Treatment of giant cell tumors with allograft transplants: A 30-year study

Clinical Orthopaedics and Related Research

Volumn 439, Issue , 2005, Pages 144-150

  Mankin, Henry J ^a   Hornicek, Francis J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLY(METHYL METHACRYLATE);

ADOLESCENT; ADULT; ALLOTRANSPLANTATION; ARTICLE; BONE DESTRUCTION; BONE RADIOGRAPHY; CADAVER; CANCER GRADING; CANCER GRAFT; CONSERVATIVE TREATMENT; FEMALE; GIANT CELL TUMOR; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; IMPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PSEUDARTHROSIS; RETROSPECTIVE STUDY; BONE TRANSPLANTATION; BONE TUMOR; MIDDLE AGED; OSTEOCLASTOMA; PATHOLOGY; POSTOPERATIVE COMPLICATION; RADIOGRAPHY; TREATMENT OUTCOME; TUMOR RECURRENCE;

ADOLESCENT; ADULT; BONE NEOPLASMS; BONE TRANSPLANTATION; FEMALE; GIANT CELL TUMOR OF BONE; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; POSTOPERATIVE COMPLICATIONS; RETROSPECTIVE STUDIES; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME;

EID: 26244437309     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1097/01.blo.0000174684.85250.b5     Document Type: Article

References (56)

