-
2
-
-
0037314229
-
New insights into the pathogenesis of asthma
-
J.A. Elias, C.G. Lee, T. Zheng, B. Ma, R.J. Homer, and Z. Zhu New insights into the pathogenesis of asthma J Clin Invest 111 2003 291 297
-
(2003)
J Clin Invest
, vol.111
, pp. 291-297
-
-
Elias, J.A.1
Lee, C.G.2
Zheng, T.3
Ma, B.4
Homer, R.J.5
Zhu, Z.6
-
3
-
-
0036284984
-
The role of Th1/Th2 polarization in mucosal immunity
-
M.F. Neurath, S. Finotto, and L.H. Glimcher The role of Th1/Th2 polarization in mucosal immunity Nat Med 8 2002 567 573
-
(2002)
Nat Med
, vol.8
, pp. 567-573
-
-
Neurath, M.F.1
Finotto, S.2
Glimcher, L.H.3
-
4
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
G. Trinchieri Interleukin-12 and the regulation of innate resistance and adaptive immunity Nat Rev Immunol 3 2003 133 146
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
5
-
-
0024467154
-
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
-
M. Kobayashi, L. Fitz, M. Ryan, R.M. Hewick, S.C. Clark, and S. Chan Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes J Exp Med 170 1989 827 845
-
(1989)
J Exp Med
, vol.170
, pp. 827-845
-
-
Kobayashi, M.1
Fitz, L.2
Ryan, M.3
Hewick, R.M.4
Clark, S.C.5
Chan, S.6
-
6
-
-
0028967287
-
Mouse interleukin-12 (IL-12) p40 homodimer: A potent IL-12 antagonist
-
S. Gillessen, D. Carvajal, P. Ling, F.J. Podlaski, D.L. Stremlo, and P.C. Familletti Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist Eur J Immunol 25 1995 200 206
-
(1995)
Eur J Immunol
, vol.25
, pp. 200-206
-
-
Gillessen, S.1
Carvajal, D.2
Ling, P.3
Podlaski, F.J.4
Stremlo, D.L.5
Familletti, P.C.6
-
7
-
-
0028819316
-
Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity
-
P. Ling, M.K. Gately, U. Gubler, A.S. Stern, P. Lin, and K. Hollfelder Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity J Immunol 154 1995 116 127
-
(1995)
J Immunol
, vol.154
, pp. 116-127
-
-
Ling, P.1
Gately, M.K.2
Gubler, U.3
Stern, A.S.4
Lin, P.5
Hollfelder, K.6
-
8
-
-
0031132212
-
In vivo production and function of IL-12 p40 homodimers
-
F.P. Heinzel, A.M. Hujer, F.N. Ahmed, and R.M. Rerko In vivo production and function of IL-12 p40 homodimers J Immunol 158 1997 4381 4388
-
(1997)
J Immunol
, vol.158
, pp. 4381-4388
-
-
Heinzel, F.P.1
Hujer, A.M.2
Ahmed, F.N.3
Rerko, R.M.4
-
9
-
-
0032991684
-
Characterization of mouse interleukin-12 p40 homodimer binding to the interleukin-12 receptor subunits
-
X. Wang, V.L. Wilkinson, F.J. Podlaski, C. Wu, A.S. Stern, and D.H. Presky Characterization of mouse interleukin-12 p40 homodimer binding to the interleukin-12 receptor subunits Eur J Immunol 29 1999 2007 2013
-
(1999)
Eur J Immunol
, vol.29
, pp. 2007-2013
-
-
Wang, X.1
Wilkinson, V.L.2
Podlaski, F.J.3
Wu, C.4
Stern, A.S.5
Presky, D.H.6
-
10
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
B. Oppmann, R. Lesley, B. Blom, J.C. Timans, Y. Xu, and B. Hunte Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12 Immunity 13 2000 715 725
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
Timans, J.C.4
Xu, Y.5
Hunte, B.6
-
11
-
-
0031964713
-
Reduced T helper 1 responses in IL-12 p40 transgenic mice
-
T. Yoshimoto, C.R. Wang, T. Yoneto, S. Waki, S. Sunaga, and Y. Komagata Reduced T helper 1 responses in IL-12 p40 transgenic mice J Immunol 160 1998 588 594
