Fibrodysplasia ossificans progressiva and progressive osseous heteroplasia: Two genetic disorders of heterotopic ossification

Clinical Reviews in Bone and Mineral Metabolism

Volumn 3, Issue 3-4, 2005, Pages 257-259

  Shore, Eileen M ^a,b   Kaplan, Frederick S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b 424 Stemmler Hall ^*  (United States)

Author keywords

Fibrodysplasia ossificans progressiva (FOP); Heterotopic ossification; Progressive osseous heteroplasia (POH)

Indexed keywords

ALLELE; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; BONE MALFORMATION; CELL DIFFERENTIATION; CLINICAL EXAMINATION; CLINICAL FEATURE; CONGENITAL MALFORMATION; DIAGNOSTIC ERROR; DIAGNOSTIC PROCEDURE; DISEASE COURSE; DISEASE TRANSMISSION; EDEMA; ENCHONDRAL OSSIFICATION; GENE; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENETIC ANALYSIS; GENETIC DISORDER; GENETIC PROCEDURES; GENOME IMPRINTING; GNAS GENE; HETEROTOPIC OSSIFICATION; HISTOPATHOLOGY; HUMAN; INFLAMMATION; MEMBRANE; MOLECULAR BIOLOGY; OSSIFICATION; OSSIFYING MYOSITIS; PARENT; PATHOGENESIS; PREDICTION; PROGRESSIVE OSSEOUS HETEROPLASIA; SKELETON MALFORMATION; SKIN DISEASE;

EID: 25844491030     PISSN: 15348644     EISSN: None     Source Type: Journal    
DOI: 10.1385/BMM:3:3-4:257     Document Type: Article

References (10)

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7. Feldman G, Li M, Martin S, et al. 2000 Fibrodysplasia ossificans progressiva, a heritable disorder of severe heterotopic ossification, maps to human chromosome 4q27-31. Am J Hum Genet 66:128-135.
8. Weinstein LS, Yu S, Warner DR, Liu J. 2001 Endocrine manifestations of stimulatory G protein alpha-subunit mutations and the role of genomic imprinting. Endocr Rev 22:675-705.
9. Bastepe M, Juppner H. 2005 GNAS locus and pseudohypoparathyroidism. Hormone Res 63:65-74.
10. Lietman SA, Ding C, Cooke DW, Levine MA. 2005 Reduction in Gs alpha induces osteogenic differentiation in human mesenchymal stem cells. Clin Orthop 434: 231-238.