Evaluation of simplified kinetic analyses for measurement of brain acetylcholinesterase activity using N-[11C]methylpiperidin-4-yl propionate and positron emission tomography

Journal of Cerebral Blood Flow and Metabolism

Volumn 24, Issue 6, 2004, Pages 600-611

  Sato, Koichi ^a   Fukushi, Kiyoshi ^a   Shinotoh, Hitoshi ^a,b   Nagatsuka, Shin Ichiro ^a,c   Tanaka, Noriko ^a,d   Aotsuka, Akiyo ^a   Ota, Tsuneyoshi ^a,e   Shiraishi, Tetsuya ^a   Tanada, Shuji ^a   Iyo, Masaomi ^a   Irie, Toshiaki ^a,f  

^a CHIBA UNIVERSITY   (Japan)

^b Asahi Neurological Hospital   (Japan)

^c DAIICHI PURE CHEMICALS CO LTD   (Japan)

^d TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^e JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

Acetylcholinesterase; Brain; Cholinergic; Kinetic analysis; N 11C methyl piperidin 4 yl propionate (MP4P); Positron emission tomography (PET)

Indexed keywords

ACETYLCHOLINESTERASE; BRAIN ENZYME; CARBON 11; N METHYLPIPERIDIN 4 YL PROPIONATE C 11; PROPIONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BRAIN REGION; CEREBELLUM; COMPARTMENT MODEL; COMPUTER SIMULATION; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVITY; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN EXPERIMENT; MALE; NEOCORTEX; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; REACTION TIME; REGRESSION ANALYSIS; THALAMUS;

EID: 2642550047     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.WCB.0000117689.98763.6A     Document Type: Article

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