Patient-control association study of substance P-related genes in unipolar and bipolar affective disorders

International Journal of Neuropsychopharmacology

Volumn 8, Issue 4, 2005, Pages 505-513

  Mendlewicz, Julien ^a   Oswald, Pierre ^a   Claes, Stephan ^b   Massat, Isabelle ^a   Souery, Daniel ^a   Van Broeckhoven, Christine ^b   Del Favero, Jurgen ^b  

^a ERASME HOSPITAL   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

Association; Bipolar affective disorder; Substance P; Unipolar affective disorder

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; SUBSTANCE P;

ADULT; AFFECTIVE PSYCHOSIS; ARTICLE; BIPOLAR DISORDER; CONTROLLED STUDY; FEMALE; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC IDENTIFICATION; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE PHENOTYPE CORRELATION; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SAMPLE SIZE; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; ALLELES; BELGIUM; BIPOLAR DISORDER; DEPRESSIVE DISORDER, MAJOR; FEMALE; GENE FREQUENCY; GENOTYPE; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; SUBSTANCE P;

EID: 25844513938     PISSN: 14611457     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1461145705005444     Document Type: Article

References (35)

1. Alderborn A, Kristofferson A, Hammerling U (2000). Determination of single-nucleotide polymorphisms by real-time pyrophosphate DNA sequencing. Genome Research 10, 1249-1258.
2. APA (1994). Diagnostic and Statistical Manual for Mental Disorders. Washington, DC: American Psychiatric Association.
3. Arinami T, Li L, Mitsushio H, Itokawa M, Hamaguchi H, Toru M (1996). An insertion/deletion polymorphism in the angiotensin converting enzyme gene is associated with both brain substance P contents and affective disorders. Biological Psychiatry 40, 1122-1127.
4. Baghai TC, Schule C, Zwanzger P, Minov C, Schwarz MJ, de Jonge S, Rupprecht R, Bondy B (2001). Possible influence of the insertion/deletion polymorphism in the Angiotensin I-converting enzyme gene on therapeutic outcome in affective disorders. Molecular Psychiatry 6, 258-259.
5. Baghai TC, Schule C, Zwanzger P, Minov C, Zill P, Ella R, Eser D, Oezer S, Bondy B, Rupprecht R (2002). Hypothalamic-pituitary-adrenocortical axis dysregulation in patients with major depression is influenced by the insertion/deletion polymorphism in the angiotensin I-converting enzyme gene. Neuroscience Letters 328, 299-303.
6. Baghai TC, Schule C, Zill P, Deiml T, Eser D, Zwanzger P, Ella R, Rupprecht R, Bondy B (2004). The angiotensin I converting enzyme insertion/deletion polymorphism influences therapeutic outcome in major depressed women, but not in men. Neuroscience Letters 363, 38-42.
7. Berrettini WH, Rubinow DR, Nurnberger Jr. JI, Simmons-Alling S, Post RM, Gershon ES (1985). CSF substance P immunoreactivity in affective disorders. Biological Psychiatry 20, 965-970.
8. Bondy B, Baghai TC, Minov C, Schule C, Schwarz MJ, Zwanzger P, Rupprecht R, Moller HJ (2003). Substance P serum levels are increased in major depression: preliminary results. Biological Psychiatry 53, 538-542.
9. Bondy B, Baghai TC, Zill P, Bottlender R, Jaeger M, Minov C, Schule C, Zwanzger P, Rupprecht R, Engel RR (2002). Combined action of the ACE D- and the G-protein beta3 T-allele in major depression: a possible link to cardiovascular disease? Molecular Psychiatry 7, 1120-1126.
10. Evans AE, Poirier O, Kee F, Lecerf L, McCrum E, Falconer T, Crane J, O'Rourke DF, Cambien F (1994). Polymorphisms of the angiotensin-converting- enzyme gene in subjects who die rom coronary heart disease. Quarterly Journal of Medicine 87, 211-214.
11. Farrall M, Keavney B, McKenzie C, Delepine M, Matsuda F, Lathrop GM (1999). Fine-mapping of an ancestral recombination breakpoint in DCP1. Nature Genetics 23, 270-271.
12. Furlong RA, Keramatipour M, Ho LW, Rubinsztein JS, Michael A, Walsh C, Paykel ES, Rubinsztein DC (2000). No association of an insertion/deletion polymorphism in the angiotensin I converting enzyme gene with bipolar or unipolar affective disorders. American Journal of Medical Genetics 96, 733-735.
13. Hong CJ, Wang YC, Tsai SJ (2002). Association study of angiotensin I-converting enzyme polymorphism and symptomatology and antidepressant response in major depressive disorders. Journal of Neural Transmission 109, 1209-1214.
14. Kramer MS, Cutler N, Feighner J, Shrivastava R, Carman J, Sramek JJ, Reines SA, Liu G, Snavely D, Wyatt-Knowles E, Hale JJ, Mills SG, MacCoss M, Swain CJ, Harrison T, Hill RG, Hefti F, Scolnick EM, Cascieri MA, Chicchi GG, Sadowski S, Williams AR, Hewson L, Smith D, Rupniak NM (1998). Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science 281, 1640-1645.
