Concentration of copper and zinc in blood of psoriatic patients treated topically with ointment containing 2-chloroethyl-3-chloropropyl sulfide

Polish Journal of Pharmacology

Volumn 50, Issue 1, 1998, Pages 47-53

  Kopff, Maria ^a   Wołkanin, Piotr ^a   Strzelczyk, Marek ^a   Mirosław, Witold ^a   Borkowski, Arkadiusz ^b   Puczkowski, Sławomir ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b MILITARY HOSPITAL   (Poland)

Author keywords

2 chloroethyl 3 chloropropyl sulfide; Blood; Copper; Erythrocytes; Plasma; Psoriasis; Zinc

Indexed keywords

(2 CHLOROETHYL) (3 CHLOROPROPYL) SULFIDE; COPPER; SULFIDE; UNCLASSIFIED DRUG; ZINC;

ADULT; AGED; CONTROLLED STUDY; COPPER BLOOD LEVEL; DATA ANALYSIS; DRUG BLOOD LEVEL; ENZYME ACTIVITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PSORIASIS; SHORT SURVEY; TOPICAL DRUG ADMINISTRATION; TREATMENT PLANNING; ZINC BLOOD LEVEL;

ADMINISTRATION, TOPICAL; ADOLESCENT; ADULT; AGED; COPPER; DERMATOLOGIC AGENTS; ERYTHROCYTES; FEMALE; HUMANS; MALE; MIDDLE AGED; PSORIASIS; SULFIDES; ZINC;

EID: 2642619429     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (32)

