Mutations in a human ROBO gene disrupt hindbrain axon pathway crossing and morphogenesis

Science

Volumn 304, Issue 5676, 2004, Pages 1509-1513

  Jen, Joanna C ^a   Chan, Wai Man ^c   Bosley, Thomas M ^f   Wan, Jijun ^a   Carr, Janai R ^a   Rüb, Udo ^g   Shattuck, David ^a   Salamon, Georges ^b   Kudo, Lili C ^b   Ou, Jing ^a   Lin, Doris D M ^h   Salih, Mustafa A M ⁱ   Kansu, Tülay ^j   Al Dhalaan, Hesham ^k   Al Zayed, Zayed ^k   MacDonald, David B ^k   Stigsby, Bent ^k   Plaitakis, Andreas ^l   Dretakis, Emmanuel K ^l   Gottlob, Irene ^m   Pieh, Christina ⁿ   Traboulsi, Elias I ^o   Wang, Qing ^o   Wang, Lejin ^o,p   Andrews, Caroline ^c,e   Yamada, Koki ^c,e   Demer, Joseph L ^a,b   Karim, Shaheen ^b   Alger, Jeffry R ^b   Geschwind, Daniel H ^a   Deller, Thomas ^g   Sicotte, Nancy L ^a   Nelson, Stanley F ^a   Baloh, Robert W ^a,b   Engle, Elizabeth C ^c,d,e   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Division of Genetics   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f KING KHALED EYE SPECIALIST HOSPITAL   (Saudi Arabia)

^g GOETHE UNIVERSITY   (Germany)

^h JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ KING KHALID UNIVERSITY HOSPITAL   (Saudi Arabia)

^j HACETTEPE UNIVERSITY   (Turkey)

^k KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^l UNIVERSITY OF CRETE   (Greece)

^m UNIVERSITY OF LEICESTER   (United Kingdom)

ⁿ UNIVERSITY OF FREIBURG   (Germany)

^o LERNER RESEARCH INSTITUTE   (United States)

^p PEKING UNIVERSITY   (China)

more..

Author keywords

[No Author keywords available]

Indexed keywords

HINBRAIN; HUMAN ROBO GENES; MUTATIONS; SOMATOSENSORY AXONS;

BIOLOGICAL ORGANS; BRAIN; MUTAGENESIS; NEUROLOGY; PATIENT MONITORING; PROTEINS;

GENES;

MEMBRANE RECEPTOR; MESSENGER RNA; ROUNDABOUT RECEPTOR;

GENE;

ARTICLE; BRAIN DEVELOPMENT; DISABILITY; EYE MOVEMENT; GAZE PARALYSIS; GENE; GENE MUTATION; HORIZONTAL GAZE PALSY WITH PROGRESSIVE SCOLIOSIS; HUMAN; LUMBAR SPINE; MORPHOGENESIS; MOTOR CONTROL; NERVE FIBER; NERVOUS SYSTEM DEVELOPMENT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RHOMBENCEPHALON; ROBO GENE; ROBO3 GENE; ROUNDABOUT GENE; SCOLIOSIS; SYNDROME DELINEATION;

ADULT; ALTERNATIVE SPLICING; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AXONS; EVOKED POTENTIALS, MOTOR; EVOKED POTENTIALS, SOMATOSENSORY; FEMALE; FUNCTIONAL LATERALITY; HUMANS; IN SITU HYBRIDIZATION; LINKAGE (GENETICS); MAGNETIC RESONANCE IMAGING; MALE; MEDULLA OBLONGATA; MICROSATELLITE REPEATS; MOLECULAR SEQUENCE DATA; MORPHOGENESIS; MUTATION; NEURAL PATHWAYS; OPHTHALMOPLEGIA; PEDIGREE; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, IMMUNOLOGIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHOMBENCEPHALON; SCOLIOSIS; SEQUENCE ANALYSIS, DNA; SYNDROME;

DANIO RERIO; MURINAE;

EID: 2642584008     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1096437     Document Type: Article

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