Can statins treat the strokes they fail to prevent?

Journal of the Neurological Sciences

Volumn 221, Issue 1-2, 2004, Pages 1-2

  Jacobs, Bradley S ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYPOCHOLESTEROLEMIC AGENT; LIVER ENZYME; LOW DENSITY LIPOPROTEIN; STATIN;

CARDIOVASCULAR RISK; CORONARY ARTERY DISEASE; DIABETES MELLITUS; EDITORIAL; HUMAN; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROKE; THROMBOCYTE AGGREGATION; TREATMENT OUTCOME; UPREGULATION;

ANIMALS; ANTICHOLESTEREMIC AGENTS; CEREBROVASCULAR ACCIDENT; CLINICAL TRIALS; DISEASE MODELS, ANIMAL; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS;

EID: 2642521890     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2004.03.004     Document Type: Editorial

References (6)

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2. Zacco A., Togo J., Spence K., Ellis A., Lloyd D., Furlong S., et al. 3-Hydroxy-3-methylglutaryl coenzyme a reductase inhibitors protect cortical neurons from excitotoxicity. J. Neurosci. 23(35):2003;11104-11111
3. Takemoto M., Liao J.K. Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler. Thromb. Vasc. Biol. 21(11):2001;1712-1719
4. Vaughan C.J. Prevention of stroke and dementia with statins: effects beyond lipid lowering. Am. J. Cardiol. 91(4A):2003;23B-29B
5. Libby P. Current concepts of the pathogenesis of the acute coronary syndromes. Circulation. 104(3):2001;365-372
6. Greisenegger S., Mullner M., Tentschert S., Lang W., Lalouschek W. Effect of pretreatment with statins on the severity of acute ischemic cerebrovascular events. J. Neurol. Sci. 221:2004;5-10 [this issue]