Bronchial hyper-responsiveness predicts the development of mild clinical asthma within 2 yr in school children with hay-fever

Pediatric Allergy and Immunology

Volumn 16, Issue 6, 2005, Pages 478-486

  Ferdousi, Hosne Ara ^a   Zetterström, Olle ^a   Dreborg, Sten ^a,b  

^a LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

^b NONE   (Sweden)

Author keywords

Asthma; Bronchial hyperresponsiveness; Eosinophil cationic protein; Eosinophil protein X; Hay fever; Iso capnic hyperventilation of cold air provocation test; Methacholine bronchial provocation test; Peak expiratory flow rate

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CROMOGLYCATE DISODIUM; METHACHOLINE; STEROID;

ALLERGIC DISEASE; ARTICLE; ASTHMA; BLOOD LEVEL; BRONCHUS HYPERREACTIVITY; CLINICAL ARTICLE; COLD AIR; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; FEMALE; FOLLOW UP; HAY FEVER; HUMAN; HYPERVENTILATION; MALE; MEDIATOR; PEAK EXPIRATORY FLOW; POLLEN ALLERGY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROVOCATION TEST; SELF EVALUATION; SYMPTOM; URINE LEVEL; VALIDATION PROCESS; VISUAL ANALOG SCALE;

ADOLESCENT; ANTI-ASTHMATIC AGENTS; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHIAL PROVOCATION TESTS; CHILD; FEMALE; FOLLOW-UP STUDIES; FORCED EXPIRATORY VOLUME; HUMANS; INFLAMMATION MEDIATORS; MALE; PAIN MEASUREMENT; PEAK EXPIRATORY FLOW RATE; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RHINITIS, ALLERGIC, SEASONAL; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX;

EID: 26244437471     PISSN: 09056157     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3038.2005.00296.x     Document Type: Article

References (31)

