메뉴 건너뛰기




Volumn 40, Issue 2, 2005, Pages 132-139

Human naive CD4 T-Cell clones specific for HIV envelope persist for years in vivo in the absence of antigenic challenge

Author keywords

CD4 cells; HIV gp120; Immunodominant epitope; T lymphocytes; T cell receptors; T cell repertoire

Indexed keywords

CD4 ANTIGEN; EPITOPE; GAMMA INTERFERON; GLYCOPROTEIN GP 120; T LYMPHOCYTE RECEPTOR;

EID: 25844507067     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.qai.0000177842.67392.e2     Document Type: Article
Times cited : (6)

References (49)
  • 1
    • 0030665257 scopus 로고    scopus 로고
    • Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia
    • Rosenberg ES, Billingsley JM, Caliendo AM, et al. Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia. Science. 1997;278:1447-1450.
    • (1997) Science , vol.278 , pp. 1447-1450
    • Rosenberg, E.S.1    Billingsley, J.M.2    Caliendo, A.M.3
  • 2
    • 0034123842 scopus 로고    scopus 로고
    • The role of CD4(+) T helper cells in the cytotoxic T lymphocyte response to HIV-1
    • Altfeld M, Rosenberg ES. The role of CD4(+) T helper cells in the cytotoxic T lymphocyte response to HIV-1. Curr Opin Immunol. 2000;12: 375-380.
    • (2000) Curr Opin Immunol , vol.12 , pp. 375-380
    • Altfeld, M.1    Rosenberg, E.S.2
  • 3
  • 4
    • 0030873556 scopus 로고    scopus 로고
    • Differential requirements for survival and proliferation of CD8 naive or memory T cells
    • Tanchot C, Lemonnier FA, Perarnau B, et al. Differential requirements for survival and proliferation of CD8 naive or memory T cells. Science. 1997; 276:2057-2062.
    • (1997) Science , vol.276 , pp. 2057-2062
    • Tanchot, C.1    Lemonnier, F.A.2    Perarnau, B.3
  • 5
    • 0013854296 scopus 로고
    • Effect of thymectomy in adult mice on immunological responsiveness
    • Miller JF. Effect of thymectomy in adult mice on immunological responsiveness. Nature. 1965;208:1337-1338.
    • (1965) Nature , vol.208 , pp. 1337-1338
    • Miller, J.F.1
  • 6
    • 0029147807 scopus 로고
    • The peripheral T cell repertoire: Independent homeostatic regulation of virgin and activated CD8+ T cell pools
    • Tanchot C, Rocha B. The peripheral T cell repertoire: independent homeostatic regulation of virgin and activated CD8+ T cell pools. Eur J Immunol. 1995;25:2127-2136.
    • (1995) Eur J Immunol , vol.25 , pp. 2127-2136
    • Tanchot, C.1    Rocha, B.2
  • 7
    • 0025902285 scopus 로고
    • Mature murine B and T cells transferred to SCID mice can survive indefinitely and many maintain a virgin phenotype
    • Sprent J, Schaefer M, Hurd M, et al. Mature murine B and T cells transferred to SCID mice can survive indefinitely and many maintain a virgin phenotype. J Exp Med. 1991;174:717-728.
    • (1991) J Exp Med , vol.174 , pp. 717-728
    • Sprent, J.1    Schaefer, M.2    Hurd, M.3
  • 8
    • 0023200330 scopus 로고
    • The stable and permanent expansion of functional T lymphocytes in athymic nude rats after a single injection of mature T cells
    • Bell EB, Sparshott SM, Drayson MT, et al. The stable and permanent expansion of functional T lymphocytes in athymic nude rats after a single injection of mature T cells. J Immunol. 1987;139:1379-1384.
    • (1987) J Immunol , vol.139 , pp. 1379-1384
    • Bell, E.B.1    Sparshott, S.M.2    Drayson, M.T.3
  • 9
    • 0033136944 scopus 로고    scopus 로고
    • Designing and maintaining the mature TCR repertoire: The continuum of self-peptide:self-MHC complex recognition
    • Viret C, Wong FS, Janeway CA Jr. Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition. Immunity. 1999;10;559-568.
    • (1999) Immunity , vol.10 , pp. 559-568
    • Viret, C.1    Wong, F.S.2    Janeway Jr., C.A.3
  • 10
    • 0034080178 scopus 로고    scopus 로고
    • Population biology of lymphocytes: The flight for survival
    • Freitas AA, Rocha B. Population biology of lymphocytes: the flight for survival. Annu Rev Immunol. 2000;18:83-111.