1. Aho AJ, Eskola J, Ekfors T, et al: Immune responses and clinical outcome of massive human osteoarticular allografts. Clin Orthop 346:196-206, 1998.
2. Berrey Jr BH, Lord CF, Gebhardt MC, Mankin HJ: Fractures of allograft fractures: Frequency, treatment and end-results. J Bone Joint Surg 72A:822-833, 1990.
3. Campanacci M: Giant cell tumor of bone. In Campanacci M (ed). Bone and Soft Tissue Tumors. Ed 2. Berlin, Springer Verlag 99-132, 1999.
4. Campanacci M, Baldini N, Boriani S, Sudanese A: Giant-cell tumor of bone. J Bone Joint Surg 69A:106-114, 1987.
5. Campanacci M, Giunti A, Olmi R: Giant cell tumours of bone: A study of 209 cases with long term followup in 130. Ital J Orthop Traumatol 1:249-277, 1975.
6. Capanna R, Fabbri N, Bettelli G: Curettage of giant cell tumor of bone: The effect of surgical technique and adjuvants on local recurrence rate. Chir Organi Mov 75(Suppl):206, 1990.
7. Capanna R, Sudanese A, Baldini N, Campanacci M: Phenol as an adjuvant in the control of local recurrence of benign neoplasms of bone treated by curettage. Ital J Orthop Traumatol 11:381-388, 1985.
8. Cox DR: Regression models and life tables. J R Stat Soc 34:187-220, 1972.
9. Dahlin DC, Cupps R, Johnson Jr EW: Giant cell tumor: A study of 195 cases. Cancer 25:1061-1070, 1970.
10. deCamargo EP, deCamargo OP: Surgical treatment of benign cavitary bone lesions using methyl methacrylate cement and polyethylene prosthesis: Experience with 135 cases. In Enneking WF (ed). Limb Salvage in Musculoskeletal Oncology. New York, Churchill Livingstone 519-527, 1987.
11. Delloye C, de Nayer P, Allington N, et al: Massive bone allografts in large skeletal defects after tumor surgery: A clinical and microradiographic evaluation. Arch Orthop Trauma Surg 107:31-41, 1988.
12. Dick HM, Malinin TI, Mnaymneh WA: Massive allograft implantation following radical section of high-grade tumors requiring adjuvant chemotherapy treatment. Clin Orthop 197:88-95, 1985.
13. Donati D, Giacomini S, Gozzi E, et al: Allograft arthrodesis treatment of bone tumors: A two-center study. Clin Orthop 400:217-224, 2002.
14. Enneking WF: A system for evaluation of the surgical management of musculoskeletal tumors. In Enneking WF (ed). Limb Salvage in Musculoskeletal Oncology. New York, Churchill Livingstone 145-150, 1987.
15. Enneking WF, Spanier SS, Goodman MA: Current concepts review: The surgical staging of musculoskeletal sarcoma. J Bone Joint Surg 62A:1027-1030, 1980.
16. Friedlaender GE: Immune responses to osteochondral allografts: Current knowledge and future directions. Clin Orthop 174:58-68, 1983.
17. Friedlaender GE: Bone allografts: The biological consequences of immunological events. J Bone Joint Surg 73A:1119-1122, 1991.
18. Gitelis S, Mallin BA, Piasecki P, Turner F: Intralesional excision compared with en bloc resection for giant-cell tumors. J Bone Joint Surg 75A:1648-1655, 1993.
19. Goldenberg RR, Campbell CJ, Bonfiglio M: Giant-cell tumor of bone: An analysis of two hundred and eighteen cases. J Bone Joint Surg 52A:619-664, 1970.
20. Goldring SR, Schiller AL, Mankin HJ, et al: Characterization of cells from human giant cell tumors of bone. Clin Orthop 204:59-75, 1986.
21. Harness NG, Mankin HJ: Giant-cell tumor of the distal forearm. J Hand Surg 29A:188-193, 2004.
22. Hazan EJ, Hornicek FJ, Tomford W, et al: The effect of adjuvant chemotherapy on osteoarticular allografts. Clin Orthop 385:176-181, 2001.
23. Hornicek FJ, Gebhardt MC, Sorger JI, Mankin HI: Tumor reconstructions. Orthop Clin North Am 30:673-684, 1999.
24. Hornicek FJ, Gebhardt MC, Tomford WW, et al: Factors affecting nonunion of the allograft-host junction. Clin Orthop 382:87-98, 2001.
25. Hornicek FJ, Mnaymneh W, Lackman RD, et al: Limb salvage with osteoarticular allografts after resection of the proximal tibia bone tumors. Clin Orthop 352:179-186, 1998.
26. Hutter RV, Worcester Jr JN, Francis KC, et al: Benign and malignant giant cell tumors of bone: A clinicopathological analysis of the natural history of the disease. Cancer 15:653-690, 1962.
27. Jaffe HL, Lichtenstein L, Portis RB: Giant cell tumor of bone: Its pathologic appearance, grading, supposed variants and treatment. Arch Pathol 30:993-1031, 1940.
28. Johnston J: Treatment of giant cell bone tumors by aggressive curettage and packing with bone cement. In Enneking WF (ed). Limb Salvage in Musculoskeletal Oncology. New York, Churchill Livingstone 512-516, 1987.
