Primary and tertiary structures of the Fab fragment of a monoclonal anti-E-selectin 7A9 antibody that inhibits neutrophil attachment to endothelial cells

Journal of Biological Chemistry

Volumn 273, Issue 19, 1998, Pages 11770-11775

  Rodríguez Romero, Adela ^a,b,d   Almog, Orna ^a   Tordova, Maria ^a   Randhawa, Zafar ^c,d   Gilliland, Gary L ^a,d  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c Otsuka Pharmaceuticals   (United States)

^d NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY 7A9; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBODY COMBINING SITE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENDOTHELIUM CELL; LEUKOCYTE ADHERENCE INHIBITION; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TERTIARY STRUCTURE; STEREOCHEMISTRY;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; BINDING SITES, ANTIBODY; CELL ADHESION; CRYSTALLOGRAPHY, X-RAY; E-SELECTIN; ENDOTHELIUM, VASCULAR; HL-60 CELLS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; INTERCELLULAR ADHESION MOLECULE-1; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEUTROPHILS; PROTEIN STRUCTURE, TERTIARY; RHINOVIRUS; SURFACE PROPERTIES;

MURINAE;

EID: 2642610266     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.19.11770     Document Type: Article

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