-
(1998)
J Immunol
, vol.160
, pp. 588-594
-
-
Yoshimoto, T.1
Wang, C.R.2
Yoneto, T.3
Waki, S.4
Sunaga, S.5
Komagata, Y.6
-
12
-
-
1642407761
-
Pathological role of large intestinal IL-12 p40 for the induction of Th2-type allergic diarrhea
-
A. Hino, M.N. Kweon, K. Fujihashi, J.R. McGhee, and H. Kiyono Pathological role of large intestinal IL-12 p40 for the induction of Th2-type allergic diarrhea Am J Pathol 164 2004 1327 1335
-
(2004)
Am J Pathol
, vol.164
, pp. 1327-1335
-
-
Hino, A.1
Kweon, M.N.2
Fujihashi, K.3
McGhee, J.R.4
Kiyono, H.5
-
13
-
-
0035808784
-
Interleukin 12 p40 production by barrier epithelial cells during airway inflammation
-
M.J. Walter, N. Kajiwara, P. Karanja, M. Castro, and M.J. Holtzman Interleukin 12 p40 production by barrier epithelial cells during airway inflammation J Exp Med 193 2001 339 351
-
(2001)
J Exp Med
, vol.193
, pp. 339-351
-
-
Walter, M.J.1
Kajiwara, N.2
Karanja, P.3
Castro, M.4
Holtzman, M.J.5
-
14
-
-
0034210234
-
Significant evidence for linkage of mite-sensitive childhood asthma to chromosome 5q31-q33 near the interleukin 12 B locus by a genome-wide search in Japanese families
-
Y. Yokouchi, Y. Nukaga, M. Shibasaki, E. Noguchi, K. Kimura, and S. Ito Significant evidence for linkage of mite-sensitive childhood asthma to chromosome 5q31-q33 near the interleukin 12 B locus by a genome-wide search in Japanese families Genomics 66 2000 152 160
-
(2000)
Genomics
, vol.66
, pp. 152-160
-
-
Yokouchi, Y.1
Nukaga, Y.2
Shibasaki, M.3
Noguchi, E.4
Kimura, K.5
Ito, S.6
-
15
-
-
0028230946
-
Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin e concentrations
-
D.G. Marsh, J.D. Neely, D.R. Breazeale, B. Ghosh, L.R. Freidhoff, and E. Ehrlich-Kautzky Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations Science 264 1994 1152 1156
-
(1994)
Science
, vol.264
, pp. 1152-1156
-
-
Marsh, D.G.1
Neely, J.D.2
Breazeale, D.R.3
Ghosh, B.4
Freidhoff, L.R.5
Ehrlich-Kautzky, E.6
-
16
-
-
0027957091
-
Evidence for a locus regulating total serum IgE levels mapping to chromosome 5
-
D.A. Meyers, D.S. Postma, C.I. Panhuysen, J. Xu, P.J. Amelung, and R.C. Levitt Evidence for a locus regulating total serum IgE levels mapping to chromosome 5 Genomics 23 1994 464 470
-
(1994)
Genomics
, vol.23
, pp. 464-470
-
-
Meyers, D.A.1
Postma, D.S.2
Panhuysen, C.I.3
Xu, J.4
Amelung, P.J.5
Levitt, R.C.6
-
17
-
-
0035864817
-
Linkage and allelic association of chromosome 5 cytokine cluster genetic markers with atopy and asthma associated traits
-
A.J. Walley, S. Wiltshire, C.M. Ellis, and W.O. Cookson Linkage and allelic association of chromosome 5 cytokine cluster genetic markers with atopy and asthma associated traits Genomics 72 2001 15 20
-
(2001)
Genomics
, vol.72
, pp. 15-20
-
-
Walley, A.J.1
Wiltshire, S.2
Ellis, C.M.3
Cookson, W.O.4
-
18
-
-
0035179393
-
Factor analysis of asthma and atopy traits shows 2 major components, one of which is linked to markers on chromosome 5q
-
C.J. Holberg, M. Halonen, S. Solomon, P.E. Graves, M. Baldini, and R.P. Erickson Factor analysis of asthma and atopy traits shows 2 major components, one of which is linked to markers on chromosome 5q J Allergy Clin Immunol 108 2001 772 780
