysfunction of erythropoietin-producing interstitial cells in the kidneys of ICR-derived glomerulonephritis (ICGN) mice

Journal of Veterinary Medical Science

Volumn 67, Issue 9, 2005, Pages 891-899

  Yamaguchi Yamada, Misuzu ^a   Manabe, Noboru ^b   Kiso, Minako ^a   Goto, Yasufumi ^a,b   Mori, Toshiharu ^a   Sakata, Chinatsu ^a   Anan, Sayuri ^a,b   Nagao, Masaya ^a   Yamamoto, Yoshie ^c   Ogura, Atsuo ^d  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^d RIKEN   (Japan)

Author keywords

Amplified in situ hybridization; Anemia with chronic renal disorder (CRD); Erythropoietin (EPO) producing cell; Hereditary nephrotic ICR derived glomerulpnephritis (ICGN) mouse; Kidney

Indexed keywords

ERYTHROPOIETIN; MESSENGER RNA;

ANALYSIS OF VARIANCE; ANEMIA; ANIMAL; ANOXIA; ARTICLE; CHRONIC KIDNEY FAILURE; COMPARATIVE STUDY; CYTOLOGY; GENETICS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INSTITUTE FOR CANCER RESEARCH MOUSE; KIDNEY; METABOLISM; MOUSE; PATHOPHYSIOLOGY;

ANALYSIS OF VARIANCE; ANEMIA; ANIMALS; ANOXIA; ERYTHROPOIETIN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KIDNEY; KIDNEY FAILURE, CHRONIC; MICE; MICE, INBRED ICR; RNA, MESSENGER;

EID: 26444539682     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.67.891     Document Type: Article

References (37)