    • (2000) Annu Rev Immunol , vol.18 , pp. 83-111
    • Freitas, A.A.1    Rocha, B.2
  • 11
    • 0028023462 scopus 로고
    • Lymphocyte life-span and memory
    • Sprent J, Tough DF. Lymphocyte life-span and memory. Science. 1994; 265:1395-1400.
    • (1994) Science , vol.265 , pp. 1395-1400
    • Sprent, J.1    Tough, D.F.2
  • 13
    • 0013837449 scopus 로고
    • Unstable chromosome changes in tuberculin-stimulated leukocyte cultures from irradiated patients. Evidence for immunologically committed, long-lived lymphocytes in human blood
    • Nowell PC. Unstable chromosome changes in tuberculin-stimulated leukocyte cultures from irradiated patients. Evidence for immunologically committed, long-lived lymphocytes in human blood. Blood. 1965;26: 798-804.
    • (1965) Blood , vol.26 , pp. 798-804
    • Nowell, P.C.1
  • 14
    • 0014220401 scopus 로고
    • Lymphocyte survival in men treated with x-rays for ankylosing spondylitis
    • Buckton KE, Brown WM, Smith PG. Lymphocyte survival in men treated with x-rays for ankylosing spondylitis. Nature. 1967;214:470-473.
    • (1967) Nature , vol.214 , pp. 470-473
    • Buckton, K.E.1    Brown, W.M.2    Smith, P.G.3
  • 15
    • 0026445567 scopus 로고
    • Lifespan of human lymphocyte subsets defined by CD45 isoforms
    • Michie CA, McLean A, Alcock C, et al. Lifespan of human lymphocyte subsets defined by CD45 isoforms. Nature. 1992;360:264-265.
    • (1992) Nature , vol.360 , pp. 264-265
    • Michie, C.A.1    McLean, A.2    Alcock, C.3
  • 16
    • 0036550559 scopus 로고    scopus 로고
    • Effector and memory T-cell differentiation: Implications for vaccine development
    • Kaech SM, Wherry EJ, Ahmed R. Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol. 2002;2:251-262.
    • (2002) Nat Rev Immunol , vol.2 , pp. 251-262
    • Kaech, S.M.1    Wherry, E.J.2    Ahmed, R.3
  • 17
    • 25844436978 scopus 로고    scopus 로고
    • Measuring antigen specific immune responses: Understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer
    • In press
    • Kern F, Li Pira G, Gratama JW, et al. Measuring antigen specific immune responses: understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer. Trends Immunol. (In press).
    • Trends Immunol
    • Kern, F.1    Li Pira, G.2    Gratama, J.W.3
  • 18
    • 0023720148 scopus 로고
    • T-cell antigen receptor genes and T-cell recognition
    • Davis MM, Bjorkman PJ. T-cell antigen receptor genes and T-cell recognition. Nature. 1988;334:395-402.
    • (1988) Nature , vol.334 , pp. 395-402
    • Davis, M.M.1    Bjorkman, P.J.2
  • 19
    • 0028305255 scopus 로고
    • Virus-specific CD8+ T-cell memory determined by clonal burst size
    • Hou S, Hyland L, Ryan KW, et al. Virus-specific CD8+ T-cell memory determined by clonal burst size. Nature. 1994;369:652-654.
    • (1994) Nature , vol.369 , pp. 652-654
    • Hou, S.1    Hyland, L.2    Ryan, K.W.3
  • 20
    • 0031668697 scopus 로고    scopus 로고
    • Long-term CD4 Th1 and Th2 memory following acute lymphocytic choriomeningitis virus infection
    • Whitmire JK, Asano MS, Murali-Krishna K, et al. Long-term CD4 Th1 and Th2 memory following acute lymphocytic choriomeningitis virus infection. J Virol. 1998;72:8281-8288.
    • (1998) J Virol , vol.72 , pp. 8281-8288
    • Whitmire, J.K.1    Asano, M.S.2    Murali-Krishna, K.3
  • 21
    • 0025829598 scopus 로고
    • The naive repertoire of human T helper cells specific for gp120, the envelope glycoprotein of HIV
    • Manca F, Habeshaw J, Dalgleish A. The naive repertoire of human T helper cells specific for gp120, the envelope glycoprotein of HIV. J Immunol. 1991;146:1964-1971.