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 772-780
-
-
Holberg, C.J.1
Halonen, M.2
Solomon, S.3
Graves, P.E.4
Baldini, M.5
Erickson, R.P.6
-
19
-
-
0037055708
-
Association of IL12B promoter polymorphism with severity of atopic and non-atopic asthma in children
-
G. Morahan, D. Huang, M. Wu, B.J. Holt, G.P. White, and G.E. Kendall Association of IL12B promoter polymorphism with severity of atopic and non-atopic asthma in children Lancet 360 2002 455 459
-
(2002)
Lancet
, vol.360
, pp. 455-459
-
-
Morahan, G.1
Huang, D.2
Wu, M.3
Holt, B.J.4
White, G.P.5
Kendall, G.E.6
-
20
-
-
4544287247
-
The IL12B gene is associated with asthma
-
A.G. Randolph, C. Lange, E.K. Silverman, R. Lazarus, E.S. Silverman, and B. Raby The IL12B gene is associated with asthma Am J Hum Genet 75 2004 709 715
-
(2004)
Am J Hum Genet
, vol.75
, pp. 709-715
-
-
Randolph, A.G.1
Lange, C.2
Silverman, E.K.3
Lazarus, R.4
Silverman, E.S.5
Raby, B.6
-
21
-
-
1542616269
-
Associations of the IL12B promoter polymorphism in longitudinal data from asthmatic patients 7 to 42 years of age
-
S.K. Khoo, C.M. Hayden, M. Roberts, E. Horak, N. de Klerk, and G. Zhang Associations of the IL12B promoter polymorphism in longitudinal data from asthmatic patients 7 to 42 years of age J Allergy Clin Immunol 113 2004 475 481
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 475-481
-
-
Khoo, S.K.1
Hayden, C.M.2
Roberts, M.3
Horak, E.4
De Klerk, N.5
Zhang, G.6
-
22
-
-
0026230417
-
National Heart, Lung, and Blood Institute Guidelines for the diagnosis and management of asthma. National Heart, Lung, and Blood Institute. National Asthma Education Program. Expert Panel Report
-
National Heart, Lung, and Blood Institute Guidelines for the diagnosis and management of asthma. National Heart, Lung, and Blood Institute. National Asthma Education Program. Expert Panel Report J Allergy Clin Immunol 88 1991 425 524
-
(1991)
J Allergy Clin Immunol
, vol.88
, pp. 425-524
-
-
-
23
-
-
4544359328
-
Variations in the C3, C3a receptor, and C5 genes affect susceptibility to bronchial asthma
-
K. Hasegawa, M. Tamari, C. Shao, M. Shimizu, N. Takahashi, and X.Q. Mao Variations in the C3, C3a receptor, and C5 genes affect susceptibility to bronchial asthma Hum Genet 115 2004 295 301
-
(2004)
Hum Genet
, vol.115
, pp. 295-301
-
-
Hasegawa, K.1
Tamari, M.2
Shao, C.3
Shimizu, M.4
Takahashi, N.5
Mao, X.Q.6
-
24
-
-
0035513445
-
Identification of missense mutation in the IL12B gene: Lack of association between IL12B polymorphisms and asthma and allergic rhinitis in the Japanese population
-
E. Noguchi, Y. Yokouchi, M. Shibasaki, M. Kamioka, K. Yamakawa-Kobayashi, and A. Matsui Identification of missense mutation in the IL12B gene: lack of association between IL12B polymorphisms and asthma and allergic rhinitis in the Japanese population Genes Immun 2 2001 401 403
-
(2001)
Genes Immun
, vol.2
, pp. 401-403
-
-
Noguchi, E.1
Yokouchi, Y.2
Shibasaki, M.3
Kamioka, M.4
Yamakawa-Kobayashi, K.5
Matsui, A.6
-
25
-
-
2342480580
-
Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro
-
K. Ozaki, K. Inoue, H. Sato, A. Iida, Y. Ohnishi, and A. Sekine Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro Nature 429 2004 72 75
-
(2004)
Nature
, vol.429
