Dose-intensive thoracic radiation therapy for patients at high risk with early-stage non-small-cell lung cancer

Clinical Lung Cancer

Volumn 6, Issue 6, 2005, Pages 350-354

  Bogart, Jeffrey A ^a   Alpert, Tracy E ^a   Kilpatrick, Mary C ^a   Keshler, Bonnie L ^a   Pohar, Surjeet S ^a   Shah, Hemangini ^a   Dexter, Elisabeth ^a   Aronowitz, Jesse N ^b  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

3 dimensional therapy; Conformal radiation therapy; Hypofractionation

Indexed keywords

ANTINEOPLASTIC AGENT;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; CANCER GROWTH; CANCER STAGING; CANCER SURVIVAL; CLINICAL ARTICLE; COMORBIDITY; DEATH; DYSPNEA; FEASIBILITY STUDY; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HUMAN; LARGE CELL CARCINOMA; LUNG DISEASE; LUNG FIBROSIS; LUNG NON SMALL CELL CANCER; LUNG TOXICITY; MALE; PNEUMONIA; RADIATION DOSE; RETROSPECTIVE STUDY; SQUAMOUS CELL CARCINOMA;

EID: 26444471422     PISSN: 15257304     EISSN: None     Source Type: Journal    
DOI: 10.3816/CLC.2005.n.014     Document Type: Article

References (29)

