Caution in the interpretation of MLS

Genetic Epidemiology

Volumn 14, Issue 6, 1997, Pages 1079-1083

  Eichenbaum Voline, Sophie ^a   Génin, Emmanuelle ^b   Babron, Marie Claude ^b   Margaritte Jeannin, Patricia ^b   Prum, Bernard ^a   Clerget Darpoux, Françoise ^b  

^a CNRS   (France)

^b INSERM   (France)

Author keywords

Information content; Linkage; MLS; Type I error

Indexed keywords

CONFERENCE PAPER; ERROR; GENE FREQUENCY; GENETIC DISTANCE; GENETIC LINKAGE; GENOTYPE; MAXIMUM LIKELIHOOD METHOD; SIMULATION; STATISTICS;

ALLELES; DATA INTERPRETATION, STATISTICAL; GENE FREQUENCY; GENETIC MARKERS; HUMANS; LIKELIHOOD FUNCTIONS; LINKAGE (GENETICS); PREDICTIVE VALUE OF TESTS;

EID: 2642712520     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2272(1997)14:6<1079::AID-GEPI86>3.0.CO;2-E     Document Type: Conference Paper

References (4)

1. Kruglyak L, Lander ES (1995a): Complete multipoint sib pair analysis of qualitative and quantitative traits. Am J Hum Genet 57:439-454.
2. Kruglyak L, Lander ES (1995b): Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11:241-247.
3. Risch N (1990): Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs. Am J Hum Genet 46:242-253.
4. Shah S, Green JR (1994): Disease susceptibility genes and the sib-pair method: a review of recent methodology. Ann Hum Genet 58:381-395.