Phorbol myristate acetate downregulates the binding sites for colony- stimulating factor-1 on osteoclasts isolated from rats

Calcified Tissue International

Volumn 62, Issue 2, 1998, Pages 148-152

  Zhang, Z Y ^a   Muhlbauer R ^a   Felix, R ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Colony stimulating factor 1; Colony stimulating factor 1 receptor; Downregulation; Osteoclasts; Phorbol myristate acetate

Indexed keywords

4ALPHA PHORBOL DIDECANOATE; COLONY STIMULATING FACTOR 1; COLONY STIMULATING FACTOR RECEPTOR; CYCLOHEXIMIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN SYNTHESIS INHIBITOR;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; FEMUR; MACROPHAGE; NEWBORN; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOSARCOMA CELL; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION;

ANIMALS; ANIMALS, NEWBORN; BINDING SITES; CELLS, CULTURED; DOWN-REGULATION; FEMUR; IMMUNE SERA; MACROPHAGE COLONY-STIMULATING FACTOR; OSTEOCLASTS; RATS; TETRADECANOYLPHORBOL ACETATE;

EID: 2642595055     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002239900408     Document Type: Article

References (33)

1. Tushinski RJ, Oliver IT, Guilbert LJ, Tynan PW, Warner JR, Stanley ER (1982) Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy. Cell 28:71-81
2. Stanley ER (1994) Colony-stimulating factor-1 (macrophage colony-stimulating factor), In:Thomson A (ed) The cytokine handbook. Academic Press, London, pp 387-418
3. Felix R, Hofstetter W, Wetterwald A, Marco CG, Fleisch H (1994) Role of colony-stimulating factor-1 in bone metabolism. J Cell Biochem 55:340-349
4. Wiktor-Jedrzejczak W, Ahmed A, Szczylik C, Skelly RR (1982) Hematological characterization of congenital osteopetrosis in op/op mouse, J Exp Med 156:1516-1527
5. Marks SC Jr (1982) Morphological evidence of reduced bone resorption in osteopetrotic (op) mice, Am J Anat 163:157-167
6. Felix R, Cecchini MG, Hofstetter W, Elford PR, Stutzer A, Fleisch H (1990) Impairment of macrophage colony-stimulating factor production and lack of resident bone marrow macrophages in the osteopetrotic op/op mouse, J Bone Miner Res 5:781-789
7. Wiktor-Jedrzejczak W, Bartocci A, Ferrante AW, Ahmend-Ansari A, Sell KW, Pollard JW, Stanley ER (1990) Total absence of colony-stimulating factor I in the macrophage-deficient osteopetrotic (op/op) mouse. Proc Natl Acad Sci USA 87:4828-4832
8. Yoshida H, Hayashi S-I, Kunisada T, Ogawu M, Nishikawa S, Okamura H, Sudo T, Shultz LD, Nishikawa SI (1990) The murine mutation osteopetrosis is in the coding region of the macrophage colony-stimulating factor gene. Nature 345:442-444
9. Felix R, Cecchini MG, Fleisch H (1990) Macrophage colony-stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse. Endocrinology 127:2592-2594
10. Antonioli-Corboz V, Cecchini MG, Felix R, Fleisch H, van der Pluijm G, Löwik CWGM (1992) Effect of macrophage colony-stimulating factor on in vitro osteoclast generation and bone resorption. Endocrinology 130:437-442
11. 3. J Bone Miner Res 9:401-407
12. Takahashi N, Udagawa N, Akatsu T, Tanaka H, Isogal Y, Suda T (1991) Deficiency of osteoclasts in osteopetrotic mice is due to a defect in the local microenvironment provided by osteoblastic cells. Endocrinology 128:1792-1796
13. Tanaka S, Takahashi N, Udagawa N, Tamuru T, Akatsu T, Stanley ER, Kurokawa T, Suda T (1993) Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors. J Clin Invest 91:257-263
14. Hofstetter W, Wetterwald A, Cecchini MG, Felix R, Fleisch H, Mueller C (1992) Detection of transcripts for the receptor for macrophage colony-stimulating factor, c-fms, in murine osteoclasts. Proc Natl Acad Sci USA 89:9637-9641
