Characterization of mixed lymphocyte reaction blocking antibodies (MLR-Bf) in human pregnancy

BMC Pregnancy and Childbirth

Volumn 3, Issue , 2003, Pages

  Kumar Pandey, Manoj ^a   Saxena, Vijay ^a   Agrawal, Suraksha ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BLOCKING ANTIBODY; CYTOTOXIC ANTIBODY; IMMUNOGLOBULIN G; LYMPHOCYTE ANTIBODY; PHYTOHEMAGGLUTININ;

ADOLESCENT; ADULT; ANTIBODY DETECTION; ANTIBODY RESPONSE; ANTIGEN ANTIBODY REACTION; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; FEMALE; FIRST TRIMESTER PREGNANCY; GESTATION PERIOD; HUMAN; HUMAN EXPERIMENT; IMMUNOREACTIVITY; IMMUNOTHERAPY; LYMPHOCYTE PROLIFERATION; MALE; MIXED LYMPHOCYTE REACTION; PREGNANCY; SECOND TRIMESTER PREGNANCY; SPONTANEOUS ABORTION; SPOUSE; THIRD TRIMESTER PREGNANCY;

EID: 2642531983     PISSN: 14712393     EISSN: 14712393     Source Type: Journal    
DOI: 10.1186/1471-2393-3-2     Document Type: Article

References (22)

1. Stephenson MD Frequency of factors associated with habitual abortion in 197 couples. Fertil Steril 1996, 66:24-29
2. Hassold T, Abruzzo M, Adkins K, Griffin D, Merrill M, Millie E, Saker D, Shen J and Zaragoza M Human aneuploidy: incidence, origin and etiology. Environ Mol Mutagen 1996, 28:167-175
3. Beer AE Immunopathologic factors contributing to recurrent spontaneous abortions in humans. Am J Reprod Immunol 1983, 4:182-184
4. Rodger JC Lack of a requirement for a maternal humoral immune response to establish or maintain successful allogeneic pregnancy. Transplantation 1985, 40(4):372-377
5. Chaouat G, Voisin GA, Escalier D and Robert P Facilitation reaction (enhancing antibodies and suppressor cells) and rejection reaction (sensitized cells) from the mother to the paternal antigens of the conceptus. Clin Exp Immunol 1979, 35(1):13-24
6. Gentile T, Borel IM, Angelucci J, Miranda S and Margni RA Preferential synthesis of asymmetric antibodies in rats immunized with paternal particulate antigens. Effect on pregnancy. J Reprod Immunol 1992, 22:173-183
7. Kelemen K, Bognar I, Paal M and Szekeres-Bartho J A progesterone-induced protein increases the synthesis of asymmetric antibodies. Cell Immunol 1996, 167:129-34
8. Agrawal S, Pandey MK, Mandal SK, Mishra LC and Agarwal SS Humoral immune response to an allogenic foetus in normal fertile women and recurrent aborters. BMC Pregnancy and Childbirth 2002, 2:6
9. Eblen AC, Gercel-Taylor C, Shields LB, Sanfilippo JS, Nakajima ST and Taylor DD Alterations in humoral immune responses associated with recurrent pregnancy loss. Fertil Steril 2000, 73(2):305-313
10. Zenclussen AC, Gentile T, Kortebani G, Mazzolli A and Margni R Asymmetric antibodies and pregnancy. Am J Reprod Immunol 2001, 45(5):289-294
11. Tamura M, Takakuwa K, Arakawa M, Yasuda M, Kazama Y and Tanaka K Relationship between MLR blocking antibodies and the outcome of the third pregnancy in patients with two consecutive spontaneous abortions. J Perinat Med 1998, 26(1):49-53
12. Ramhorst R, Agriello E, Zittermann S, Pando M, Larriba J, Irigoyen M, Cortelezzi M, Auge L, Lombardi E, Etchepareborda JJ, Contreras Ortiz C and Fainboim L Is the paternal mononuclear cells' immunization a successful treatment for recurrent spontaneous abortion? Am J Reprod Immunol 2000, 44(3):129-135
13. Agrawal S, Pandey MK and Pandey A Prevalence of MLR blocking antibodies before and after immunotherapy. J Hematother Stem Cell Res 2000, 9(2):257-262
14. Pope RM Immuno-regulatory mechanisms present in the maternal circulation during pregnancy. Bailliere's Clin Rheumatol 1990, 4:33-51
15. Hill JA, Polgar K and Anderson D T-helper 1-type immunity to trophoblast in women with recurrent spontaneous abortion. JAMA 1995, 273(24):1933-1936
16. Vlaanderen W and Treffers PE Prognosis of subsequent pregnancies after recurrent spontaneous abortion in first trimester. Br Med J Clin Res Ed 1987, 295:92-93
17. Szekeres-Bartho J and Wegmann TG progesterone - dependent immunomodulatory protein alters the Th1/Th2 balance. J Reprod Immunol 1996, 31(1-2):81-95
18. Gatenby PA, Moore H, Cameron K, Doran TJ and Adelstein S Treatment of recurrent spontaneous abortion by immunization with paternal lymphocytes: correlates with outcome. Am J Reprod Immunol 1989, 19(1):21-27
19. Wegmann TG, Mosmann TR, Carlson GA, Olijnyk O and Singh B The ability of the murine placenta to absorb monoclonal anti-fetal H-2K antibody from the maternal circulation. J Immunol 1979, 123(3):1020-1023
20. Beer AE, Semprini AE, Zhu XY and Quebbeman JF Pregnancy outcome in human couples with recurrent spontaneous abortions: HLA antigen profiles; HLA antigen sharing; female serum MLR blocking factors and paternal leukocyte immunization. Exp Clin Immunogenet 1985, 2(3):137-153
21. Creus M, Balasch J, Fabregues F, Martorell J, Boada M, Penarrubia J, Barri PN and Vanrell JA Parental human leukocyte antigens and implantation failure after in-vitro fertilization. Hum Reprod 1998, 13(1):39-43
22. Stach RM and Rowley DA A first or dominant immunization II induced immunoglobulin carries transforming growth factor β and suppresses cytolytic T cell response to unrelated alloantigens. J Exp Med 1993, 178:835