Antihistaminic and antianaphylactic activity of HK-07, a herbal formulation

Indian Journal of Pharmacology

Volumn 37, Issue 5, 2005, Pages 300-303

  Gopumadhavan, S ^a   Rafiq, Mohamed ^a   Venkataranganna, M V ^a   Mitra, S K ^a  

^a Himalaya Health Care   (India)

Author keywords

Hypersensitivity; IgE; Mast cell degranulation

Indexed keywords

ANTIGEN; ANTIHISTAMINIC AGENT; HERBACEOUS AGENT; HISTAMINE; HK 07; IMMUNOGLOBULIN E; UNCLASSIFIED DRUG;

AEROSOL; ANAPHYLACTIC SHOCK; ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHOSPASM; CELL COUNT; CELL DISRUPTION; COMPARATIVE STUDY; CONTROLLED STUDY; CONVULSION; DESENSITIZATION; DISEASE MODEL; DISEASE SEVERITY; DRUG ACTIVITY; DRUG EFFECT; DRUG FORMULATION; DRUG SCREENING; DYSPNEA; EX VIVO STUDY; EXPERIMENTAL MODEL; EXPOSURE; FEMALE; GUINEA PIG; IMMUNOGLOBULIN BLOOD LEVEL; INTESTINE; LATENT PERIOD; MALE; MAST CELL; MESENTERY; MORTALITY; NONHUMAN; PROVOCATION TEST; RAT; SYMPTOM;

EID: 26444454442     PISSN: 02537613     EISSN: None     Source Type: Journal    
DOI: 10.4103/0253-7613.16853     Document Type: Article

References (25)

1. Ring J, Kramer U, Shafer T, Beherendt H. Why are allergies increasing? Curr Opinions Immunol 2001;13:701-8.
2. Spector SL. Overview of comorbid associations of allergic rhinitis. J Allergy Clin Immunol 1997;99:773-80.
3. Passali D, Lauriello M, Mezzedimi C, Bellussi L. Nasal allergy and atmospheric pollution. Int J Pediatr Otorhinolaryngol 1999;49:257-60.
4. Hansen I, Klimek L, Mosges R, Hormann K. Mediators of inflammation in the early and the late phase of allergic rhinitis. Curr Opin Allergy Clin Immunol 2004;4:159-63.
5. Salib RJ, Drake-Lee A, Howarth PH. Allergic rhinitis: past, present and the future. Clin Otolaryngol 2003; 28: 291-303.
6. Wu CN. Safety and anti-inflammatory activity of curcumin: A component of turmeric (Curcuma longa). J Altern Complement Med 2003;9:161-8.
7. Bharti AC, Donato N, Singh S, Aggarwal BB. Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor- κB and IκBα kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. Blood 2003;101:1053-62.
8. Gagliardo R, Chanez P, Mathieu M, Bruno A, Costanzo G, Gougat C, et al. Persistent activation of nuclear factor- κB signaling pathway in severe uncontrolled asthma. Am J Respir Crit Care Med 2003;168:1190-8.
9. Palit G, Singh SP, Singh N, Kohli RP, Bhargava KP. An experimental evaluation of anti-asthmatic plant drugs from ancient Ayurvedic medicine. Aspects Aller Appl Immunol 1983;16:36-41.
10. Godhwani S, Godhwani GL, Vyas DS. Ocimum sanctum: An experimental study evaluating its anti-inflammatory, analgesic and antipyretic activity in animals. J Ethnopharmacol 1987;21:152-63.
11. Kelm MA, Nair MG, Strasburg GM, Dewitt DL. Antioxidant and cyclooxygenase inhibitory phenolic compounds from Ocimum sanctum Linn. Phytomed 2000;7:7-13.
12. Chakraborty A, Brantner AH. Study of alkaloids from Adhatoda vasica Nees. on their anti-inflammatory activity. Phytother Res 2001;15:532-44.
13. Dhuley JN. Antitussive effect of Adhatoda vasica extract on mechanical or chemical stimulation-induced coughing in animals. J Ethnopharmacol 1999;67:361-5.
14. Dahanukar SA, Karandikar SM. Evaluation of anti-allergic activity of Piper longum. Indian Drugs 1984;21:377-83.
15. Nosal'ova G, Mokry J, Hassan KM. Antitussive activity of the fruit extract of Emblica officinalis Garetn. (Euphorbiaceae). Phytomed 2003;10:583-9.
16. Bhattacharya A, Ghosal S, Bhattacharya SK. Antioxidant activity of tannoid principles of Emblica officinalis (amla) in chronic stress induced changes in rat brain. Indian J Exp Biol 2000;38:877-80.
17. Sabu MC, Kuttan R. Antidiabetic activity of medicinal plants and its relation ship with their antioxidant property. J Ethnopharmacol 2002;81:155-60.
18. Kiuchi F, Iwakami S, Shibuya M, Hanaoka F, Sankawa U. Inhibition of prostaglandin and leukotriene biosynthesis by gingerols and diarylheptanoids. Chem Pharm Bull 1992;40:387-91.
19. Seo WG, Pae HO, Oh GS, Chai KY, Kwon TO, Yun YG, et al. Inhibitory effects of methanol extract of Cyperus rotundus rhizomes on nitric oxide and superoxide productions by murine macrophage cell line RAW 264.7 cells. J Ethnopharmacol 2001;76:59-64.
20. Mitra SK, Gopumadhavan S, Venkataranganna MV, Anturlikar SD. Antiasthmatic and antianaphylactic effect of E-721B, a herbal formulation. Indian J Pharmacol 1999;31:133-7.
21. Sengupta K, Kolhapure SA. Evaluation of efficacy and safety of HK-07 tablets in upper and lower respiratory tract allergic diseases in children. Med Update 2004;12:37-46.
22. Armitage AK, Boswood J, Large BJ. Thioxanthines with potent bronchodilator and coronary dilator properties. Br Pharm Chemother 1961;16:59-76.
23. Marone G, Casolara V, Patella V. Florio G, Triggiani M. Molecular and cellular biology of mast cells and basophils. Int Arch Allergy Immunol 1997;114:207-17.
24. Schroeder JT, MacGlashan DW Jr, Subotka K, White JM, Lichtenstein LM. IgE-dependent IL-4 secretion by human basophils. The relation ship between cytokine production and histamine release in mixed leukocyte cultures. J Immunol 1994;153:1808-17.
25. Burrows B, Martinez FD, Halonan M, Barbee RA, Cline MG. Association of asthma with serum IgE levels and skin test reactivity to allergens. N Engl J Med 1989;32:271-7.