Simultaneous immunohistochemical and biochemical hormone receptor assessment in breast cancer provides complementary prognostic information

Anticancer Research

Volumn 17, Issue 6 D, 1997, Pages 4723-4729

  Biesterfeld, Stefan ^a   Schröder, Willibald ^a   Steinhagen, Gerrit ^a   Koch, Ralf ^a   Veuskens, Ursula ^a   Schmitz, Franz Josef ^b   Handt, Stefan ^a   Böcking, Alfred ^c  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Breast cancer; Estrogen; Hormone receptor; Image analysis; Immunohistochemistry; Progesterone; Survival rate

Indexed keywords

ESTROGEN RECEPTOR; HORMONE RECEPTOR; PARAFFIN; PROGESTERONE RECEPTOR;

ADULT; AGED; ARTICLE; BIOCHEMISTRY; BREAST CANCER; CANCER SURVIVAL; CONTROLLED STUDY; DIAGNOSTIC VALUE; FEMALE; FROZEN SECTION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DETERMINATION;

BREAST NEOPLASMS; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROGNOSIS; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; REPRODUCIBILITY OF RESULTS; SURVIVAL ANALYSIS;

EID: 2642591973     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Early Breast Cancer Trialists' Collaborative Group: Ovarian ablation in early breast cancer: overview of the randomized trials. Lancet 348: 1189-1196, 1996.
2. Allred DC, Bustamante A, Daniel OC, Gaskill HV, Cruz AB: Immunocytochemical analysis of estrogen receptors in human breast cancer. Arch Surg 125: 107-113, 1990.
3. Esteban JM, Ahn C, Battifora H, Felder B: Quantitative immunohistochemical assay for hormonal receptors: technical aspects and biological significance. J Cell Biochem (Suppl) 19: 138-145, 1994.
4. Esteban JM, Ahn C, Mehta P, Battifora H: Biologic significance of quantitative estrogen receptor immunohistochemical assay by image analysis in breast cancer. Am J Clin Pathol 102: 158-162, 1994.
5. Jonat W, Maass H, Stegner HE: Immunohistochemical measurement of estrogen receptors in breast cancer tissue samples. Cancer Res (Suppl) 46: 4296s-4298s, 1986.
6. Kinsel LB, Szabo E, Greene GL, Konrath J, Leight GS, McCarty KS: Immunocytochemical analysis of estrogen receptors as a predictor of prognosis in breast cancer patients: Comparison with quantitative biochemical methods. Cancer Res 49: 1052-1056, 1989.
7. Kommoss F, Pfisterer J, Idris T, Giese E, Sauerbrei W, Schafer W, Thome M, Pfleiderer A: Steroid receptors in carcinoma of the breast. Results of immunocytochemical and biochemical determination and their effects on short-term prognosis. Anal Quant Cytol Histol 16: 203-210, 1994.
8. Layfield LJ, Saria EA, Conlon DH, Kerns BJ: Estrogen and progesterone receptor status determined by the Ventana ES 320 automated immunohistochemical stainer and the CAS 200 image analyzer in 236 early-stage breast carcinomas: prognostic significance. J Surg Oncol 61: 177-184, 1996.
9. Marchetti E, Querzoli P, Moncharmont B, Parikh I, Bagni A, Marzola A, Fabris G, Nenci I: Immunocytochemical demonstration of estrogen receptors by monoclonal antibodies in human breast cancer: Correlation with estrogen receptor assay by dextran-coated charcoal method. Cancer Res 47: 2508-2513, 1987.
10. Pertschuk LP, Kim DS, Nayer K, Feldman JG, Eisenberg KB, Carter AC, Rong ZT, Thelmo WL, Fleisher J, Greene GL: Immunocytochemical estrogen and progestin receptor analysis in breast cancer with monoclonal antibodies. Histopathologic, demographic, and biochemical correlations and relationship to endocrine response and survival. Cancer 66: 1663-1670, 1990.
11. Querzoli P, Ferretti S, Marzola A, Tassinari D, Indelli M, Marchetti E, Fabris G, Nenci I: Clinical usefulness of estrogen receptor immunocytochemistry in human breast cancer. Tumori 78: 287-290, 1992.
12. Reiner A, Neumeister B, Reiner G, Jakesz R, Kolb R, Schemper M, Spona J: Steroidhormonrezeptoren im Mammakarzinom. Immunhistochemischer Nachweis und prognostische Bedeutung. Zentralbl Pathol 137: 233-241, 1991.
13. Stierer M, Rosen H, Weber R, Hanak H, Spona J, Tuchler H: Immunohistochemical and biochemical measurement of estrogen and progesterone receptors in primary breast cancer. Correlation of histopathology and prognostic factors. Ann Surg 218: 13-21, 1993
14. Biesterfeld S, Klüppel D, Koch R, Schneider S, Steinhagen G, Schröder W, Mihalcea AM: Rapid and prognostically valid quantification of immunohistochemical reactions by immunohistometry of the most positive tumor focus. A prospective follow-up study on breast cancer using antibodies against MIB-1, PCNA, ER and PR. J Pathol, accepted for publication, 1997.
15. Sun DQ, Feng CH, Böcking A, Biesterfeld S: Principal component analysis, a factor analytical technique for the determination of interobserver variation in histomorphologic tumor grading. Anticancer Res 14: 1525-1528, 1994.
16. Pinder SE, Ellis IO, Elston CW: Prognostic factors in primary breast cancer. J Clin Pathol 49: 981-983, 1995.
17. Simpson JF, Page DF: Status of breast cancer prognostication based on histopathologic data. Am J Clin Pathol (Suppl) 102: S3-S8, 1994.
18. Joensuu H, Toikkanen S: Identification of subgroups with favorable prognosis in breast cancer. Acta Oncol 31: 293-301, 1992.
19. Nomura Y, Miura S, Koyama H, Enomoto K, Kasumi F, Yamamoto H, Kimura M, Tominaga T, Iino H, Morimoto T, Tashiro H: Relative effect of steroid hormone receptors on the prognosis of patients with operable breast cancer. A univariate and multivariate analysis of 3089 Japanese patients with breast cancer from the Study Group for the Japanese Breast Cancer Society on Hormone Receptors and Prognosis in Breast Cancer.Cancer 69: 153-164, 1992
20. Gasparini G, Pozza F, Dittadi R, Meli S, Cazzavillan S, Bevilacqua P: Progesterone receptor determined by immunocytochemical and biochemical methods in human breast cancer. J Cancer Res Clin Oncol 118: 557-563, 1992
21. Reiner A, Neumeister B, Spona J, Reiner G, Schemper M, Jakesz R: Immunocytochemical localization of estrogen and progesterone receptor and prognosis in human primary breast cancer. Cancer Res 50: 7057-7061, 1990.
22. Stierer M, Rosen H, Weber R, Hanak H, Auerbach L, Spona J, Tuchler H: A prospective analysis of immunohistochemically determined hormone receptors and nuclear features as predictors of early recurrence in primary breast cancer. Breast Cancer Res Treat 36: 11-21, 1995.