Effect of intrathecal or intracerebroventricular administration of OFQ on pain threshold and acpuncture analgesia in rats

Acta Physiologica Sinica

Volumn 49, Issue 5, 1997, Pages 575-580

  Zhang, Xiu Lin ^a   Zhu, Chong Bin ^a   Xu, Shao Fen ^a   Cao, Xiao Ding ^a   Wu, Gen Cheng ^a   Li, Mo Yi ^b   Cui, Da Fu ^b   Chi, Cheng Wu ^b  

^a FUDAN UNIVERSITY   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Acupuncture analgesia; Anti sense oligonucleotide; Central nervous system; Orphanin FQ; Pain modulation

Indexed keywords

NEUROPEPTIDE; NOCICEPTIN;

ACUPUNCTURE ANALGESIA; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HYPERALGESIA; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; NEUROMODULATION; NONHUMAN; PAIN THRESHOLD; RAT; TAIL FLICK TEST;

ACUPUNCTURE ANALGESIA; ANIMALS; ELECTROACUPUNCTURE; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SPINAL; MALE; OPIOID PEPTIDES; PAIN THRESHOLD; RATS; RATS, SPRAGUE-DAWLEY;

EID: 2642662493     PISSN: 03710874     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Reinscheid RK, Nothacker HP, Bourson A, et al. Orphanin FQ: A neuropeptide that activates an opioid like G-protein-coupled receptor. Science, 1995, 270; 792-794
2. Meunier JC, Mollereau C, Toll L, et al. Isolation and structure of the endogenous agonist of opioid receptor -like ORL1 receptor. Nature, 1995, 377: 532-535
3. Mollereau C, Parmentier M, Mailleux P, et al. ORL1, a novel member of the opioid receptor family cloning, functional expression and localization. FEBS Lett, 1994, 341:33-38
4. Bunzow JR, Saez C, Mortrud M, et al. Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ or κ opioid receptor type. FEBS Lett, 1994, 347: 284-288
5. Rossi GC, Leventhal L, Bolan EA, et al. Orphanin/FQ or nociceptin: evidence for analgesia and hyperalgesia in the CD-1 mouse. 27th meeting of the international narcotics research conference. California, USA, July, 1996
6. Vanderah TW, Lashbrook J, Horvath R, et al. Orphanin FQ/Nociceptin (OFQ/N) and sensory thresholds in mice or rats. 27th meeting of the international narcotics research conference. California, USA, July, 1996
7. Noble F, Montiel JL, Cornille F, et al. Pharmacological study of orphanin: role in the pain control. 27th meeting of the international narcotics research conference, California, USA, July, 1996
8. Yang HL, Luo RS, Wang LX, et al. Primary structure and disulfide bridge location of arrowhead double-headed proteinase inhibitors. J Biochem , 1992, 111: 537-545
9. Zhu CB, Liu YH, Xu SF. Increase in opioid receptor binding sites in rat brain during acupuncture analgesia enhanced by droperidol: an autoradiographic study. Chin J Neurosic, 1995, 2: 7-13
10. Florin S, Suaudeau C, Mollereau C, et al. Effects of icv - administered nociceptins on nociception, locomotion and curiosity in mice. 27th meeting of the international narcotics research conference, California, USA, July, 1996
11. Grisel JE, Mogil JS, Hunter MA, et al. Orphanin FQ is an anti-opioid peptide. 27th meeting of the international narcotics research conference, California, USA, July, 1996
12. Zhang YZ, Mulder H, Chang J-K. et al. Orphanin FQ/Nociceptin and its mRNA in rat spinal cord. 27th meeting of the international narcotics research conference, California, USA, July, 1996