Orienting gaze shifts during muscimol inactivation of caudal fastigial nucleus in the cat. II. Dynamics and eye-head coupling

Journal of Neurophysiology

Volumn 79, Issue 4, 1998, Pages 1959-1976

  Goffart, Laurent ^a,b   Pélisson, Denis ^a,c   Guillaume, Alain ^a  

^a Espace et Action   (France)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ARTICLE; CONTROLLED STUDY; COORDINATION; DYNAMICS; DYSMETRIA; EYE MOVEMENT; FASTIGIAL NUCLEUS; GAZE; HEAD MOVEMENT; NONHUMAN; PRIORITY JOURNAL;

EID: 2642650339     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1998.79.4.1959     Document Type: Article

References (97)

1. ASCHOFF, J. C. AND COHEN, B. Changes in saccadic eye movements produced by cerebellar cortical lesions. Exp. Neurol. 32: 123-133, 1971.
2. BATINI, C., BUISSERET-DELMAS, C., CORVISIER, J., HARDY, O., AND JASSIK-GERSCHENFELD, D. Brain stem nuclei giving fibers to lobules VI and VII of the cerebellar vermis. Brain Res. 153: 241-261, 1978.
3. BATINI, C., BUISSERET, P., AND KADO, R. T. Extraocular proprioceptive and trigeminal projections to the Purkinje cells of the cerebellar cortex. Arch. Ital. Biol. 112: 1-17, 1974.
4. BERTHOZ, A. AND LLINAS, R. Afferent neck projection to the cat cerebellar cortex. Exp. Brain Res. 20: 385-401, 1974.
5. BHAROS, T. B., KUYPERS, H.G.J.M., LEMON, R. N., AND MUIR, R. B. Divergent collaterals from deep cerebellar neurons to thalamus and tectum, and to medulla oblongata and spinal cord: retrograde fluorescent and electrophysiological studies. Exp. Brain Res. 42: 399-410, 1981.
6. BLANKS, R.H.I. Cerebellum. In: Neuroanatomy of the Oculomotor System, edited by J. A. Büttner-Ennever. Amsterdam: Elsevier, 1988, p. 255-272.
7. BRODAL, P., DIETRICHS, E., AND WALBERG, F. Do pontocerebellar mossy fibres give off collaterals to the cerebellar nuclei? An experimental study in the cat with implantation of crystalline HRP-WGA. Neurosci. Lett. 4: 12-24, 1986.
8. BURDE, R. M., STROUD, M. H., ROPER-HALL, G., WIRTH, F. P., AND O'LEARY, J. Ocular motor dysfunction in total and hemicerebellectomized monkeys. Br. J. Ophthalmol. 59: 560-565, 1975.
9. CARPENTER, M. B. AND BATTON, R. R. Connections of the fastigial nucleus in the cat and monkey. In: The Cerebellum-New Vistas, edited by S. L. Palay and V. Chan-Palay. Berlin: Springer-Verlag, 1982, p. 250-295.
10. COHEN, B., GOTO, K., SHANZER, S., AND WEISS, A. H. Eye movements induced by electrical stimulation of the cerebellum in the alert cat. Exp. Neurol. 13: 145-162, 1965.
11. COHEN, B. AND KOMATSUZAKI, A. Eye movements induced by stimulation of the pontine reticular formation: evidence for integration in oculomotor pathways. Exp. Neurl. 36: 101-117, 1972.
12. COWIE, R. J. AND ROBINSON, D. L. Subcortical contributions to head movements in macaques. I. Contrasting effects of electrical stimulation of a medial pontomedullary region and the superior colliculus. J. Neurophysiol. 72: 2648-2664, 1994.
13. CROMMELINCK, M. AND ROUCOUX, A. Characteristics of cat's eye saccades in different states of alertness. Brain Res. 103: 574-578, 1976.
14. CULLEN, K. E., GUITTON, D., REY, C. G., AND JIANG, W. Gaze-related activity of putative inhibitory burst neurons in the head-free cat. J. Neurophysiol. 70: 2678-2683, 1993.
15. DEAN, P. Modelling the role of the cerebellar fastigial nuclei in producing accurate saccades: the importance of burst timing. Neuroscience 68: 1059-1077, 1995.
16. DIETRICHS, E. AND WALBERG, F. Cerebellar nuclear afferents - where do they originate? A re-evaluation of the projections from some lower brainstem nuclei. Anat. Embryol. 177: 165-172, 1987.
17. DONALDSON, I.M.L. AND HAWTHORNE, M. E. Coding of visual information by units in the cat cerebellar vermis. Exp. Brain Res. 34: 27-48, 1979.