1. BRITTON J, LEWIS S. Objective measures and the diagnosis of asthma. We need a simple diagnostic test-but don't yet have one. BMJ 1998: 317: 227-8.
2. FERDOUSI HA, DREBORG S. Asthma, bronchial hyperreactivity and mediator release in children with birch pollinosis. Clin Exp Allergy, 1997: 27: 530-9.
3. WOOLCOCK AJ. What is bronchial hyperresponsiveness from the clinical standpoint?. In: PAGE CP, GARDINER PJ, eds. In Airway Hyperresponsiveness: Is it Really Important for Asthma? Chap 1. Oxford, UK: Blackwell Scientific Publications, 1993.
4. JANSEN DF, TIMMENS W, KRAAN J, RIJCKEN B, POSTMA DS. (A)symptomatic bronchial hyper-responsiveness and asthma. Respir Med 1997: 91: 121-34.
5. PAUWELS R, JOOS G, VAN DER STRATEN M. Bronchial responsiveness is not asthma. Clin Allergy 1988: 18: 317-21.
6. ZACH MS, POLGAR G. Cold air challenge of airway hyperreactivity in children: dose-response interrelation with a reaction plateau. J Allergy Clin Immunol 1987: 80: 9-17.
7. MENKES HA. Airway reactivity and the need for a simple test. Am Rev Respir Dis 1980: 121: 619-20.
8. LARSSON K, TORNLING G, GAVHED D, MULLER-SUUR C, PALMBERG L. Inhalation of cold air increases the number of inflammatory cells in the lungs in healthy subjects. Eur Respir J 1998: 12: 825-30.
9. MÖLLER C, DREBORG S, FERDOUSI HA, et al. Pollen immunotherapy reduces the development of asthma in children with seasonal rhino-conjunctivitis (The PAT-Study). J Allergy Clin Immunol 2002: 109: 251-6.
10. PIPKORN U. Pharmacological influence of anti-allergic medication on in vivo allergen testing. Allergy 1988: 43: 81-6.
11. FREDRIKSSON HV, MALMBERG P, HEDENSTRÖM H, HILLERDAL G. Reference value for respiratory function tests in males: prediction formulas with tobacco smoking parameters. Clin Physiol 1981: 1: 349-64.
12. HEDENSTRÖM H, MALMBERG P, AGARWAL K. Reference values for lung function tests in females. Regression equation with smoking variables. Bull Eur Physiopathol Respir 1985: 21: 551-7.
13. HURWITZ KM, ARGYROS GJ, ROACH JM, ELIASSON AH, PHILLIPS YY. Interpretation of eucapnic voluntary hyperventilation in the diagnosis of asthma. Chest 1995: 108: 1240-5.
14. MATTHYS H, KNOCK M, ELTSCHKA R. A new aerosol device for bronchial provocation tests. Respiration 1993: 60: 343-50.
15. SOLYMER L, ARONSSON P-H, BAKE B, BJURE J. Nitrogen single breath test, flow-volume curves and spirometry in healthy children 7-18 years of age. Eur J Respir Dis 1980: 61: 275-86.
16. FERDOUSI HA, MUNIR AKM, ZETTERSTRÖM O, DREBORG S. Seasonal variation of peak expiratory flow rate variability and mediators of allergic inflammation in non atopic school children. Pediatr Allergy Immunol 2001: 12: 238-46
17. PETERSON CGB, ENANDER I, NYSTRAND J, ANDERSSON AS, NILSSON L, VENGE P. Radioimmunoassay of human eosinophil cationic protein (ECP) by an improved method. Establishment of normal levels in serum and turn over in vivo. Clin Exp Allergy 1991: 21: 561-7.
18. OLOFSSON T, OLSSON I, VENGE P, ELGEFORS B. Serum myelo-peroxidase and lactoferrin in neutropenia. Scand J Haematol 1977: 18: 73-80.
19. GALEN RS, GAMBINO SR. Beyond Normality. The Predictive Value and Efficiency of Medical Diagnose. New York: John Wiley & Sons, 1975.
20. DAVID DL, SAMSA GP, MATCHAR B. Likelihood ratios with confidence: sample size estimation for diagnostic test studies. J Clin Epidemiol 1991: 44: 763-70.
21. ZHONG NS, CHEN RC, YANG MO, WU ZY, ZHENG JP, LI YF. Is asymptomatic bronchial hyperresponsiveness an indication of potential asthma? A two-year follow-up of young students with bronchial hyperresponsiveness. Chest 1992: 102: 1104-9.
22. BOUSQUET J, VAN CAUWENBERGE P, KHALTAEV N. Allergic rhinitis and its impact on asthma. ARIA Workshop Report. J Allergy Clin Immunol 2001: 108: S147-S333.
23. BRAUNSTAHL GJ, KLEINJAN A, OVERBEEK SE, PRINS JB, HOOGSTEDEN HC, FOKKENS WJ. Segmental bronchial provocation induces nasal inflammation in allergic rhinitis patients. Am J Respir Crit Care Med 2000: 161: 2051-7.
24. BRAUNSTAHL GJ, OVERBEEK SE, KLEINJAN A, PRINS JB, HOOGSTEDEN HC, FOKKENS WJ. Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways. J Allergy Clin Immunol 2001: 107: 469-76.
25. TOWNLEY RG, RYO UY, KOLOTKIN BM, KANG B. Bronchial sensitivity to methacholine in current and former asthmatic and allergic rhinitis patients and control subjects. J Allergy Clin Immunol 1975: 56: 429-42.
26. RACKEMANN FM, EDWARDS MC. A follow-up study of 688 patients after an interval of twenty years. N Engl J Med 1952: 246: 815-23.
27. LINNA O, KOKKONEN J, LUKIN M. A 10-year prognosis for childhood allergic rhinitis. Acta Paediatr 1992: 81: 100-2.
28. DE BENEDICTIS FM, CANNY GJ, MACLUSKY IB, LEVISON H. Comparison of airway reactivity induced by cold air and methacholine challenges in asthmatic children. Pediatr Pulmonol 1995: 19: 326-9.
29. NAIR N, HOPP RJ, ALPER BI, BEWTRA AK, TOWNLEY RG. Correlations of methacholine induced non-specific bronchial reactivity and cold air hyperventilation challenge. Ann Allergy 1986: 56: 226-8.
30. AGERTOFT L, PEDERSEN S. Effects of long-term treatment with an inhaled corticosteroid on growth and pulmonary function in asthmatic children. Respir Med 1994: 88: 373-81.
31. FILUK RB, SERRETTE C, ANTHONISEN NR. Comparison of Responses to Methacholine and Cold Air in Patients Suspected of Having Asthma. Chest 1989: 95: 948-52.