15. Hofstetter W, Wetterwald A, Cecchini MG, Mueller C, Felix R (1995) Detection of transcripts and binding sites for colony-stimulating factor-1 during bone development. Bone 17:145-151
16. Weir EC, Horowitz MC, Baron R, Centrella M, Kucinski BM, Insogna KL (1993) Macrophage colony-stimulating factor release and receptor expression in bone cells. J Bone Miner Res 8:1507-1517
17. Fuller K, Owens JM, Jagger CJ, Wilson A, Moss R, Chambers TJ (1993) Macrophage colony-stimulating factor stimulates survival and chemotactic behavior in isolated osteoclasts. J Exp Med 178:1733-1744
18. Hattersley G, Dorey E, Horton MA, Chambers TJ (1988) Human macrophage colony-stimulating factor inhibits bone resorption by osteoclasts disaggregated from rat bone. J Cell Physiol 137:199-203
19. Li W, Stanley ER (1991) Role of dimerization and modification of the CSF-I receptor in its activation and internalization during the CSF-I response. The EMBO J 10:277-288
20. Chen BDM, Lin H-S, Hsu S (1983) Tumor-promoting phorbol esters inhibit the binding of colony-stimulating factor (CSF-I) to murine peritoneal exudate macrophages. J Cell Physiol 116:207-212
21. Nishizuka Y (1992) intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C. Science 258:607-614
22. Amano H, Hofstetter W, Cecchini MG, Fleisch H, Felix R (1995) Downregulation of colony-stimulating factor-1 (CSF-I) binding by CSF-I in isolated osteoclasts, Calcif Tissue int 57:367-370
23. Chambers TJ, Magnus CJ (1982) Calcitonin alters behaviour of isolated osteoclasts. J Pathol 136:27-39
24. Sahni M, Guenther HL, Fleisch H, Collin P, Martin TJ (1993) Bisphosphonates act on rat bone resorption through the mediation of osteoblasts. J Clin Invest 91:2004-2011
25. Tony HS, Sakai DD, Sims SM, Dixon SJ, Yamin M, Goldring SR, Sneud ML, Minkin C (1994) Murine osteoclasts and spleen cell polykaryons are distinguished by mRNA phenotyping. J Bone Miner Res 9:577-584
26. 125I-colony-stimulating factor with bone marrow-derived macrophages. J Biol Chem 261:4024-4032
27. Elford PR, Felix R, Cecchini M, Trechsel U, Fleisch H (1987) Murine osteoblast-like cells and the osteogenic cell MC3T3-E1 release macrophage colony-stimulating activity in culture. Calcif Tissue int 41:151-156
28. Felix R, Halasy-Nagy J, Wetterwald A, Cecchini MG, Fleisch H, Hofstetter W (1996) Synthesis of membrane- and matrix-bound colony stimulating factor-1 by cultured osteoblasts. J Cell Physiol 166:311-322
29. Hall TJ, Schaeublin M, Chambers TJ (1993) The majority of osteoclasts require mRNA and protein synthesis for bone resorption in vitro. Biochem Biophys Res Commun 195:1245-1253
30. Horiguchi J, Sariban E, Kufe D (1988) Transcriptional and posttranscriptional regulation of CSF-1 gene expression in human monocytes. Mol Cell Biol 8:3951-3954
31. Downing JR, Roussel MF, Sherr CJ (1989) Ligand and protein kinase C down-modulate the colony-stimulating factor 1 receptor by independent mechanisms. Mol Cell Biol 9:2890-2896
32. Baccarini M, Sbarbu PD, Buscher D, Burtocci A, Stanley ER (1992) IFN-r/lipopolysaccharide activation of macrophages is associated with protein kinase C-dependent downmodulation of the colony-stimulating factor-1 receptor, J Immunol 149:2656-2661
33. Su YJ, Chakraborty M, Nathanson MH, Baron R (1992) Differential effects of the 3′, 5′ -cyclic adenosine monophosphate and protein kinase C pathways on the response of isolated rat osteoclasts to calcitonin. Endocrinology 131:1497-1502