18. DREW, T. AND ROSSIGNOL, S. Functional organization within the medullary reticular formation of intact unanesthetized cat. I. Movements evoked by microstimulation. J. Neurophysiol. 64: 767-781, 1990.
19. FREEDMAN, E. G. AND SPARKS, D. L. Eye-head coordination during head unrestrained gaze shifts in rhesus monkeys. J. Neurophysiol. 77: 2328-2348, 1997a.
20. FREEDMAN, E. G. AND SPARKS, D. L. Activity of cells in the deeper layers of the superior colliculus of the rhesus monkey: evidence for a gaze displacement command. J. Neurophysiol. 78: 1669-1690, 1997b.
21. FREEDMAN, E. G., STANFORD, T. R., AND SPARKS, D. L. Combined eye-head gaze shifts produced by electrical stimulation of the superior colliculus in rhesus monkeys. J. Neurophysiol. 76: 927-952, 1996.
22. FREEMAN, J. A. Response of cat cerebellar Purkinje cells to convergent inputs from cerebral cortex and peripheral sensory systems. J. Neurophysiol. 33: 697-712, 1970.
23. FUCHS, A. F., ROBINSON, F. R., AND STRAUBE, A. Role of the caudal fastigial nucleus in saccade generation. I. Neuronal discharge patterns. J. Neurophysiol. 70: 1712-1740, 1993.
24. FUJIKADO, T. AND NODA, H. Saccadic eye movements evoked by microstimulation of lobule VII of cerebellar vermis of macaque monkeys. J. Physiol. (Lond.) 394: 573-594, 1987.
25. FUKUSHIMA, K., PETERSON, B. W., UCHINO, Y., COULTER, J. D., AND WILSON V. J. Direct fastigiospinal fibers in the cat. Brain Res. 126: 538-542, 1977.
26. GERRITS, N. M. AND VOOGD, J. The projection of the nucleus reticularis tegmenti pontis and adjacent regions of the pontine nuclei to the central cerebellar nuclei in the cat. J. Comp. Neurol. 258: 52-69, 1987.
27. GOFFART, L. AND PÉLISSON, D. Orienting gaze shifts during muscimol inactivation of caudal fastigial nucleus in the cat. I. Gaze dysmetria. J. Neurophysiol. 79: 1942-1958, 1998.
28. GOLDBERG, M. E., MUSIL, S. Y., FITZGIBBON, E. J., SMITH, M., AND OLSON, C. R. The role of the cerebellum in the control of saccadic eye movements. In: Role of the Cerebellum and Basal Ganglia in Voluntary Movements, edited by N. Mano, I. Hamada, and M. R. DeLong. Amsterdam: Elsevier, 1993, p. 203-211.
29. GOULD, B. B. Organization of afferents from the brainstem nuclei to the cerebellar cortex in the cat. Adv. Anat. Embryol. Cell Biol. 62: 1-90, 1980.
30. GRANTYN, A. AND BERTHOZ, A. Reticulo-spinal neurons participating in the control of synergic eye and head movements during orienting in the cat. I. Behavioral properties. Exp. Brain Res. 66: 339-354, 1987.
31. GRANTYN, A., BERTHOZ, A., HARDY, O., AND GOURDON, A. Contribution of reticulospinal neurons to the dynamic control of head movements: Presumed neck bursters. In: Head-Neck Sensory-Motor System, edited by A. Berthoz, W. Graf, and P. P. Vidal, New York: Oxford, 1992a, p. 318-329.
32. GRANTYN, A., HARDY, O., OLIVIER, E., AND GOURDON, A. Relationships between task-related discharge patterns and axonal morphology of brainstem projection neurons involved in orienting eye and head movements. In: Vestibular and Brain Stem Control of Eye, Head and Body Movements, edited by H. Shimazu and Y. Shinoda. Basel: Karger, 1992b, p. 255-273.
33. GRUART, A. AND DELGADO-GARCIA, J. M. Signalling properties of identified deep cerebellar nuclear neurons related to eye and head movements in the alert cat. J. Physiol. (Lond.) 478: 1:37-54, 1994.
34. GUITTON, D. Control of eye-head coordination during gaze shifts. Trends Neurosci. 15: 174-179, 1992.
35. GUITTON, D. AND MANDL, G. Frontal "oculomotor" area in alert cat. II. Unit discharges associated with eye movements and neck muscle activity. Brain Res. 149: 313-327, 1978.
36. GUITTON, D., MUNOZ, D. P., AND GALIANA, H. L. Gaze control in the cat: studies and modelling of the coupling between orienting eye and head movements in different behavioral tasks. J. Neurophysiol. 64: 509-531, 1990.