1. Burley R. W., De Kock W. J.: N-terminal amino acid residues in whool blood from normal and copper - deficient sheep. Arch. Biochem., 1957, 68, 21-29.
2. Catalog a NMR & IR. Ed. Sadler Research Laboratories, Philadelphia, 1986, 70517K, 43026M.
3. Consent of Committee for Supervision of Experiments Conducted on Human Beings, No 686 dated on 12.02.1992.
4. De-Simone C., De-Sole P., Di-Mario G., Veniev A., Cermie Le D., Serri R: Reactive oxygen species production in circulating polymorphonuclear leukocytes in psoriasis. Acta Derm. Venereol., (Stockh.) Suppl., 1989, 146, 50-52.
5. Dogan P., Soyuer U., Tanrikulu G.: Superoxide dismutase and myeloperoxidase activity in polymorphonuclear leucocytes, and serum ceruloplasmin and copper levels, in psoriasis. Brit. J. Dermatol., 1989, 120, 239-244.
6. Dreno B., Vandermeeren M. A., Boiteau H. L., Stalder J. F., Barriere H.: Plasma zinc is decreased only in generalized pustular psoriasis. Dermatologica, 1986, 173, 209-212.
7. Elsayed N. M., Ta P. N., Korte D. W.: Biochemical alterations in mouse liver induced by nitrogen mustard. Toxicologist, 1989, 9, 26-33.
8. Endre L., Katara Z., Gyurkovits K.: Zinc deficiency and cellular immune deficiency in acrodermatitis enteropatica. Lancet, 1975, 11, 1196.
9. Heilmeyer L., Kinderling W., Stuwe G.: Kupfer und Eisen als körpereigene Wirkstoffe und ihre Bedeutung beim Krankheitsgeschehen. Fischer, Jena, 1979.
10. Kekki M., Koskelo P., Lassus A.: Serum ceruloplasmin-bound copper and non-ceruloplasmin copper in uncomplicated psoriasis. J. Invest. Dermatol., 1966, 47, 159-166.
11. 14C] butyl 2-chloroethyl sulfide in the rat. J. Toxicol., 1988, 7, 255-261.
12. Kopff M., Zakrzewska I., Strzelczyk M., Klem J., Dubiecki W.: Superoxide dismutase and catalase activity in psoriatic patients treated topically with ointment containing 2-chloroethyl-3-chloropropyl sulfide. Pol. J. Pharmacol., 1994, 46, 439-444.
13. Lipkin G., Herrman F., Mandol L.: Studies on serum copper. I. The copper content of blood serum in patients with psoriasis. J. Invest. Dermatol., 1962, 39, 543-546.
14. Lutz R. E.: The normal occurence of zinc in biological materials : a review of the literature and a study of normal distribution of zinc in the rat, cat and man. J. Industr. Hyg., 1926, 8, 177-207.
15. Michaelsson G., Ljunghall K.: Patients with dermatitis herpetiformis, acne, psoriasis and Darier's disease have low epidermal zinc concentration. Brit. J. Dermatol., 1980, 102, 579-585.
16. Miyachi Y., Niwa Y.: Effects of psoriatic sera on the generation of oxygen intermediates by normal polymorphonuclear leucocytes. Arch. Dermatol. Res., 1983, 275, 23-26.
17. Molokhia M. M., Portnoy B.: Neutron activation analysis of trace elements in skin. V. Copper and zinc in psoriasis. Brit. J. Dermatol., 1970, 83, 376-381.
18. Pories W.J., Strain W.H.: Zinc wound healing. In: Zinc Metabolism. Ed. Prasad A. S., Springfdield, Charles C. Thomas, 1966, 378-394.
19. Prasad A. S.: Clinical, endocrinlogical and biochemical effects of zinc deficiency. Clin. Endocrinol. Metabol., 1985, 14, 567-589.
20. Prasad A. S.: Clinical manifestation of zinc deficiency. Annu. Rev. Nutr., 1985, 341-363.
21. Slater T. F.: Free-radical mechanism in tissue injury. Biochem. J., 1984, 22, 1-15.
22. Stróżyński H., Strzelczyk M., Ścianowski J.: Studies on mutagenicity of 3-chloropropyl sulfide derivatives, potential antipsoriatic agents. Pol. J. Pharmacol. Pharm., 1987, 39, 405-410.
23. Strzelczyk M., Dubiecki W., Rutkowski M.: Pol. Patent: P-281040, 1989.
24. Strzelczyk M., Dubiecki W., Rutkowski M., Klem J., Kopff M., Wołkanin P., Puczkowski S., Borkowski A., Zakrzewska I.: Preliminary clinical evaluation of new, original preparations: Psoriasol, Sulficyd, Ulcer-CLEPS (Polish). XXIX Zjazd Pol. Tow. Biochem., Wroclaw 15-17.09.1993, Abstracts, 486.
25. Strzelczyk M., Kotełko B.: Synthesis of hexahydro-1,4-thiazepine derivatives with expected pharmacological activity. Part I. N-Alkyl(hydroxyalkyl)-hexahydro-1,4-thiazepines and 2-(hexahydro-1,4-thiazepinyl)-ethyl esters of phenoxyacetic acids. Pol. J. Pharmacol. Pharm., 1979, 31, 73-82.
26. Strzelczyk M., Rutkowski M., Dubiecki W., Borkowski A., Gawlik J., Kopff M., Klem J., Wołkanin P., Puczkowski S., Stróżyński H., Ścianowski J., Kotełko B., Zakrzewska I., Białek J.: Antipsoriatic action of new, original preparation PSORIASOL - preliminary report (Polish). XXIV Zjazd Pol. Tow. Dermatol., Gdańsk 24-26.09.1992, Abstracts, 356.
27. Thune P.: Abnormally low plasma zinc levels in pustular psoriasis. Dermatologica, 1980, 161, 179-82.
28. Tripton I. H., Cook M. J.: Trace elements in human tissue. Part II. Adult subjects from the United States. Health Phys., 1963, 9, 103-145.
29. Vallee B. L., Galdes A.: The metallobiochemistry of zinc enzymes. Adv. Enzymol., 1984, 56, 283-430.
30. Wa̧sik F., Baran E., Walów B., Sierawska M., Waniewska I., Kaniowska E., Podwiński P., Andrzejak R. R.: Zinc level in leukocytes and serum of psoriatic patients in the period of active changes and remission in relation to chemotactic activity of polynuclear leukocytes (Polish). Przegl. Dermatol., 1985, 72, 237-242.
31. Wa̧sik F., Pelc W., Baran E., Paslawska A., Juźwiak I.: Zinc level in psoriatic patients in relation to the extent of skin (Polish). Przegl. Dermatol., 1980, 67, 333-336.
32. Zackheim H. S., Wolf P.: Serum copper in psoriasis and other dermatoses. J. Invest. Dermatol., 1972, 58, 28-32.