15. Kramer MS, Winokur A, Kelsey J, Preskorn SH, Rothschild AJ, Snavely D, Ghosh K, Ball WA, Reines SA, Munjack D, Apter JT, Cunningham L, Kling M, Bari M, Getson A, Lee Y (2004). Demonstration of the efficacy and safety of a novel substance P (NK1) receptor antagonist in major depression. Neuropsychopharmacology 29, 385-392.
16. Lerer B, Macciardi F (2002). Pharmacogenetics of antidepressant and mood-stabilizing drugs: a review of candidate-gene studies and future research directions. International Journal of Neuropsychopharmacology 5, 255-275.
17. Martensson B, Nyberg S, Toresson G, Brodin E, Bertilsson L (1989). Fluoxetine treatment of depression. Clinical effects, drug concentrations and monoamine metabolites and N-terminally extended substance P in cerebrospinal fluid. Acta Psychiatrica Scandinavica 79, 586-596.
18. McGuffin P, Rijsdijk F, Andrew M, Sham P, Katz R, Cardno A (2003). The heritability of bipolar affective disorder and the genetic relationship to unipolar depression. Archives of General Psychiatry 60, 497-502.
19. Meira-Lima IV, Pereira AC, Mota GF, Krieger JE, Vallada H (2000). Angiotensinogen and angiotensin converting enzyme gene polymorphisms and the risk of bipolar affective disorder in humans. Neuroscience Letters 293, 103-106.
20. Mendlewicz J (1994). The search for a manic depressive gene: from classical to molecular genetics. Progress in Brain Research 100, 255-259.
21. Merck & Co. Inc. (2003). Merck News item (http://www.merck.com/ newsroom/press_releases/research_and_development/2003_1112.html).
22. Ogden CA, Rich ME, Schork NJ, Paulus MP, Geyer MA, Lohr JB, Kuczenski R, Niculescu AB (2004). Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach. Molecular Psychiatry. DOI: 10.1038/sj.mp.4001547.
23. Pauls J, Bandelow B, Ruther E, Kornhuber J (2000). Polymorphism of the gene of angiotensin converting enzyme: lack of association with mood disorder. Journal of Neural Transmission 107, 1361-1366.
24. Raymond M, Rousset F (1995). GENEPOP (version 1.2): a population genetics software for exact tests and ecumenicism. Journal of Heredity 86, 248-249.
25. Rieder MJ, Taylor SL, Clark AG, Nickerson DA (1999). Sequence variation in the human angiotensin converting enzyme. Nature Genetics 22, 59-62.
26. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F (1990). An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. Journal of Clinical Investigation 86, 1343-1346.
27. Rimon R, Le Greves P, Nyberg F, Heikkila L, Salmela L, Terenius L (1984). Elevation of substance P-like peptides in the CSF of psychiatric patients. Biological Psychiatry 19, 509-516.
28. Rupniak NM, Kramer MS (1999). Discovery of the antidepressant and anti-emetic efficacy of substance P receptor (NK1) antagonists. Trends in Pharmacological Sciences 20, 485-490.
29. Segman RH, Shapira Y, Modai I, Hamdan A, Zislin J, Heresco-Levy U, Kanyas K, Hirschmann S, Karni O, Finkel B, Schlafman M, Lerner A, Shapira B, Macciardi F, Lerer B (2002). Angiotensin converting enzyme gene insertion/deletion polymorphism: case-control association studies in schizophrenia, major affective disorder, and tardive dyskinesia and a family-based association study in schizophrenia. American Journal of Medical Genetics 114, 310-314.
30. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Hergueta T, Baker R, Dunbar GC (1998). The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. Journal of Clinical Psychiatry 59 (Suppl. 20), 22-33.
31. Soubrier F, Nadaud S, Williams TA (1994). Angiotensin I converting enzyme gene: regulation, polymorphism and implications in cardiovascular diseases. European Heart Journal 15 (Suppl. D), 24-29.
32. StataCorp (2003). Stata Statistical Software: Release 8.0. College Station, TX: Stata Corporation.
33. Underhill PA, Jin L, Lin AA, Mehdi SQ, Jenkins T, Vollrath D, Davis RW, Cavalli-Sforza LL, Oefner PJ (1997). Detection of numerous Y chromosome biallelic polymorphisms by denaturing high-performance liquid chromatography. Genome Research 7, 996-1005.
34. Weckx S, De Rijk P, Van Broeckhoven C, Del-Favero J (2004). SNPbox: web-based high-throughput primer design from gene to genome. Nucleic Acids Research 32 (Suppl. 2), W170-172.
35. Zhu X, Bouzekri N, Southam L, Cooper RS, Adeyemo A, McKenzie CA, Luke A, Chen G, Elston RC, Ward R (2001). Linkage and association analysis of angiotensin I-converting enzyme (ACE)-gene polymorphisms with ACE concentration and blood pressure. American Journal of Human Genetics 68, 1139-1148.