37. HARTING, J. K., UPDYKE, B. V., AND VAN LIESHOUT D. Corticotectal projections in the cat: anterograde transport studies of twenty-five cortical areas. J. Comp. Neurol. 324: 379-414, 1992.
38. HASHIMOTO, M. AND OHTSUKA, K. Transcranial magnetic stimulation over the posterior cerebellum during visually guided saccades in man. Brain 118: 1185-1193, 1995.
39. HELMCHEN, C., STRAUBE, A., AND BÜTTNER, U. Saccade-related activity in the fastigial oculomotor region of the macaque monkey during spontaneous eye movements in light and darkness. Exp. Brain Res. 98: 474-482, 1994.
40. HEPP, K., HENN, V., AND JAEGER, J. Eye movement related neurons in the cerebellar nuclei of the alert monkey. Exp. Brain Res. 45: 253-264, 1982.
41. HIRAI, T., ONODERA, S., AND KAWAMURA, K. Cerebellotectal projections studied in cats with horseradish peroxidase or tritiated amino acids axonal transport. Exp. Brain Res. 48: 1-12, 1982.
42. HOMMA, Y., NONAKA, S., MATSUYAMA, K., AND MORI, S. Fastigiofugal projection to the brainstem nuclei in the cat: an anterograde PHA-L tracing study. Neurosci. Lett. 23: 89-102, 1995.
43. ISA, T. AND SASAKI, S. Effects of lesion of the paramedian pontomedullary reticular formation by kainic acid injection on the visually triggered horizontal orienting movements in the cat. Neurosci. Lett. 87: 233-239, 1988.
44. IWAMOTO, Y. AND SASAKI, S. Monosynaptic excitatory connexions of reticulospinal neurones in the nucleus reticularis pontis caudalis with dorsal neck motoneurones in the cat. Exp. Brain. Res. 80: 277-289, 1990.
45. JÜRGENS, R., BECKER, W., AND KORNHÜBER, H. H. Natural and drug-induced variations of velocity and duration of human saccadic eye movements: evidence for a control of the neural pulse generator by local feedback. Biol. Cybern. 39: 87-96, 1981.
46. KANEKO, C.R.S., EVINGER, C., AND FUCHS, A. F. Role of cat pontine burst neurons in generation of saccadic eye movements. J. Neurophysiol. 46: 387-408, 1981.
47. KAWAMURA, S., HATTORI, S., HIGO, S., AND MATSUYAMA, T. The cerebellar projections to the superior colliculus and pretectum in the cat: an autoradiographic and horseradish peroxidase study. Neuroscience 7: 1673-1689, 1982.
48. KELLER, E. L. The cerebellum. In: The Neurobiology of Saccadic Eye Movements, edited by R. H. Wurtz and M. E. Goldberg. Amsterdam: Elsevier, 1989, p. 391-411.
49. KELLER, E. L., SLAKEY, D. P., AND CRANDALL, W. F. Microstimulation of the primate cerebellar vermis during saccadic eye movements. Brain Res. 288: 131-143, 1983.
50. KOTCHABHAKDI, N. AND WALBERG, F. Primary vestibular afferent projections to the cerebellum as demonstrated by retrograde transport of horseradish peroxidase. Brain Res. 142: 142-146, 1978.
51. KYUHOU, S. I. AND KAWAGUCHI, S. Cerebellocerebral projection from the fastigial nucleus onto the frontal eye field and anterior ectosylvian visual area in the cat. J. Comp. Neurol. 259: 571-590, 1987.
52. LAURUTIS, V. P. AND ROBINSON, D. A. The vestibulo-ocular reflex during human saccadic eye movements. J. Physiol. (Lond.) 373: 209-233, 1986.
53. MATSUSHITA, M. AND HOSOYA, Y. The location of spinal projection neurons in the cerebellar nuclei (cerebellospinal tract neurons) in the cat. A study with the horseradish peroxydase technique. Brain Res. 142: 237-248, 1978.
54. MAY, P. J., HARTWICH-YOUNG, R., NELSON, J. S., SPARKS, D. L., AND PORTER, J. D. Cerebellotectal pathways in the macaque: implications for collicular generation of saccades. Neuroscience 36: 305-324, 1990.
55. MAYS, L. E. AND SPARKS, D. L. Saccades are spatially, not retinocentrically, coded. Science 208: 1163-1165, 1980.
56. MOSCHOVAKIS, A. K. Neural network simulations of the primate oculomotor system. I. The vertical saccadic burst generator. Biol. Cybern. 70: 291-302, 1994.
