Selected Applications of Reduced Uncertainty Factors in Noncancer Risk Assessment

Human and Ecological Risk Assessment: An International Journal

Volumn 1, Issue 5, 1995, Pages 637-640

  Poirier, Kenneth A ^b  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

extrapolation; regulatory toxicology; risk assessment; uncertainty factors

Indexed keywords

EID: 26244461925     PISSN: 10807039     EISSN: 15497860     Source Type: Journal    
DOI: 10.1080/10807039509380053     Document Type: Article

References (10)

1. Barnes, D.G., and Dourson, M.L. 1988. Reference Dose (RfD): Description and use in health risk assessments. Regul. Toxicol. Pharmacol. 8, 471–486.
2. Barsotti, D.A., and Van Miller, J.P. 1984. Accumulation of a commercial polychlorinated biphenyl mixture (Aroclor 1016) in adult rhesus monkeys and their nursing infants. Toxicology 30, 31–44.
3. Gaul L.E., and Staud, A.H. 1935. Clinical spectroscopy. Seventy cases of generalized argyrosis following organic and colloidal silver medication including a biospectrometric analysis of ten cases.J. Am. Med. Assoc. 104, 1387-1390.
4. Koval’skiy, V.V., Yarovaya, G.A., and Shmavonyan, D.M. 1961. Changes of purine metabolism in man and animals under conditions of molybdenum biochemical provinces. Zh. Obshch. Biol. 22, 179-191.
5. Lehman A.J., and Fitzhugh, O.G. 1954. 100-Fold margin of safety. Assoc. Food Drug Off. U.S. Q. Bull. 18, 33–35.
6. Marsh, D.O., Clarkson, T.W., and Cox, C. 1987. Fetal methylmercury poisoning: Relationship between concentration in a single strand of maternal hair and child effects. Arch. Neurol. 44, 1017-1022.
7. Storey, E. 1961. Strontium “rickets,” bone calcium and strontium changes. Austral. Ann. Med. 10, 213-222.
8. USEPA (U.S. Environmental Protection Agency). 1995. Integrated Risk Information System (IRIS). Online. Office of Health and Environmental Assessment, Environmental Criteria Assessment Office, Cincinnati, OH 45268.
9. Yadrick, M.K., Kenny, M.A., and Winterfeldt, E.A. 1989. Iron, copper, and zinc status: Response to supplementation with zincew or zinc and iron in adult females. Am.J. Clin. Nutr. 49, 145-150
10. Yang, G., Zhou, R., and Yin, S. 1989. Studies of safe maximal daily dietary selenium intake in a seleniferous area in China. I. Selenium intake and tissue selenium levels of the inhabitants. J. Trace Elements Electrol. Health Dis. 3, 77–87.