Suppression of mutagenic activity of a series of 5HT(2c) receptor agonists by the incorporation of a gem-dimethyl group: SAR using the Ames test and a DNA unwinding assay

Mutagenesis

Volumn 13, Issue 4, 1998, Pages 397-403

  Albertini, Silvio ^a   Bös, Michael ^a   Gocke, Elmar ^a   Kirchner, Stephan ^a   Muster, Wolfgang ^a   Wichmann, Jürgen ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENE; PYRAZOLE DERIVATIVE; PYRROLE DERIVATIVE; SEROTONIN 2C AGONIST;

AMES TEST; ANIMAL TISSUE; ARTICLE; DNA DENATURATION; MUTAGENIC ACTIVITY; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; DNA; HUMANS; MUTAGENICITY TESTS; PYRROLES; RATS; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, SEROTONIN; SALMONELLA TYPHIMURIUM; SEROTONIN AGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 2642712460     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/13.4.397     Document Type: Article

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