57. MUNOZ, D. P., GUITTON, D., AND PÉLISSON, D. Control of orienting gaze shifts by the tecto-reticulo-spinal system in the cat whose head is unrestrained. III. Spatio-temporal characteristics of phasic motor discharges. J. Neurophysiol. 66: 1642-1666, 1991.
58. NODA, H., MURAKAMI, S., AND WARABI, T. Effects of fastigial stimulation upon visually-directed saccades in macaque monkeys. Neurosci. Res. 10: 188-199, 1991.
59. NODA, H., MURAKAMI, S., YAMADA, J., TAMAKI, J., AND ASO, T. Saccadic eye movements evoked by microstimulation of the fastigial nucleus of macaque monkeys. J. Neurophysiol. 60: 1036-1052, 1988.
60. NODA, H., SUGITA, S., AND IKEDA, Y. Afferent and efferent connections of the oculomotor region of the fastigial nucleus in the macaque monkey. J. Comp. Neurol. 302: 330-348, 1990.
61. OHTSUKA, K. AND NODA, H. Saccadic burst neurons in the oculomotor region of the fastigial nucleus of macaque monkeys. J. Neurophysiol. 65: 1422-1434, 1991.
62. OHTSUKA, K. AND NODA, H. Discharge properties of Purkinje cells in the oculomotor vermis during visually guided saccades in the macaque monkey. J. Neurophysiol. 74: 1828-1840, 1995.
63. OHTSUKA, K., SATO, H., AND NODA, H. Saccadic burst neurons in the fastigial nucleus are not involved in compensating for orbital nonlinearities. J. Neurophysiol. 71: 1976-1980, 1994.
64. OPTICAN, L. M. Saccadic dysmetria. In: Functional Basis of Ocular Motility Disorders, edited by G. Lennerstrand, D. S. Zee, and E. L. Keller. Oxford, UK: Pergamon Press, 1982, p. 441-451.
65. OPTICAN, L. M. AND ROBINSON, D. A. Cerebellar-dependent adaptive control of primate saccadic system. J. Neurophysiol. 44: 1058-1076, 1980.
66. PARÉ, M., CROMMELINCK, M. AND GUITTON, D. Gaze shifts evoked by stimulation of the superior colliculus in the head-free cat conform to the motor map but also depend on stimulus strength and fixation activity. Exp. Brain Res. 101: 123-129, 1994.
67. PÉLISSON, D. AND GOFFART, L. Visuo-motor transformation deficits after inactivation of the caudal fastigial nucleus in the head-free cat. Soc. Neurosci. Abstr. 502: 1270, 1995.
68. PÉLISSON, D., PRABLANC, C., AND URQUIZAR, C. Vestibuloocular reflex inhibition and gaze saccade control characteristics during eye-head orientation in humans. J. Neurophysiol. 59: 997-1013, 1988.
69. PETERSON, B. W. Identification of reticulospinal projections that may participate in gaze control. In: Control of Gaze by Brain Stem Neurons, Developments in Neuroscience, edited by R. Baker and A. Berthoz. Amsterdam: Elsevier, 1977, p. 143-152.
70. PETERSON, B. W., PITTS, N. G., FUKUSHIMA, K., AND MACKEL, R. Reticulospinal excitation and inhibition of neck motoneurons. Exp. Brain Res. 32: 471-489, 1978.
71. PHILLIPS, J. O., LING, L., FUCHS, A. F., SIEBOLD, C., AND PLORDE, J. J. Rapid horizontal gaze movement in the monkey. J. Neurophysiol. 73: 1632-1652, 1995.
72. RHO, M. J., CABANA, T., AND DREW, T. A retrograde transport study of the connections between the cerebellar nuclei and the medullary reticular formation in the cat. Soc. Neurosc. Abstr. 640-12: 1631, 1996.
73. RITCHIE, L. Effects of cerebellar lesions on saccadic eye movements. J. Neurophysiol. 39: 1246-1256, 1976.
74. ROBINSON, D. A. Oculomotor control signals. In: Basic Mechanisms of Ocular Motility and Their Clinical Implications, edited by G. Lennerstrand and P. Bach-Y-Rita. Oxford: Pergamon Press, 1975, p. 337-378.
75. ROBINSON, F. R. Role of the cerebellum in movement control and adaptation. Curr. Opin. Neurobiol. 5: 755-762, 1995.
76. ROBINSON, F. R., STRAUBE, A., AND FUCHS, A. F. Role of the caudal fastigial nucleus in saccade generation. II. Effects of muscimol inactivation. J. Neurophysiol. 70: 1741-1758, 1993.
