Participation of factor B in residual immune complex red cell binding activity observed in serum from a C2-deficient systemic lupus erythematosus patient may delay the appearance of clinical symptoms

Arthritis and Rheumatism

Volumn 41, Issue 3, 1998, Pages 427-434

  Traustadóttir, Kristin H ^a   Rafnar, Bjarni O ^a   Steinsson, Kristján ^a   Valdimarsson, Helgi ^a   Erlendsson, Kristján ^a  

^a LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C2;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; BASE PAIRING; COMPLEMENT DEFICIENCY; COMPLEMENT SYSTEM; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; ERYTHROCYTE MEMBRANE; GENE DELETION; HUMAN; HUMAN CELL; PLASMA TRANSFUSION; PRIORITY JOURNAL; REMISSION; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 2642641297     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(199803)41:3<427::AID-ART8>3.3.CO;2-Z     Document Type: Article

References (25)

1. Atkinson JP. Complement deficiency: predisposing factor to auto-immune syndromes. Am J Med 1988;85:45-7.
2. Agnello V. Complement deficiency states. Medicine (Baltimore) 1978;57:1-23.
3. Awdeh ZL, Raum DD, Glass D, Agnello V, Schur PH, Johnston RB, et al. Complement-human histocompatibility antigen haplo-types in C2 deficiency. Cell Immunol 1981;67:581-3.
4. Walport MJ. Complement deficiency and disease. Br J Rheumatol 1993;32:269-73.
5. Truedson L, Alper CA, Awdeh ZL, Johansen P, Sjoholm AG, Sturfelt G. Characterization of type I complement C2 deficiency MHC haplotypes. J Immunol 1993;151:5856-63.
6. Ruddy S. Component deficiencies. 3. The second component. Prog Allergy 1986;39:250-66.
7. Rynes RI. Inherited complement deficiency states and SLE. Clin Rheum Dis 1982;8:29-47.
8. Steinsson K, Erlendsson K, Valdimarsson H. Successful plasma infusion treatment of a patient with C2 deficiency and systemic lupus erythematosus: clinical experience over forty-five months. Arthritis Rheum 1989;32:906-13.
9. Erlendsson K, Traustadóttir K, Freysdottir J, Steinsson K, Jonsdottir I, Valdimarsson H. Reciprocal changes in complement activity and immune-complex levels during plasma infusion in a C2 deficient SLE patient. Lupus 1993;2:161-5.
10. Steuer KLK, Sloan LB, Oglesby TJ, Farries TC, Nickells MW, Densen P, et al. Lysis of sensitized sheep erythrocytes in human sera deficient in the second component of complement. J Immunol 1989;143:2256-61.
11. Farries TC, Steuer LK, Atkinson JP. The mechanism of activation of the alternative pathway of complement by cell-bound C4b. Mol Immunol 1990;27:1155-61.
12. May JE, Frank MM. Hemolysis of sheep erythrocytes in guinea pig serum deficient in the fourth component of complement. II. Evidence for involvement of C1 and components of the alternate complement pathway. J Immunol 1973;111:1668-76.
13. Davies KA, Erlendsson K, Beynon HL, Peters AM, Steinsson K, Valdimarsson H, et al. Splenic uptake of immune complexes in man is complement-dependent. J Immunol 1993;151:3866-73.
14. Garred P, Mollnes TE, Thorsteinsson L, Erlendsson K, Steinsson K. Increased amounts of C4-containing immune-complexes and inefficient activation of C3 and the terminal complement pathway in a patient with homozygous C2 deficiency and systemic lupus erythematosus. Scand J Immunol 1990;31:59-64.
15. Milford-Ward A. Immunoprecipitation in the evaluation of the proteins in plasma and body fluid. In: Thompson RA, editor. Techniques in clinical immunology. 2nd ed. London: Blackwell Scientific Publications; 1981. p. 9.
16. Parham P. Preparation and purification of active fragments from mouse monoclonal antibodies. In: Weir DM. editor. Handbook of experimental immunology: immunochemistry 1. Oxford: Blackwell Scientific Publications: 1986. p. 11.
17. Mollnes TE. Quantification of the C3d split products of human complement by a sensitive enzyme-linked immunosorbent assay. Scand J Immunol 1985;21:607-13.
18. Avrameas S, Ternynck T, Guesdon J-L. Coupling of enzymes to antibodies and antigens. Scand J Immunol 1978;8:7-23.
19. Schifferli JA, Ng YC, Peters DK. The role of complement and its receptor in the elimination of immune complexes. N Engl J Med 1986;315:488-95.
20. Cornacoff JB, Herbert LA, Smead WL, Vanaman ME, Birmingham DJ, Waxman FJ. Primate erythrocyte-immune complex-clearing mechanism. J Clin Invest 1983;71:236-47.
21. Schifferli JA, Bartolotti SR, Peters DK. Inhibition of immune precipitation by complement. Clin Exp Immunol 1980;42:387-94.
22. Frank MM, Fries LF. The role of complement in inflammation and phagocytosis. Immunol Today 1991;12:322-6.
23. Morgan BP, Walport MJ. Complement deficiency and disease. Immunol Today 1991;12:301-6.
24. Farries TC, Steuer KLK, Atkinson JP. Evolutionary implications of a new bypass activation pathway of the complement system. Immunol Today 1990;11:78-80.
25. Truedson L, Gullstrand B, Jonson T, Klint C. Serum concentrations of C4 isotypes and factor B in type I C2 deficiency suggest haplotype-dependent quantitative expression of MHC class III complement genes. Exp Clin Immunogenet 1995;12:66-73.