Stability of vancomycin in an extemporaneously compounded ophthalmic solution

American Journal of Health-System Pharmacy

Volumn 55, Issue 13, 1998, Pages 1386-1388

  Fuhrman Jr , L Clifton ^a   Stroman, Ronald T ^b  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b South Carolina Law Enforcement Division   (United States)

Author keywords

Antibiotics; Artificial tears; Compounding; Solutions, ophthalmic; Stability; Storage; Temperature; Vancomycin hydrochloride; Vehicles

Indexed keywords

ARTIFICIAL TEAR; BENZALKONIUM CHLORIDE; DEXTRAN 70; DRUG VEHICLE; EDETATE DISODIUM; EYE DROPS; HYDROXYPROPYLMETHYLCELLULOSE; TEARS NATURALE; VANCOMYCIN; WATER;

ARTICLE; CONTAINER; DRUG FORMULATION; DRUG STABILITY; DRUG STORAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; POWDER; PRIORITY JOURNAL; TEMPERATURE; TOPICAL DRUG ADMINISTRATION;

EID: 2642615410     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajhp/55.13.1386     Document Type: Article

References (7)

1. Baum L. Therapy for ocular bacterial infection. Trans Ophthalmol Soc U K. 1986; 105:69-77.
2. Blum RA, Rodvold KA. Recognition and importance of Staphylococcus epidermidis infections. Clin Pharm. 1987; 6:464-75.
3. The choice of antimicrobial drugs. Med Lett Drug Ther. 1988; 101:283-7.
4. Abate MA, Ross J. Topical vancomycin for the treatment of Staphylococcus epidermidis and methicillin-resistant Staphylococcus aureus conjunctivitis. DICP Ann Pharmacother. 1990; 24: 1050-2.
5. Osborn E, Baum JL, Ernst C et al. The stability of ten antibiotics in artificial tears solutions. Am J Ophthalmol. 1976; 82:775-80.
6. Brennan C, Muder R. Conjunctivitis associated with methicillin-resistant Staphylococcus aureus in a long-term-care facility. Am J Med. 1990; 88:5-14N-5-17N.
7. Riegelman S, Vaughn DG. A rational basis for the preparation of ophthalmic solutions. Surv Ophthalmol. 1958; 3:471-84.