77. ROLDAN, M. AND REINOSO-SUAREZ, F. Cerebellar projections to the superior colliculus in the cat. J. Neurosci. 1: 827-834, 1981.
78. ROUCOUX, A., GUITTON, D., AND CROMMELINCK, M. Stimulation of the superior colliculus in the alert cat. II. Eye and head movements evoked when the head is unrestrained. Exp. Brain Res. 39: 75-85, 1980.
79. SATO, H. AND NODA, H. Saccadic dysmetria induced by transient functional decortication of the cerebellar vermis. Exp. Brain Res. 88: 455-458, 1992.
80. SCHWARTZ, D.W.F. AND TOMLINSON, R. D. Neuronal responses to eye muscle stretch in cerebellar lobule VI of the cat. Exp. Brain Res. 27: 101-111, 1977.
81. SEGAL, R. L., BECKSTEAD, R. M., KERSEY, K., AND EDWARDS, S. B. The prefrontal corticotectal projection in the cat. Exp. Brain Res. 51: 423-432, 1983.
82. SEGRAVES, M. A. AND GOLDBERG, M. E. Properties of eye and head movements evoked by electrical stimulation of the monkey superior colliculus. In: Head-Neck Sensory-Motor System, edited by A. Berthoz, W. Graf, and P. P. Vidal. New York: Oxford, 1992, p. 292-295.
83. SHIMIZU, N., MIZUNO, M., NAITO, M., AND YOSHIDA, M. The interaction between accuracy of gaze with and without head movements in patients with cerebellar ataxia. Ann. NY Acad. Sci. 374: 579-589, 1981a.
84. SHIMIZU, N., NAITO, M., AND YOSHIDA, M. Eye-head co-ordination in patients with parkinsonism and cerebellar ataxia. J. Neurol. Neurosurg. Psych. 44: 509-515, 1981b.
85. SIEGEL, J. M. AND TOMASZEWSKI, K. S. Behavioral organization of reticular formation: studies in the unrestrained cat. I. Cells related to axial, limb, eye, and other movements. J. Neurophysiol. 50: 696-71, 1983.
86. STERIADE, M. Two channels in the cerebellothalamocortical system. J. Comp. Neurol. 354: 57-70, 1995.
87. STRAUBE, A. AND DEUBEL, H. Rapid gain adaptation affects the dynamics of saccadic eye movements in humans. Vision Res. 35: 3451-3458, 1995.
88. SUGIMOTO, T., MIZUNO, N., AND UCHIDA, K. Distribution of cerebellar fiber terminals in the midbrain visuomotor areas: an autoradiographic study in the cat. Brain Res. 238: 353-370, 1982.
89. SUZUKI, S. S., SIEGEL, J. M., AND WU, M. F. Role of pontomedullary reticular formation neurons in horizontal head movements: an ibotenic acid lesion study in the cat. Brain Res. 484: 78-93, 1989.
90. TOMLINSON, R. D. Combined eye-head gaze shifts in the primate. III. Contributions to the accuracy of gaze saccades. J. Neurophysiol. 64: 1873-1891, 1990.
91. TORTELLY, A. F., REINOSO-SUAREZ F., AND LLAMAS A. Projections from non-visual cortical areas to the superior colliculus demonstrated by retrograde transport of HRP in the cat. Brain Res. 188: 543-549, 1980.
92. VAN DER WANT, J.J.L., GERRITS, N. M., AND VOOGD, J. Autoradiography of mossy fiber terminals in the fastigial nucleus of the cat. J. Comp. Neurol. 258: 70-80, 1987.
93. VIDAL, P. P., CORVISIER, J., AND BERTHOZ, A. Eye and neck motor signals in periabducens reticular neurons of the alert cat. Exp. Brain Res. 53: 16-28, 1983.
94. VILIS, T. AND HORE, J. Characteristics of saccadic dysmetria in monkeys during reversible lesions of medial cerebellar nuclei. J. Neurophysiol. 46: 828-838, 1981.
95. WESTHEIMER, G. AND BLAIR, S. M. Functional organization of primate oculomotor system revealed by cerebellectomy. Exp. Brain Res. 21: 463-472, 1974.
96. YOSHIDA, K., MCCREA, R. A., BERTHOZ, A., AND VIDAL, P. P. Morphological and physiological characteristics of inhibitory burst neurons controlling horizontal rapid eye movements in the alert cat. J. Neurophysiol. 48: 761-784, 1982.
97. ZEE, D. S., OPTICAN, L. M., COOK, J. D., ROBINSON, D. A., AND ENGEL, W. K. Slow saccades in spinocerebllar degeneration. Arch. Neurol. 33: 243-251, 1976.