1. Jemal A, Murray T, Ward A, et al. Cancer statistics, 2005. CA Cancer J Clin 2005: 55:10-30.
2. Mettlin CJ, Menck HR, Murphy GP, et al. A comparison of breast, colorectal, lung, and prostate cancers reported to the National Cancer Data Base and the Surveillance, Epidemiology and End Results Program. Cancer 1997; 79:2052-2061.
3. Williams DE, Pairoleto PC, Davis CS, et al. Survival of patients surgically treated for stage I lung cancer. J Thorac Cardiovasc Surg 1981; 82:70-76.
4. Havlik RJ, Yancik R, Long S, et al. The National Institute on Aging and the National Cancer Institute SEER collaborative study on comorbidity and early diagnosis of cancer in the elderly. Cancer 1994; 74(suppl 1):2102-2106.
5. Hutchins LF, Unger JM, Crowley JJ, et al. Underrepresentation of patients 65 years of age or older in cancet-treatment trials. N Engl J Med 1999; 341:2061-2067.
6. Henschke CI, McCauley DI, Yankelevitz DF, et al. Early Lung Cancer Action Project: overall design and findings from baseline screening. Lancer 1999; 354:99-105.
7. Rowell NP, Williams CJ. Radical radiotherapy for stage I/II non-small cell lung cancer in patients not sufficiently fit for or declining surgery (medically inoperable): a systematic review. Thorax 2001; 56:628-638.
8. Lagerwaard FJ, Senana S, van Meerbeeck JP, et al. Has 3-D conformal radiotherapy (3D CRT) improved the local tumour control for stage I non-small cell lnng cancer? Radiother Oncol 2002; 63:151-157.
9. Hayman JA, Martel MK, Ten Haken RK, et al. Dose escalation in non-small-cell lung cancer using three-dimensional conformal radiation therapy: update of a phase I trial. J Clin Oncol 2001; 19:127-136.
10. Bradley JD, Graham MV, Winter KW, et al. Acute and late toxicity results of RTOG 9311: a dose escalation study using 3D conformal radiation therapy in patients with inoperable non-small cell lung cancer. Int J Radiat Oncol Biol Phys 2003; 57(suppl 1): S137-S138.
11. Cox JD, Pajak TF, Marcial VA, et al. Interruptions adversely affect local control and survival with hyperfractionated radiation therapy of carcinomas of the upper respiratory and digestive tracts. New evidence for accelerated proliferation from Radiation Therapy Oncology Group Protocol 83 13. Cancer 1992; 69:2744-2748.
12. Withers HR, Taylor JM, Maciejewski B. The hazard of accelerated tumor clonogen repopulation during radiotherapy. Acta Oncol 1988; 27:131-146.
13. Graham MV, Purdy JA, Emami B, et al. Clinical dose-volume histogram analysis for pneumonitis after 3D treatment for non-small cell lung cancer (NSCLC). Int J Radiat Oncol Biol Phys 1999; 45:323-329.
14. National Cancer Institute Common Toxicity Criteria. Cancer Therapy Evaluation Program Web site. Available at: http://ctep.cancer.gov/forms/CTCv20_4-30-992.pdf). Accessed March 29, 2005.
15. Kyasa MJ, Jazieh AR. Characteristics and outcomes of patients with unresected early-stage non-small cell lung cancer. South Med J 2002; 95:1149-1152.
16. Fowler JF, Chappell R. Non-small cell lung tumors repopulate rapidly during radiation therapy. Int J Radiat Oncol Biol Phys 2000; 46:516-517.
17. Fowler JF. How worthwhile are short schedules in radiotherapy? A series of exploratory calculations. Radiother Oncol 1990; 18:165-181.
18. Sibley GS. Radiotherapy for patients with medically inoperable Stage I nonsmall cell lung carcinoma: smaller volumes and higher doses - a review. Cancer 1988; 82:433-438.
19. Bradley JD, Ieumwananonthachai N, Purdy JA, et al. Gross tumor volume, critical prognostic factor in patients treated with three-dimensional conformal radiation therapy for non-small-cell lung carcinoma. Int J Radiat Oncol Biol Phys 2002; 52:49-57.
20. Rosenzweig KE, Dladla N, Schindelheim R, et al. Three-dimensional conformal radiation therapy (3D-CRT) for early-stage non-small-cell lung cancer. Clin Lung Cancer 2001; 3:141-144.
21. Henning GT, Littles JF, Martel ML, et al. Preliminary results of 92.4 Gy or more for non-small cell lung cancer. Int J Radiat Oncol Biol Phys 2002; 48(suppl 1):233.
22. Maguire PD, Marks LB, Sibley GS, et al. 73.6 Gy and beyond; hyperfractionated, accelerated radiotherapy for non-small-cell lung cancer. J Clin Oncol 2001; 19:705-711.
23. Roach M III, Gandara DR, Yuo HS, et al. Radiation pneumonitis following combined modality therapy for lung cancer: analysis of prognostic factors. J Clin Oncol 1995; 13:2606-2612.
24. Slotman BJ, Antonisse IE, Njo KH. Limited field irradiation in early stage (T1-2N0) non-small cell lung cancer. Radiother Oncol 1996; 41:41-44.
25. Cheung PC, Yeung LT, Basrur V, et al. Accelerated hypofractionation for early-stage non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 2002; 54:1014-1023.
26. Phase I study of accelerated 3-dimensional conformal radiotherapy in patients with stage I non-small cell lung cancer with pulmonary dysfunction. CALGB-39904. Available at: http://cancer.gov/search/viewclinicaltrials.aspx?cdrid= 68409&version=healthprofessional&protocolserchid=1057893. Accessed March 29, 2005.
27. Onishi H, Nagara Y, Shiraro H, et al. Stereotactic hypofractionated high-dose irradiation for stage I non-small cell lung carcinoma: clinical outcomes in 273 cases of a Japanese multi-institutional study. Proc Am Soc Clin Oncol 2004; 23:617 (Abstract #7003).
28. Timmerman R, Papier L, McGrry R, et al. Extracranial stereotactic radioablation: results of a phase I study in medically inoperable stage I non-small cell lung cancer. Chest 2003; 124:1946-1955.
29. A phase II trial of stereotactic body radiation therapy (SBRT) in the treatment of patients with medically inoperable stage I/II non-small cell lung cancer. RTOG 0236. Available at: http://rtog.org/summaries/lung.html. Accessed March 29, 2005.