1. Aukland, K. and Krog, J. 1960. Renal oxygen tension. Nature (Lond.) 188:671.
2. Bachmann, S., Le, Hir, K. M., and Eckardt, K. U. 1993. Colocalization of erythropoietin mRNA and ecto-5′-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin. J. Histochem. Cytochem. 41:335-341.
3. Bondurant, M. C. and Koury, M. J. 1986. Anemia induces accumulation of erythropoietin mRNA in the kidney and liver. Mol. Cell. Biol. 6: 2731-2733.
4. Chikuma, M., Masuda, S., Kobayashi, T., Nagao, M. and Sasaki, R. 2000. Tissue-specific regulation of erythropoietin production in the murine kidney, brain, and uterus. Am. J. Physiol. Endocrinol. Metab. 279: 1242-1248.
5. Dordal, M. S., Wang, F. F. and Goldwasser, E. 1985. The role of carbohydrate in erythropoietin action. Endocrinology 116: 2293-2299.
6. Erslev, A. J., Wilson, J. and Caro, J. 1987. Erythropoietin titers in anemic, nonuremic patients. J. Lab. Clin. Med. 109: 429-433.
7. Eschbach, J. W. 1989. The anemia of chronic renal failure: pathophysiology and the effects of recombinant erythropoietin. Kidney Int. 34: 134-148.
8. Goto, M., Murakami, A., Akai, K., Kawanishi, G., Ueda, M., Chiba, H. and Sasaki, R. 1989. Characterization and use of monoclonal antibodies directed against human erythropoietin that recognize different antigenic determinants. Blood 74: 1415-1423.
9. Goto, Y., Manabe, N., Uchio-Yamada, K., Yamaguchi-Yamada, M., Inoue, N., Yamamoto, Y., Ogura, A., Nagano, N. and Miyamoto, H. 2004. Augmented cytoplasmic Smad4 induces acceleration of TGF-β1 signaling in renal tubulointerstitial cells of hereditary nephrotic ICGN mice with chronic renal fibrosis; possible role for myofibroblastic differentiation. Cell Tissue Res. 315: 209-212.
10. Kersteins, H. M., Poddinghe, P. J. and Hanselaar, A. G. 1995. A novel in situ hybridization signal amplification method based on the deposition of biotinylated tyramide. J. Histochem. Cytochem. 43: 347-352.
11. Komatsu, K., Manabe, N., Kiso, M., Shimabe, M. and Miyamoto, H. 2003. Soluble Fas (FasB) regulates luteal cell apoptosis during luteolysis in murine ovaries. Mol. Reprod. Dev. 65: 345-352.
12. Koury, M. J. and Bondurant, M. C. 1990. Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells. Science 248: 378-381.
13. Koury, S. T., Koury, M. J., Bondurant, M. C., Caro, J. and Graber S. E. 1989. Quantitation of erythropoietin-producing cells in kidneys of mice by in situ hybridization: correlation with hematocrit, renal erythropoietin mRNA, and serum erythropoietin concentration. Blood 74: 645-651.
14. Krantz, S. B. 1991. Erythropoietin. Blood 77: 419-434.
15. Lacombe, C., Da Silva, J. L., Bruneval, P., Fournier, J. G., Wendling, F., Casadevall, N., Camilleri, J. P., Bariety, J., Varet, B. and Tambourin, P. 1988. Peritubular cells are the site of erythropoietin synthesis in the murine hypoxic kidney. J. Clin. Invest. 81: 620-623.
16. Loya, F., Yang, Y., Lin, H., Goldwasser, E. and Albitar, M. 1994. Transgenic mice carrying the erythropoietin gene promoter linked to lacZ express the reporter in proximal convoluted tubule cells after hypoxia. Blood 84: 1831-1836.
17. Maxwell, A. P., Lappin, T. R., Johnston, C. F., Bridges, J. M. and McGeown, M. G. 1990. Erythropoietin production in kidney tubular cells. Br. J. Haematol. 74: 535-539.
18. Maxwell, P. H., Osmond, M. K., Pugh, C. W., Heryet, A., Nicholls, L. G., Tan, C. C., Doe, B. G., Ferguson, D. J., Johnson, M. H. and Ratcliffe, P. J. 1993. Identification of the renal erythropoietin-producing cells using transgenic mice. Kidney Int. 44: 1149-1162.
19. National kidney foundation anemia work group. 1997. NKF-DOQI clinical practice guidelines for the treatment of anemia of chronic renal failure. Am. J. Kidney Dis. 30 (Suppl. 3): S192-S240.
20. Ogura, A., Asano, T., Matsuda, J., Takano, K., Nakagawa, M. and Fukui, M. 1989. Characteristics of mutant mice (ICGN) with spontaneous renal lesion: a new model for human nephrotic syndrome. Lab. Anim. 23: 169-174.
21. Ogura, A., Asano, T., Suzuki, O., Yamamoto, Y., Noguchi, Y., Kawaguchi, H. and Yamaguchi, Y. 1994. Hereditary nephrotic syndrome with progression to renal failure in a mouse model (ICGN strain): clinical study. Nephron 68: 239-244.
22. Ogura, A., Fujimura, H., Asano, T., Koura, M., Naito, I. and Kobayashi, Y. 1995. Early ultrastructural glomerular alterations of neonatal nephrotic mice (ICGN strain). Vet. Pathol. 32: 321-323.
23. 2-supply to the kidneys and the production of erythropoietin. Respir. Physiol. 77: 111-117.
24. Ratcliffe, P.J. 1993. Molecular biology of erythropoietin. Kidney. Int. 44: 887-904.
25. Remuzzi, G. and Minetti, L. 2000. Hematologic consequences of renal failure. pp. 2079-2102. In: The Kidney, vol 2, 6th ed. (Brenner, B. M. ed.), Saunders, Philadelphia.
26. Sasaki, R., Masuda, S. and Nagao, M. 2000. Erythropoietin: multiple physiological functions and regulation of biosynthesis. Biosci. Biotechnol. Biochem. 64: 1775-1793.
27. Sato, Y., Tsuchiya, B. and Kameya, T. 2001. Tyramide in situ hybridization of paraffin-embedded sections, immunohistochemistry and the DNA extraction from paraffin-embedded samples, pp. 98-107. In: Histochemistry and Cytochemistry 2001 (the Japan Society of Histochemistry and Cytochemistry ed.), Gakusaikikaku, Tokyo (in Japanese).
28. Shoemaker, C.B. and Mitsock, L.D. 1986. Murine erythropoietin gene: cloning, expression,and human gene homology. Mol. Cell. Biol. 6: 849-858.
29. Tamura, K,. Manabe, N., Uchio, K., Miyamoto, M., Yamaguchi, M., Ogura, A., Yamamoto, Y., Nagano, N., Furuya, Y. and Miyamoto, H. 1999. Characteristic changes in carbohydrate profile in the kidney of the hereditary nephrotic mice (ICGN strain). J. Vet. Med. Sci. 62: 379-390.
30. Tisher, C. C. and Madsen, K. M. 2000. Hematologic consequences of renal failure. pp. 3-67. In: The Kidney, vol 1, 6th ed. (Brenner, B. M. ed.), Saunders, Philadelphia.
31. Uchio, K., Manabe, N., Kinoshita, A., Tamura, K., Miyamoto, M., Ogura, A., Yamamoto, Y. and Miyamoto, H. 1999. Abnormalities of extracellular matrices and transforming growth factor-beta1 localization in the kidney of the hereditary nephrotic mice (ICGN strain). J. Vet. Med. Sci. 61: 769-776.
32. Uchio, K., Manabe, N., Tamura, K., Miyamoto, M., Yamaguchi, M., Ogura, A., Yamamoto, Y. and Miyamoto, H. 2000. Decreased activities of matrix metalloproteinases in the kidney of the hereditary nephrotic mice (ICGN strain). Nephron 86: 145-151.
33. Uchio-Yamada, K., Manabe, N., Yamaguchi, M., Akashi, N., Goto, Y., Yamamoto, Y. and Ogura, A. 2001. Localization of extracellular matrix receptors in ICGN mice, a strain of mice with hereditary nephrotic syndrome. J. Vet. Med. Sci. 63: 1171-1178.
34. Yamaguchi, M., Manabe, N., Uchio-Yamada, K., Akashi, N., Yamamoto, Y., Ogura, A. and Miyamoto, H. 2001. Localization of proliferative and apoptotic cells in the kidneys of ICR-derived glomerulonephritis (ICGN) mice. J. Vet. Med. Sci. 63: 781-787.
35. Yamaguchi-Yamada, M., Manabe, N., Uchio-Yamada, K., Akashi, N., Goto, Y., Miyamoto, Y., Nagao, M., Yamamoto, Y., Ogura, A. and Miyamoto, H. 2004. Anemia with chronic renal disorder and disrupted metabolism of erythropoietin in ICR-derived glomerulonephritis (ICGN) mice. J. Vet. Med. Sci. 66: 423-431.
36. Yamaguchi-Yamada, M., Manabe, N., Goto, Y., Miyamoto, Y., Miyamoto, K., Nagao, M., Yamamoto, Y., Ogura, A. and Miyamoto, H. 2004. Improvement of anemia associated with chronic renal failure by recombinant human erythropoietin treatment in ICR-derived glomerulonephritis (ICGN) mice. J. Vet. Med. Sci. 66: 883-886.
37. Zaroulis, C. G., Hoffman, B. J. and Kourides, L. A. 1981. Serum concentrations of erythropoietin measeured by radioimmunoassay in hematologic disorders and chronic renal failure. Am. J. Hematol. 11: 85-92.