Enhanced sensitivity to tumor necrosis factor-α in doxorubicin- resistant tumor cell lines due to down-regulated c-erbB2

International Journal of Cancer

Volumn 77, Issue 1, 1998, Pages 101-106

  Sleufer, Stefan ^a   Asschert, Johanna G W ^a   Timmer Bosscha, Hetty ^a   Mulder, Nanno H ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; DOXORUBICIN; TUMOR NECROSIS FACTOR ALPHA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CYTOTOXICITY; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG SMALL CELL CANCER; PRIORITY JOURNAL; RECEPTOR BINDING; SPECTROPHOTOMETRY; TUMOR CELL CULTURE;

ANTIBIOTICS, ANTINEOPLASTIC; CARCINOMA, SMALL CELL; DOWN-REGULATION; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, ERBB-2; HUMANS; LUNG NEOPLASMS; RECEPTOR, ERBB-2; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 2642708408     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19980703)77:1<101::AID-IJC16>3.0.CO;2-H     Document Type: Article

References (23)

1. BROCKHAUS, M., SCHOENFELD, H.J., SCHLAEGER, E.J., HUNZIKER, W., LESSLAUER, W. and LOETSCHER, H., Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies. Proc. nat. Acad. Sci. (Wash.), 87, 3127-3131 (1990).
2. COUSSBNS, L., YANG-FENG, T.L., LIAO, Y.C., CHEN, E., GRAY, A., MCGRATH, J., SEEBURG, P.M., LIBERMANN, T.W., SCHLESSINGER, J., FRANCKE, U., LEVINSON, A. and ULLRICH, A., Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science, 230, 1132-1139 (1985).
3. FRUEHAUF, J.P., MIMNAUGH, E.G. and SINHA, B.K., Doxorubicin-induced cross-resistance to tumor necrosis factor (TNF) related to differential processing. J. Immunother., 10, 165-173 (1991).
4. FUKUSHIGE, S.I., MATSUBARA, K.I., YOSHIDA, M., SUSAKI, M., SUZUKI, T., SEMBA, K., TOYOSHIMA, K. and YAMAMOTO, T., Localisation of a novel v-erbB related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line. Mol. cell. Biol., 6, 955-958 (1986).
5. HUDZIAK, R.M., LEWIS, G.D., SHALABY, M.R., EESSALU, T.E., AGGARWAL, B.B., ULLRICH, A. and SKEPARD, H.M., Amplified expression of the HER2/ERBB2 oncogene induces resistance to tumor necrosis factor α in NIH 3T3 cells. Proc. nat. Acad. Sci. (Wash.), 85, 5102-5106 (1988).
6. HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor. Mol cell. Biol., 9, 1165-1172 (1989).
7. 2 in breast carcinoma cells. Oncogene, 10, 2297-2305 (1995).
8. KEITH, W.N., DOUGLAS, F., WISHART, G.G., MCCALLUM, H.M., GEORGE, W.D., KAYE, S.B. and BROWN, R., Co-amplification of erbB2, topoisomerase IIα and retinoic acid receptor a genes in breast cancer and allelic loss at topoisomerase I on chromosome 20. Europ. J. Cancer, 29A, 1469-1475 (1993).
9. L and tamoxifen-induced apoptosis in human MCF-7 breast cancer cells. Clin. Cancer Res., 2, 1215-1219 (1996).
10. LICHTENSTEIN, A., GERA, J.F., ANDREWS, J., BERENSON, J. and WARE. C.F., Inhibitors of ADP-ribose polymerase decrease the resistance of HER2/neu-expressiim cancer cells to the cytotoxic effects of tumor necrosis factor. J. Immunol., 146, 2052-2058 (1990).
11. LlENARD, D., EWALENKO, P., DELMOTTE, J.J., RENARD, N. and LEJEUNE. F.J., High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma. J. clin. Oncol., 10, 52-60 (1992).
12. Liu, Z.G., HSU, H., GOEDDEL, D.V. and KARIN, M., Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-KB activation prevents cell death. Cell, 87, 565-576 (1996).
13. MEIJER, C., MULDER, N.H., TIMMER-BOSSCHA, H., PETERS, W.H.M. and DE VRIES, E.G.E., Combined in-vitro modulation of adriamycin resistance. Int. J. Cancer, 49, 582-586 (1991).
14. MORABITO, F., FILANGERI, M., CALLEA, I., SCULLI, G., CALLEA, V., FRACCHIOLLA, N.S., NERI, A. and BRUGIATELLI, M., Bcl-2 protein expression and p53 gene mutation in chronic lymphocytic leukemia: correlation with in vitro sensitivity to chlorambucil and purine analogs. Haematologica, 82, 16-20 (1997).
15. SAFRIT, J.F., BELLDEGRUN, A. and BONAVIDA, B., Sensitivity of human renal eell carcinoma lines to TNF, adriamycin, and combination: role of TNF mRNA induction in overcoming resistance. J. Urol. 149, 1202-1208 (1992).
16. SALMON, S.E., SOEHNLEN, B., DALTON, W.S., MELTZER, P. and SCUDERI, P., Effects of tumor necrosis factor on sensitivity and multidrug resistant human leukemia and myeloma cell lines. Blood, 74, 1723-1727 (1989).
17. SLEIJFER, S. and MULDER, N.H., Tumour necrosis factor: The decline and fall of a biological agent and its resurrection. Clin. Oncol., 6, 127-132 (1994).
18. SLOVAK, M.L., Ho, J.P., COLE, S.P.C., DEELEY, R.G., GREENBERGER, L., DE VRIES, E.G.E., BROXTERMAN, H., SCHEFFER, G.L. and SCHEPER, R.J., The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: evidence that chromosome breakage plays a key role in MRP or LRP gene amplification. Cancer Res., 55, 4214-4219 (1995).
19. TARTAGLIA, L.A., ROTHE, M., HU, Y.F. and GOEDDEL, D.V., Tumor necrosis factor's cytotoxic activity is signalled by the p55 TNF receptor. Cell, 73, 213-216 (1993).
20. 4 sublines with increasing adriamycin resistance. Int. J. Cancer, 61, 375-380 (1995).
21. WITHOFF, S., KEITH, W.N., KNOL, A.J., COUTTS, J.C., HOARE, S.F., MULDER, N.H. and DE VRIES, E.G.E., Selection of a subpopulation with less DNA topoisomerase Hot gene copies in a doxorubicin-resistant cell line panel. Brit. J. Cancer, 74, 502-507 (1996).
22. ZULSTRA, J.G., DE VRIES, E.G.E. and MULDER, N.H., Multifactorial drug resistance in an adriamycin-resistant human small cell lung carcinoma cell line. Cancer Res., 47, 1780-1784 (1987).
23. ZYAD, A., BENARD, J., TURSZ, T., CLARKE, R. and CHOUAIB, S., Resistance to TNF-α and adriamycin in the human breast cancer MCF-7 cell line: relationship to MDR1, MnSOD, and TNF gene expression. Cancer Res., 54, 825-831 (1994).