Silencing of imprinted CDKN1C gene expression is associated with loss of CpG and histone H3 lysine 9 methylation at DMR-LIT1 in esophageal cancer

Oncogene

Volumn 23, Issue 25, 2004, Pages 4380-4388

  Soejima, Hidenobu ^a   Nakagawachi, Tetsuji ^a   Zhao, Wei ^a   Higashimoto, Ken ^a   Urano, Takeshi ^b   Matsukura, Shiroh ^a   Kitajima, Yoshihiko ^a   Takeuchi, Makoto ^c   Nakayama, Masahiro ^c   Oshimura, Mitsuo ^d   Miyazaki, Kohji ^a   Joh, Keiichiro ^a   Mukai, Tsunehiro ^a  

^a SAGA UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c RESEARCH INSTITUTE FOR MATERNAL AND CHILD HEALTH   (Japan)

^d TOTTORI UNIVERSITY   (Japan)

Author keywords

CDKN1C; CpG methylation; Differentially methylated region; Histone H3 lysine 9 methylation; Imprinting control region

Indexed keywords

HISTONE H3; LYSINE; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN CDKN1C; UNCLASSIFIED DRUG; CDKN1C PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1C; HISTONE; LIT1 RNA; NUCLEAR PROTEIN; TUMOR PROTEIN; UNTRANSLATED RNA;

ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CPG ISLAND; ESOPHAGUS CANCER; GENE EXPRESSION; GENE LOSS; GENE SILENCING; HUMAN; HUMAN CELL; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN MODIFICATION; STATISTICAL SIGNIFICANCE; BIOSYNTHESIS; CHROMOSOME 11; DNA METHYLATION; ESOPHAGUS TUMOR; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; GENOME IMPRINTING; METABOLISM; PATHOLOGY; PROTEIN PROCESSING; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

CELL LINE, TUMOR; CHROMOSOMES, HUMAN, PAIR 11; CPG ISLANDS; CYCLIN-DEPENDENT KINASE INHIBITOR P57; DNA METHYLATION; EPIGENESIS, GENETIC; ESOPHAGEAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, TUMOR SUPPRESSOR; GENOMIC IMPRINTING; HISTONES; HUMANS; METHYLATION; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, UNTRANSLATED;

EID: 2642519400     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207576     Document Type: Article

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