Inhibition of lipid droplet accumulation in macrophages by triterpenoids produced from Torametes orientaris

Biological and Pharmaceutical Bulletin

Volumn 28, Issue 10, 2005, Pages 1925-1927

  Ohshiro, Taichi ^a   Namatame, Ichiji ^a   Ochiai, Kana ^b   Kawagishi, Hirokazu ^b   Tomoda, Hiroshi ^a  

^a KITASATO UNIVERSITY   (Japan)

^b SHIZUOKA UNIVERSITY   (Japan)

Author keywords

Atherosclerosis; Lipid droplet accumulation; Macrophage; Neutral lipid synthesis; Torametes orientaris; Triterpenoid inhibitor

Indexed keywords

CHOLESTEROL ESTER; FAT DROPLET; TRIACYLGLYCEROL; TRITERPENOID;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CHEMICAL ANALYSIS; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DRUG ISOLATION; DRUG SCREENING; LIPID STORAGE; LIPOGENESIS; MACROPHAGE; MEDICINAL PLANT; MOUSE; NONHUMAN; TORAMETES ORIENTARIS;

ANIMALS; CHOLESTEROL ESTERS; CHROMATOGRAPHY, THIN LAYER; FUNGI; LIPID METABOLISM; MACROPHAGES; MICE; TRIGLYCERIDES; TRITERPENES;

EID: 26444525348     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.28.1925     Document Type: Article

References (19)

1. Goldstein J. L., Ho Y. K., Basu S. K., Brown M. S., Proc. Natl. Acad. Sci. U.S.A., 76, 333-337 (1979).
2. Brown M. S., Goldstein J. L., Krieger M., Ho Y. K., Anderson R. G., J. Cell Biol., 82, 597-613 (1979).
3. Scaffner T., Taylor K., Bartucci E. J., Fischer-Dzoga K. F., Beeson J. H., Glagov S., Wisser, R. W., Am. J. Pathol., 100, 57-73 (1980).
4. Gerrtiy R. G., Am. J. Pathol., 103, 181-190 (1981).
5. Namatame I., Tomoda H., Si S., Yamaguchi Y., Masuma R., Ōmura S., J. Antibiot., 52, 1-6 (1999).
6. Namatame I., Tomoda H., Tabata N., Si S., Ōmura S., J. Antibiot., 52, 7-12 (1999).
7. Matsuda D., Namatame I., Tomoda H., Kobayashi S., Zocher R., Kleinkauf H., Ōmura S., J. Antibiot., 57, 1-9 (2004).
8. Namatame I., Tomoda H., Ishibashi S., Ōmura S., Proc. Natl. Acad. Sci. U.S.A., 101, 737-742 (2004).
9. Tomoda H., Namatame I., Si S., Kawaguchi K., Masuma R., Namikoshi M., Ōmura S., J. Antibiot., 52, 851-856 (1999).
10. Tomoda H., Namatame I., Tabata N., Kawaguchi K., Si S., Ōmura S., J. Antibiot., 52, 857-861 (1999).
11. Namatame I., Tomoda H., Matsuda D., Tabata N., Kobayashi S., Ōmura S., Proc. Jpn. Acad., 78, 45-50 (2002).
12. Bae K.-G., Min T.-J., J. Korean Chem. Soc., 44, 37-44 (2000).
13. Chairul, Tokuyama T., Nishizawa M., Shiro M., Tokuda H., Hayashi Y., Phytochemistry, 29, 923-928 (1990).
14. Kawagishi H., Li H., Tanno O., Inoue S., Ikeda S., Ohnishi-Kameyama M., Nagata T., Phytochemistry, 46, 959-961 (1997).
15. Namatame I., Tomoda H., Arai H., Inoue K., Ōmura S., J. Biochem., 125, 319-327 (1999).
16. Bligh E. G., Dyer W., Can. J. Biochem. Physiol., 37, 911-917 (1959).
17. Liscum L., Ruggiero R. M., Faust J. R., J. Cell Biol., 108, 1625-1636 (1989).
18. Aikawa K., Furuchi T., Fujimoto Y., Arai H., Inoue K., Biochim. Biophys. Acta, 1213, 127-134 (1994).
19. Fujioka T., Yao K., Hamano K., Hosoya T., Kagasaki T., Furukawa Y., Haruyama H., Sato S., Koga T., Tsujita Y., J. Antibiot., 49, 409-413 (1996).