29. Kocher MS, Gebhardt MC, Mankin HJ: Reconstruction of the distal aspect of the radius with use of an osteoarticular allograft after excision of a skeletal tumor. J Bone Joint Surg 80A:407-419, 1998.
30. Lausten GS, Jensen PK, Schiodt T, Lund B: Local recurrences in giant cell tumour of bone: Long-term followup of 31 cases. Int Orthop 20:172-176, 1996.
31. Lord CF, Gebhardt MC, Tomford WW, Mankin HJ: The incidence, nature, and treatment of allograft infections. J Bone Joint Surg 70A:369-376, 1988.
32. Mankin HJ: Complications of allograft surgery. In Friedlaender GE, Mankin HJ, Sell KW (eds). Osteochondral Allografts. Boston, Little, Brown and Company 259-274, 1983.
33. Mankin HJ: A computerized system for orthopaedic oncology. Clin Orthop 398:252-261, 2002.
34. Mankin HJ, Doppelt SH, Sullivan TR, Tomford WW: Osteoarticular and intercalary allograft transplantation in the management of malignant tumors of bone. Cancer 50:613-630, 1982.
35. Mankin HJ, Gebhardt MC, Jennings LC, et al: Long-term results of allograft replacement in the management of bone tumors. Clin Orthop 324:86-97, 1996.
36. Mnaymneh WA, Dudley HR, Mnaymneh LG: Giant-cell tumor of bone: An analysis and follow-up study of the forty-one cases observed at the Massachusetts General Hospital between 1925 and 1960. J Bone Joint Surg 45A:63-75, 1964.
37. Mnaymneh W, Malinin TI, Makley JT, Dick HM: Massive osteoarticular allografts in the reconstruction of extremities following resection of tumors not requiring chemotherapy and radiation. Clin Orthop 197:76-87, 1985.
38. O'Donnell RJ, Springfield DS, Motwani HK, et al: Recurrence of giant cell tumors of the long bones after curettage and packing with cement. J Bone Joint Surg 76A:1827-1833, 1994.
39. Ortiz-Cruz E, Gebhardt MC, Jennings LC, et al: The result of transplantation of intercalary allografts after resection of tumors: A long term follow-up study. J Bone Joint Surg 79A:97-106, 1997.
40. Ottolenghi CE: Massive osteoarticular bone grafts. J Bone Joint Surg 48B:646-659, 1966.
41. Pals SD, Wilkins RM: Giant cell tumor of bone treated by curettage, cementation, and bone grafting. Orthopedics 15:703-708, 1992.
42. Parrish FF: Treatment of bone tumors by total excision and replacement with massive autologous and homologous grafts. J Bone Joint Surg 48A:968-990, 1966.
43. Parrish FF: Allograft replacement of part of the end of a long bone following excision of a tumor. J Bone Joint Surg 55A:1-22, 1973.
44. Peimer CA, Schiller AI, Mankin HJ, Smith RJ: Multicentric giant-cell tumor of bone. J Bone Joint Surg 62A:652-656, 1980.
45. Persson BM, Ekelund L, Lovdahl R, Gunterberg B: Favorable results of acrylic cementation for giant cell bone tumors. Acta Orthop Scand 55:209-214, 1984.
46. Rock MG, Pritchard DJ, Unni KK: Metastases from histologically benign giant cell tumor of bone. J Bone Joint Surg 66A:269-274, 1984.
47. Sanerkin NG: Malignancy, aggressiveness, and recurrence in giant cell tumor of bone. Cancer 46:1641-1649, 1980.
48. Schajowicz F: Giant-cell tumors of bone (osteoclastoma): A pathological and histochemical study. J Bone Joint Surg 43A:1-29, 1961.
49. Scully SP, Mott MP, Temple HT, et al: Late recurrence of giant-cell tumor of bone: A report of four cases. J Bone Joint Surg 76A:231-1233, 1994.
50. Sim, FH, Dahlin DC, Beabout JW: Multicentric giant-cell tumor of bone. J Bone Joint Surg 59A:1052-1060, 1977.
51. Smith RJ, Mankin HJ: Allograft replacement of distal radius for giant cell tumor. J Hand Surg 2A:299-309, 1977.
52. Sorger JI, Hornicek FJ, Zavatta M, et al: Allograft fractures revisited. Clin Orthop 382:66-74, 2001.
53. Stevenson S, Emery SE, Goldberg VM: Factors affecting bone graft incorporation. Clin Orthop 324:66-74, 1996.
54. Tan MH, Mankin HJ: Blood transfusion and bone allografts: Effect on infection and outcome. Clin Orthop 340:207-214, 1997.
55. Tomford WW: Cryopreservation of articular cartilage. In Friedlaender GE, Mankin HJ, Sell KW (eds). Osteochondral Allografts. Boston, Little, Brown and Company 215-218, 1983.
56. Tomford WW, Thongphasuk J, Mankin HJ, Ferraro MJ: Frozen musculoskeletal allografts: A study of the clinical incidence and causes of infection associated with their use. J Bone Joint Surg 72A:1137-1143, 1990.