A dual inhibitor of TNF-α and IL-1 mitigates liver and kidney dysfunction and improves survival in rat endotoxemia

Hepato-Gastroenterology

Volumn 52, Issue 65, 2005, Pages 1507-1510

  Takeyoshi, Izumi ^a   Yoshinari, Daisuke ^a   Kobayashi, Mitsunobu ^a   Kurabayashi, Makoto ^a   Morishita, Yasuo ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

FR167653; IL 1; Kidney dysfunction; Lipopolysaccharide; Liver dysfunction; Rat; TNF

Indexed keywords

1 [7 (4 FLUOROPHENYL) 1,2,3,4 TETRAHYDRO 8 (4 PYRIDYL)PYRAZOLO[5,1 C][1,2,4]TRIAZIN 2 YL] 2 PHENYLETHANEDIONE; ASPARTATE AMINOTRANSFERASE; CREATININE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 1; TUMOR NECROSIS FACTOR ALPHA; UREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD SAMPLING; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG INHIBITION; DRUG MECHANISM; ENDOTOXEMIA; KIDNEY DYSFUNCTION; LIVER DYSFUNCTION; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEPTIC SHOCK; SURVIVAL RATE; UREA NITROGEN BLOOD LEVEL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ENDOTOXEMIA; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; LIVER DISEASES; LIVER FUNCTION TESTS; LUNG DISEASES; MALE; PYRAZOLES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 25844526548     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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