Multi-organic risk assessment of estrogenic properties of octyl-methoxycinnamate in vivo: A 5-day sub-acute pharmacodynamic study with ovariectomized rats

Toxicology

Volumn 215, Issue 1-2, 2005, Pages 90-96

  Klammer, Holger ^a   Schlecht, Christiane ^a   Wuttke, Wolfgang ^a   Jarry, Hubertus ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Benchmark dose approach; BMD; Estrogen receptors; Multi organic risk assessment; Octyl methoxycinnamate; Rat

Indexed keywords

4 METHOXYCINNAMIC ACID 2 ETHYLHEXYL ESTER; BIOLOGICAL MARKER; ESTRADIOL VALERATE; EUSOLEX 2292; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROTEIN DERIVATIVE; TRIACYLGLYCEROL; TRUNCATED ESTROGEN RECEPTOR PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ESTROGEN ACTIVITY; FEMALE; GENE EXPRESSION; HYPOPHYSIS; METABOLIC PARAMETERS; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK ASSESSMENT; SKIN PROTECTION;

ANIMALS; BODY WEIGHT; CINNAMATES; COMPLEMENT C3; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROGEN RECEPTOR BETA; ESTROGENS, NON-STEROIDAL; FEMALE; LIPIDS; LIVER; ORGAN SIZE; PITUITARY GLAND; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, IGF TYPE 1; RECEPTORS, ESTROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK ASSESSMENT; SUNSCREENING AGENTS; UTERUS;

ANIMALIA;

EID: 26444495117     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2005.06.026     Document Type: Article

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