Methacholine bronchial provocation measured by spirometry versus wheeze detection in preschool children

BMC Pediatrics

Volumn 5, Issue , 2005, Pages

  Bentur, Lea ^a,c   Beck, Raphael ^a,c   Elias, Nael ^a,c   Barak, Asher ^b   Efrati, Ori ^b   Yahav, Yaacov ^b   Vilozni, Daphna ^b  

^a MEYER CHILDREN S HOSPITAL   (Israel)

^b SHEBA MEDICAL CENTER   (Israel)

^c TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BRONCHODILATING AGENT; METHACHOLINE; STEROID; BRONCHOCONSTRICTING AGENT; DIAGNOSTIC AGENT; METHACHOLINE CHLORIDE;

ARTICLE; ASTHMA; BREATHING RATE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG RESPONSE; DRUG SAFETY; FEASIBILITY STUDY; FEMALE; FORCED EXPIRATORY VOLUME; HEART RATE; HUMAN; HYPERPNEA; INHALATION TEST; INTERMETHOD COMPARISON; LUNG AUSCULTATION; MALE; OXYGEN SATURATION; PRESCHOOL CHILD; SPIROMETRY; STUDENT T TEST; TIDAL VOLUME; WHEEZING; ABNORMAL RESPIRATORY SOUND; AUSCULTATION; CHILD; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; METHODOLOGY; PATHOPHYSIOLOGY;

ASTHMA; AUSCULTATION; BRONCHIAL PROVOCATION TESTS; BRONCHOCONSTRICTOR AGENTS; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEASIBILITY STUDIES; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; MALE; METHACHOLINE CHLORIDE; RESPIRATORY SOUNDS; SPIROMETRY;

EID: 26444460875     PISSN: 14712431     EISSN: 14712431     Source Type: Journal    
DOI: 10.1186/1471-2431-5-19     Document Type: Article

References (29)

1. Cockcroft DW: Bronchoprovocation methods: direct challenges. Clin Rev Allergy Immunol 2003, 24:19-26.
2. Spiropoulos K, Stevens J, Eigen H, Spiropoulos A: Specificity and sensitivity of methacholine challenge test in children with normal and hyper-reactive airways. Acta Paediatr Scand 1986, 75:737-743.
3. Guidelines for Methacholine and exercise challenge testing - 1999. The Official Statement of the American Thoracic Society. Am J Respir Crit Care Med 2000, 161:309-329.
4. Noviski N, Cohen L, Springer C, Bar-Yishay E, Avital A, Godfrey S: Bronchial provocation determined by breath sounds compared with lung function. Arch Dis Child 1991, 66:952-955.
5. Wilson NM, Bridge P, Silverman M: The measurement of methacholine responsiveness in 5-year-old children: three methods compared. Eur Respir J 1995, 8:364-370.
6. Wilts M, Hop WC, van der Heyden GH, Kerrebijn KF, de Jongste JC: Measurement of bronchial responsiveness in young children: comparison of transcutaneous oxygen tension and functional residual capacity during induced bronchoconstriction and dilatation. Pediatr Pulmonol 1992, 12:181-185.
7. Springer C, Godfrey S, Picard E, Uwyyed K, Rotschild M, Hanania S, Noviski N, Avital A: Efficacy and Safety of Methacholine Bronchial Challenge performed by auscultation in young asthmatic children. Am J Respir Crit Care Med 2000, 162:857-860.
8. Vilozni D, Barker M, Jellouschek H, Heimann G, Blau H: An interactive computer-animated system (SpiroGame) facilitates spirometry in pre-school children. Am J Respir Crit Care Med 2001, 164:2200-2205.
9. Eigen H, Bieler H, Grant D, Christoph K, Terrill D, Heilman DK, Ambrosius WT, Tepper RS: Spirometric pulmonary function in healthy preschool children. Am J Respir Crit Care Med 2001, 163:619-623.
10. Zapletal A, Chalupova J: Forced expiratory parameters in healthy preschool children (3-6 years of age). Pediatr Pulmono 2003, 35:200-207.
11. Aurora P, Stocks J, Oliver C, Saunders C, Castle R, Chaziparasidis G, Bush A: Quality control for spirometry in preschool children with and without lung disease. Am J Respir Crit Care Med 2004, 169:1152-1159.
12. Sprikkelman AB, Grol MH, Lourens MS, Gerritsen J, Heymans HS, van Aalderen WM: Use of tracheal auscultation for the assessment of bronchial responsiveness in asthmatic children. Thorax 1996, 51:317-319.
13. Hayden MJ, Devadason SG, Sly PD, Wildhaber JH, LeSouef PN: Methacholine responsiveness using the raised volume forced expiration technique in infants. Am J Respir Crit Care Med 1997, 155:1670-1675.
14. Martinez FC, Yarza GPE, Ruiz AA, Knorr EJI, Blecua CM, Aramburu MJ: Agreement between tracheal auscultation and pulmonary function in methacholine bronchial inhalation challenge in asthmatic children. An Esp Pediatr 2002, 56:304-309.
15. Global Strategy for Asthma Management and Prevention. National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda; 1995.
16. Zapletal A, Samanek M, Prague TP: Lung function in children and adolescents: Methods, reference values. Basel, Karger 1987.
17. Standardization of spirometry-1994 update. Statement of the American Thoracic Society. Am J Respir Crit Care Med 1995, 153:1107-1236.
18. Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC: Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J 1993:5-40.
19. Crenesse D, Berlioz M, Bourrier T, Albertini M: Spirometry in children aged 3 to 5 years: reliability of forced expiratory maneuvers. Pediatr Pulmonol 2001, 32:56-61.
20. Bland JM, Altman DG: Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986, 1:307-310.
21. Nystad W, Samuelsen SO, Nafstad P, Edvardsen E, Stensrud T, Jaakkola JJ: Feasibility of measuring lung function in preschool children. Thorax 2002, 57:1021-1027.
22. Gracchi V, Boel M, Van der Laag J, Van der Ent CK: Spirometry in young children: should computer-animation programs be used during testing? Eur Respir J 2003, 2:872-875.
23. Kozlowska W, Aurora P, Stocks J: The use of computer-animation programs during spirometry in preschool children. Eur Respir J 2004, 2:494-495.
24. Adinoff AD, Schlosberg RT, Strunk RC: Methacholine inhalation challenge in young children: results of testing and follow-up. Ann Allergy 1988, 61:282-286.
25. Tepper RS: Airway reactivity in infants: a positive response to methacholine and metaproterenol. J Appl Physiol 1987, 62:1155-1159.
26. England SJ, Ho V, Zamel N: Laryngeal constriction in normal humans during experimentally induced bronchoconstriction. J Appl Physiol 1985, 58:352-356.
27. Marchal F, Loos N, Monin P, Peslin R: Methacholine-induced volume dependence of respiratory resistance in preschool children. Eur Respir J 1999, 14(5):1167-74.
28. Sprikkelman AB, Schouten JP, Lourens MS, Heymans HS, van Aalderen WM: Agreement between spirometry and tracheal auscultation in assessing bronchial responsiveness in asthmatic children. Respir Med 1999, 93:102-107.
29. Spence DP, Graham DR, Jamieson G, Cheetham BM, Calverley PM, Earis JE: The relationship between wheezing and lung mechanics during methacholine induced broncho-constriction in asthmatic subjects. Am J Respir Crit Care Med 1996, 154:290-294.