Modulation of epithelial differentiation by the E6 and E7 oncoproteins of human papillomaviruses

Radiation Oncology Investigations

Volumn 3, Issue 6, 1995, Pages 377-382

  Monini, Paolo ^a   Laimins, Laimonis A ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

keratinocytes; organotypic cultures; rafts; viral transformation

Indexed keywords

EID: 2642606165     PISSN: 10657541     EISSN: 15206823     Source Type: Journal    
DOI: 10.1002/roi.2970030624     Document Type: Article

References (24)

1. Heterogeneity of the human papillomavirus group
2. Impact of sexual habits on the clinical evaluation of male HPV infection
3. The human papilloma virus‐16 E7 oncoprotein is able to bind to the retinoblastoma gene product
4. HPV16 E7 oncoprotein deregulates B‐myb expression: Correlation with targeting of p107/ E2F complexes
5. E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
6. Human papillomavirus type 18 E7 protein requires intact cys‐X‐X‐Cys motifs for zinc binding, dimerization, and transformation but not for Rb binding
7. Mutational analysis of human papillomavirus type 16 E7 functions
8. p53 Cell cycle control and apoptosis: Implications for cancer
9. A cellular protein mediates the association of p53 with the E6 oncoprotein of human papillomavirus type 16 or 18
10. Inhibition of p53 DNA binding by human papillomavirus E6 protein
11. The HPV‐16 E6 and E6‐AP complex functions as a ubiquitin‐protein ligase in the ubiquitination of p53
12. Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53‐mediated repression of transcription
13. Human papillomavirus type 16 alters human epithelial cell differentiation in vitro
14. Progression of HPV 18 immortalized human keratinocytes to a malignant phenotype
15. In vitro differentiation of epithelial cells from cervical neoplasias resembles in vivo lesions
16. The E6‐E7 region of human papillomavirus type 18 is sufficient for transformation of NIH 3T3 and rat‐1 cells
17. Immortalization and altered differentiation of human keratinocytes in vitro by the E6 and E7 open reading frames of human papillomavirus type 18
18. Reconstruction of simplified skin‐control of fabrication
19. Retinoids as important regulators of terminal differentiation: Examining keratin expression in individual epidermal cells at various stages of keratinization
20. p53‐Dependent apoptosis produced by Rb‐deficiency in the developing mouse lens
21. The retinoblastoma tumor suppressor protein
22. Altered cell cycle regulation in the lens of HPV‐16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development
23. Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
24. Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV16 E7 gene in the presence or absence of p53