, pp. 72-75
-
-
Ozaki, K.1
Inoue, K.2
Sato, H.3
Iida, A.4
Ohnishi, Y.5
Sekine, A.6
-
26
-
-
0042667153
-
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis
-
A. Suzuki, R. Yamada, X. Chang, S. Tokuhiro, T. Sawada, and M. Suzuki Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis Nat Genet 34 2003 395 402
-
(2003)
Nat Genet
, vol.34
, pp. 395-402
-
-
Suzuki, A.1
Yamada, R.2
Chang, X.3
Tokuhiro, S.4
Sawada, T.5
Suzuki, M.6
-
27
-
-
0036137018
-
Nucleotide diversity and haplotype structure of the human angiotensinogen gene in two populations
-
T. Nakajima, L.B. Jorde, T. Ishigami, S. Umemura, M. Emi, and J.M. Lalouel Nucleotide diversity and haplotype structure of the human angiotensinogen gene in two populations Am J Hum Genet 70 2002 108 123
-
(2002)
Am J Hum Genet
, vol.70
, pp. 108-123
-
-
Nakajima, T.1
Jorde, L.B.2
Ishigami, T.3
Umemura, S.4
Emi, M.5
Lalouel, J.M.6
-
28
-
-
0242691208
-
A comparison of bayesian methods for haplotype reconstruction from population genotype data
-
M. Stephens, and P. Donnelly A comparison of bayesian methods for haplotype reconstruction from population genotype data Am J Hum Genet 73 2003 1162 1169
-
(2003)
Am J Hum Genet
, vol.73
, pp. 1162-1169
-
-
Stephens, M.1
Donnelly, P.2
-
29
-
-
0036138183
-
Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms
-
T. Niu, Z.S. Qin, X. Xu, and J.S. Liu Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms Am J Hum Genet 70 2002 157 169
-
(2002)
Am J Hum Genet
, vol.70
, pp. 157-169
-
-
Niu, T.1
Qin, Z.S.2
Xu, X.3
Liu, J.S.4
-
30
-
-
0036950351
-
Single nucleotide polymorphisms in innate immunity genes: Abundant variation and potential role in complex human disease
-
R. Lazarus, D. Vercelli, L.J. Palmer, W.J. Klimecki, E.K. Silverman, and B. Richter Single nucleotide polymorphisms in innate immunity genes: abundant variation and potential role in complex human disease Immunol Rev 190 2002 9 25
-
(2002)
Immunol Rev
, vol.190
, pp. 9-25
-
-
Lazarus, R.1
Vercelli, D.2
Palmer, L.J.3
Klimecki, W.J.4
Silverman, E.K.5
Richter, B.6
-
31
-
-
8844239134
-
Association of the hCLCA1 gene with childhood and adult asthma
-
F. Kamada, Y. Suzuki, C. Shao, M. Tamari, K. Hasegawa, and T. Hirota Association of the hCLCA1 gene with childhood and adult asthma Genes Immun 5 2004 540 547
-
(2004)
Genes Immun
, vol.5
, pp. 540-547
-
-
Kamada, F.1
Suzuki, Y.2
Shao, C.3
Tamari, M.4
Hasegawa, K.5
Hirota, T.6
-
33
-
-
0037312921
-
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
-
K.E. Lohmueller, C.L. Pearce, M. Pike, E.S. Lander, and J.N. Hirschhorn Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease Nat Genet 33 2003 177 182
-
(2003)
Nat Genet
, vol.33
, pp. 177-182
-
-
Lohmueller, K.E.1
Pearce, C.L.2
Pike, M.3
Lander, E.S.4
Hirschhorn, J.N.5
-
34
-
-
1542721504
-
Toll-like receptor 2 as a major gene for asthma in children of European farmers
-
W. Eder, W. Klimecki, L. Yu, E. von Mutius, J. Riedler, and C. Braun-Fahrlander ALEX Study Team Toll-like receptor 2 as a major gene for asthma in children of European farmers J Allergy Clin Immunol 113 2004 482 488
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 482-488
-
-
Eder, W.1
Klimecki, W.2
Yu, L.3
Von Mutius, E.4
Riedler, J.5
Braun-Fahrlander, C.6
|