    • (1991) J Immunol , vol.146 , pp. 1964-1971
    • Manca, F.1    Habeshaw, J.2    Dalgleish, A.3
  • 22
    • 0026556230 scopus 로고
    • Galactose receptors and presentation of HIV envelope glycoprotein to specific human T cells
    • Manca F. Galactose receptors and presentation of HIV envelope glycoprotein to specific human T cells. J Immunol. 1992;148:2278-2282.
    • (1992) J Immunol , vol.148 , pp. 2278-2282
    • Manca, F.1
  • 23
    • 0028914941 scopus 로고
    • Recognition of human T-leukemia virus (HTLV-1) envelope by human CD4+ T-cell lines from HTLV-1 seronegative individuals: Specificity and clonal heterogeneity
    • Manca F, Li Pira G, Fenoglio D, et al. Recognition of human T-leukemia virus (HTLV-1) envelope by human CD4+ T-cell lines from HTLV-1 seronegative individuals: specificity and clonal heterogeneity. Blood. 1995;85:1547-1554.
    • (1995) Blood , vol.85 , pp. 1547-1554
    • Manca, F.1    Li Pira, G.2    Fenoglio, D.3
  • 24
    • 0029041355 scopus 로고
    • Human T helper cells specific for HIV reverse transcriptase: Possible role in intrastructural help for HIV envelope-specific antibodies
    • Manca F, Fenoglio D, Valle MT, et al. Human T helper cells specific for HIV reverse transcriptase: possible role in intrastructural help for HIV envelope-specific antibodies. Eur J Immunol. 1995;25:1217-1223.
    • (1995) Eur J Immunol , vol.25 , pp. 1217-1223
    • Manca, F.1    Fenoglio, D.2    Valle, M.T.3
  • 25
    • 0027518512 scopus 로고
    • Role of flanking variable sequences in antigenicity of consensus regions of HIV gp120 for recognition by specific human T helper clones
    • Manca F, Habeshaw JA, Dalgleish AG, et al. Role of flanking variable sequences in antigenicity of consensus regions of HIV gp120 for recognition by specific human T helper clones. Eur J Immunol. 1993;23:269-274.
    • (1993) Eur J Immunol , vol.23 , pp. 269-274
    • Manca, F.1    Habeshaw, J.A.2    Dalgleish, A.G.3
  • 26
    • 10244278019 scopus 로고    scopus 로고
    • Antigenicity of HIV-derived T helper determinants in the context of carrier recombinant proteins: Effect on T helper cell repertoire selection
    • Manca F, De Berardinis P, Fenoglio D, et al. Antigenicity of HIV-derived T helper determinants in the context of carrier recombinant proteins: effect on T helper cell repertoire selection. Eur J Immunol. 1996;26:2461-2469.
    • (1996) Eur J Immunol , vol.26 , pp. 2461-2469
    • Manca, F.1    De Berardinis, P.2    Fenoglio, D.3
  • 27
    • 0035452489 scopus 로고    scopus 로고
    • Design of cassette vectors permitting cloning of all types of human TCR variable alpha and beta regions
    • Caivano A, D'Apice L, Tiberio C, et al. Design of cassette vectors permitting cloning of all types of human TCR variable alpha and beta regions. J Immunol Methods. 2001;8875:124-134.
    • (2001) J Immunol Methods , vol.8875 , pp. 124-134
    • Caivano, A.1    D'Apice, L.2    Tiberio, C.3
  • 28
    • 0029847916 scopus 로고    scopus 로고
    • The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: Frequency, specificity, and T-cell receptor usage of pp65-specific CTL
    • Wills MR, Carmichael AJ, Mynard K, et al. The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL. J Virol. 1996;70:7569-7579.
    • (1996) J Virol , vol.70 , pp. 7569-7579
    • Wills, M.R.1    Carmichael, A.J.2    Mynard, K.3
  • 29
    • 2442629552 scopus 로고    scopus 로고
    • Identification of new Th peptides from the cytomegalovirus protein pp65 to design a peptide library for generation of CD4 T cell lines for cellular immunoreconstitution
    • Li Pira G, Bottone L, Ivaldi F, et al. Identification of new Th peptides from the cytomegalovirus protein pp65 to design a peptide library for generation of CD4 T cell lines for cellular immunoreconstitution. Int Immunol 2004;16:635-642.
