Pitfall in HPLC assay for urinary metanephrines: An unusual type of interference caused by methenamine intake

Clinical Chemistry

Volumn 50, Issue 6, 2004, Pages 1097-1099

  Van Laarhoven, Hanneke W M ^a   Willemsen, Jacques J ^a   Alec Ross, H ^a,b   Beex, Louk V A M ^a   Lenders, Jacques W M ^a   Sweep, Fred C G J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Department of Endocrinology ^*  (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

METADRENALIN; METHENAMINE;

ADULT; ANAMNESIS; ARTICLE; CASE REPORT; CLINICAL FEATURE; DISEASE COURSE; DRUG URINE LEVEL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH RISK PATIENT; HUMAN; LABORATORY TEST; LUNG EMBOLISM; MEDICAL EXAMINATION; PHEOCHROMOCYTOMA; PHYSICAL EXAMINATION; RISK ASSESSMENT; THROMBOSIS; URINALYSIS;

ADRENAL GLAND NEOPLASMS; ARM; CATECHOLAMINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIAGNOSIS, DIFFERENTIAL; FALSE POSITIVE REACTIONS; FEMALE; HUMANS; METANEPHRINE; METHENAMINE; MIDDLE AGED; PHEOCHROMOCYTOMA; PULMONARY EMBOLISM; THROMBOEMBOLISM;

EID: 2642586429     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2004.032912     Document Type: Article

References (5)

1. Grumbach MM, Biller BM, Braunstein GD, Campbell KK, Carney JA, Godley PA, et al. Management of the clinically inapparent adrenal mass ("incidentaloma"). Ann Intern Med 2003;138:424-9.
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3. Willemsen JJ, Ross HA, Wolthers BG, Sweep CG, Kema IP. Evaluation of specific high-performance liquid-chromatographic determinations of urinary metanephrine and normetanephrine by comparison with isotope dilution mass spectrometry. Ann Clin Biochem 2001;38(Pt 6):722-30.
4. Lenders JW, Pacak K, Walther MM, Linehan WM, Mannelli M, Friberg P, et al. Biochemical diagnosis of pheochromocytoma: which test is best? JAMA 2002;287:1427-34.
5. Touchstone JC, Stojkewycz M, Smith K. The effect of methenamine mandelate (mandelamine) on determination of urinary estriol. Clin Chem 1965;11:1019-22.