    • (2004) Int Immunol , vol.16 , pp. 635-642
    • Li Pira, G.1    Bottone, L.2    Ivaldi, F.3
  • 30
    • 11844258837 scopus 로고    scopus 로고
    • Generation of cytomegalovirus specific CD4 T cell lines devoid of alloreactivity using a cocktail of CMV-pp65 peptides for reconstitution of the Th repertoire
    • Li Pira G, Bottone L, Ivaldi F, et al. Generation of cytomegalovirus specific CD4 T cell lines devoid of alloreactivity using a cocktail of CMV-pp65 peptides for reconstitution of the Th repertoire. J Infect Dis. 2005;191:215-226.
    • (2005) J Infect Dis , vol.191 , pp. 215-226
    • Li Pira, G.1    Bottone, L.2    Ivaldi, F.3
  • 32
    • 0029071157 scopus 로고
    • Restricted and conserved T-cell repertoires involved in allorecognition of class II major histocompatibility complex
    • De Palma R, Gorski J. Restricted and conserved T-cell repertoires involved in allorecognition of class II major histocompatibility complex. Proc Natl Acad Sci USA. 1995;92:8836-8840.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8836-8840
    • De Palma, R.1    Gorski, J.2
  • 33
    • 0036499317 scopus 로고    scopus 로고
    • Combination of MHC-peptide multimer-based T cell sorting with the immunoscope permits sensitive ex vivo quantitation and follow-up of human CD8+ T cell immune responses
    • Lim A, Baron V, Ferradini L, et al. Combination of MHC-peptide multimer-based T cell sorting with the immunoscope permits sensitive ex vivo quantitation and follow-up of human CD8+ T cell immune responses. J Immunol Methods. 2002;261:177-194.
    • (2002) J Immunol Methods , vol.261 , pp. 177-194
    • Lim, A.1    Baron, V.2    Ferradini, L.3
  • 34
    • 7444254052 scopus 로고    scopus 로고
    • Therapeutic effectiveness of recombinant cancer vaccines is associated with a prevalent T-cell receptor alpha usage by melanoma-specific CD8+ T lymphocytes
    • De Palma R, Mango I, Del Galdo F, et al. Therapeutic effectiveness of recombinant cancer vaccines is associated with a prevalent T-cell receptor alpha usage by melanoma-specific CD8+ T lymphocytes. Cancer Res. 2004;64:8068-8076.
    • (2004) Cancer Res , vol.64 , pp. 8068-8076
    • De Palma, R.1    Mango, I.2    Del Galdo, F.3
  • 36
    • 0022645825 scopus 로고
    • High frequency and nonrandom distribution of alloreactivity in T cell clones selected for recognition of foreign antigen in association with self class II molecules
    • Ashwell JD, Chen C, Schwartz RH. High frequency and nonrandom distribution of alloreactivity in T cell clones selected for recognition of foreign antigen in association with self class II molecules. J Immunol. 1986;136:389-395.
    • (1986) J Immunol , vol.136 , pp. 389-395
    • Ashwell, J.D.1    Chen, C.2    Schwartz, R.H.3
  • 37
    • 0028200629 scopus 로고
    • Cross-reactivities in memory cytotoxic T lymphocyte recognition of heterologous viruses
    • Selin LK, Nahill SR, Welsh RM. Cross-reactivities in memory cytotoxic T lymphocyte recognition of heterologous viruses. J Exp Med. 1994;179: 1933-1943.
    • (1994) J Exp Med , vol.179 , pp. 1933-1943
    • Selin, L.K.1    Nahill, S.R.2    Welsh, R.M.3
  • 38
    • 0033179273 scopus 로고    scopus 로고
    • On the lifespan of virgin T lymphocytes
    • Di Rosa F, Ramaswamy S, Ridge JP, et al. On the lifespan of virgin T lymphocytes. J Immunol. 1999;163:1253-1257.
    • (1999) J Immunol , vol.163 , pp. 1253-1257
    • Di Rosa, F.1    Ramaswamy, S.2    Ridge, J.P.3
  • 39
    • 0032728738 scopus 로고    scopus 로고
    • Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease
    • Hemmer B, Gran B, Zhao Y, et al. Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease. Nat Med. 1999; 5:1375-1382.
    • (1999) Nat Med , vol.5 , pp. 1375-1382
    • Hemmer, B.1    Gran, B.2    Zhao, Y.3
  • 40
    • 0026004883 scopus 로고
    • T cell responses to peptides covering the gag p24 region of HIV-1 occur in HIV-1 seronegative individuals
    • Vyakarnam A, Matear PM, Cranenburg C, et al. T cell responses to peptides covering the gag p24 region of HIV-1 occur in HIV-1 seronegative individuals. Int Immunol. 1991;3:939-947.
    • (1991) Int Immunol , vol.3 , pp. 939-947
    • Vyakarnam, A.1    Matear, P.M.2    Cranenburg, C.3
  • 41
    • 0036636119 scopus 로고    scopus 로고
    • Characterization of human immunodeficiency virus type 1 (HIV-1) Gag- and Gag peptide-specific CD4(+) T-cell clones from an HIV-1-seronegative donor following in vitro immunization
    • Venturini S, Mosier DE, Burton DR, et al. Characterization of human immunodeficiency virus type 1 (HIV-1) Gag- and Gag peptide-specific CD4(+) T-cell clones from an HIV-1-seronegative donor following in vitro immunization. J Virol. 2002;76:6987-6999.
    • (2002) J Virol , vol.76 , pp. 6987-6999
    • Venturini, S.1    Mosier, D.E.2    Burton, D.R.3
  • 42
    • 0035902513 scopus 로고    scopus 로고
    • IL-7 is critical for homeostatic proliferation and survival of naive T cells
    • Tan JT, Dudl E, LeRoy E, et al. IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci USA. 2001; 98:8732-8737.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8732-8737
    • Tan, J.T.1    Dudl, E.2    Leroy, E.3
  • 43
    • 0034332403 scopus 로고    scopus 로고
    • Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
    • Schluns KS, Kieper WC, Jameson SC, et al. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat Immunol. 2000;1:426-432.
    • (2000) Nat Immunol , vol.1 , pp. 426-432
    • Schluns, K.S.1    Kieper, W.C.2    Jameson, S.C.3
  • 44
    • 0035892904 scopus 로고    scopus 로고
    • Cutting edge: Secondary lymphoid organs are essential for maintaining the CD4, but not CD8, naive T cell pool
    • Dai Z, Lakkis FG. Cutting edge: secondary lymphoid organs are essential for maintaining the CD4, but not CD8, naive T cell pool. J Immunol. 2001;167:6711-6715.
    • (2001) J Immunol , vol.167 , pp. 6711-6715
    • Dai, Z.1    Lakkis, F.G.2
  • 45
    • 0022579722 scopus 로고
    • The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition
    • Kronenberg M, Siu G, Hood LE, et al. The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition. Annu Rev Immunol. 1986; 4:529-591.
    • (1986) Annu Rev Immunol , vol.4 , pp. 529-591
    • Kronenberg, M.1    Siu, G.2    Hood, L.E.3
  • 46
    • 0025325169 scopus 로고
    • T cell receptor gene diversity and selection
    • Davis MM. T cell receptor gene diversity and selection. Annu Rev Biochem. 1990;59:475-496.
    • (1990) Annu Rev Biochem , vol.59 , pp. 475-496
    • Davis, M.M.1
  • 47
    • 0032973455 scopus 로고    scopus 로고
    • In vivo migration and function of transferred HIV-1-specific cytotoxic T cells
    • Brodie SJ, Lewinsohn DA, Patterson BK, et al. In vivo migration and function of transferred HIV-1-specific cytotoxic T cells. Nat Med. 1999;5: 34-41.
    • (1999) Nat Med , vol.5 , pp. 34-41
    • Brodie, S.J.1    Lewinsohn, D.A.2    Patterson, B.K.3
  • 48
    • 3242751959 scopus 로고    scopus 로고
    • Rapid turnover of effector-memory CD4(+) T cells in healthy humans
    • Macallan DC, Wallace D, Zhang Y, et al. Rapid turnover of effector-memory CD4(+) T cells in healthy humans. J Exp Med. 2004;200:255-260.
    • (2004) J Exp Med , vol.200 , pp. 255-260
    • Macallan, D.C.1    Wallace, D.2    Zhang, Y.3
  • 49
    • 3543104811 scopus 로고    scopus 로고
    • Beyond help: Direct effector functions of human immunodeficiency virus type 1-specific CD4(+) T cells
    • Norris PJ, Moffett HF, Yang OO, et al. Beyond help: direct effector functions of human immunodeficiency virus type 1-specific CD4(+) T cells. J Virol. 2004;78:8844-8851.
    • (2004) J Virol , vol.78 , pp. 8844-8851
    • Norris, P.J.1    Moffett, H.F.2    Yang, O.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.