Subcutaneous Interferon-β injections in patients with multiple sclerosis initiate inflammatory skin reactions by local chemokine induction

Journal of Neuroimmunology

Volumn 168, Issue 1-2, 2005, Pages 175-182

  Buttmann, Mathias ^a   Goebeler, Matthias ^b   Toksoy, Atiye ^a   Schmid, Sybille ^a   Graf, Wolfgang ^a   Berberich Siebelt, Friederike ^a   Rieckmann, Peter ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Adverse effects; CXC chemokine IP 10; Interferon ; Monocyte chemoattractant protein 1; Skin

Indexed keywords

BETA1A INTERFERON; CHEMOKINE; RECOMBINANT BETA INTERFERON;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EXTRAVASATION; FEMALE; HUMAN; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MALE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN BIOPSY; SKIN CELL; SKIN INFLAMMATION; T LYMPHOCYTE;

ANTIGENS, CD; BIOPSY; CELLS, CULTURED; CHEMOKINES; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INJECTIONS, SUBCUTANEOUS; INTERFERON-BETA; MALE; MULTIPLE SCLEROSIS; SKIN;

EID: 25844482090     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2005.07.011     Document Type: Article

References (40)

1. C. Avolio, F. Giuliani, G.M. Liuzzi, M. Ruggieri, D. Paolicelli, P. Riccio, P. Livrea, and M. Trojano Adhesion molecules and matrix metalloproteinases in multiple sclerosis: effects induced by Interferon-beta Brain Res. Bull. 61 2003 357 364
2. F. Berard, S. Canillot, B. Balme, and H. Perrot Local cutaneous necrosis after injection of interferon beta Ann. Dermatol. Venereol. 122 1995 105 107
3. C. Bogdan The function of type I interferons in antimicrobial immunity Curr. Opin. Immunol. 12 2000 419 424
4. R. Bonecchi, G. Bianchi, P.P. Bordignon, D. D'Ambrosio, R. Lang, A. Borsatti, S. Sozzani, P. Allavena, P.A. Gray, A. Mantovani, and F. Sinigaglia Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s J. Exp. Med. 187 1998 129 134
5. M. Buttmann, M. Goebeler, and P. Rieckmann Local pain during REBIF injection is not due to acidic pH J. Neurol. Neurosurg. Psychiatry 75 2004 1078
6. M. Buttmann, C. Merzyn, and P. Rieckmann Interferon-beta induces transient systemic IP-10/CXCL10 chemokine release in patients with multiple sclerosis J. Neuroimmunol. 156 2004 195 203
7. M.W. Carr, S.J. Roth, E. Luther, S.S. Rose, and T.A. Springer Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant Proc. Natl. Acad. Sci. U. S. A. 91 1994 3652 3656
8. F. Casoni, E. Merelli, R. Bedin, A. Martella, A. Cesinaro, and A. Bertolotto Necrotizing skin lesions and NABs development in a multiple sclerosis patient treated with IFNbeta 1b Mult. Scler. 9 2003 420 423
9. F. Cnudde, S. Gharakhanian, J. Luboinski, J. Dry, and W. Rozenbaum Cutaneous local necrosis following interferon injections Int. J. Dermatol. 30 1991 147
10. A. Compston, and A. Coles Multiple sclerosis Lancet 359 2002 1221 1231
11. I. Cremer, J. Ghysdael, and V. Vieillard A non-classical ISRE/ISGF3 pathway mediates induction of RANTES gene transcription by type I IFNs FEBS Lett. 511 2002 41 45
12. O. Fahy, H. Porte, S. Senechal, H. Vorng, A.R. McEuen, M.G. Buckley, A.F. Walls, B. Wallaert, A.B. Tonnel, and A. Tsicopoulos Chemokine-induced cutaneous inflammatory cell infiltration in a model of Hu-PBMC-SCID mice grafted with human skin Am. J. Pathol. 158 2001 1053 1063
13. L. Fantuzzi, I. Canini, F. Belardelli, and S. Gessani IFN-beta stimulates the production of beta-chemokines in human peripheral blood monocytes. Importance of macrophage differentiation Eur. Cytokine Netw. 12 2001 597 603
14. R. Feldmann, H. Low-Weiser, P. Duschet, and F. Gschnait Necrotizing cutaneous lesions caused by interferon beta injections in a patient with multiple sclerosis Dermatology 195 1997 52 53
15. G.R. Foster, S.H. Masri, R. David, M. Jones, A. Datta, G. Lombardi, L. Runkell, C. de Dios, I. Sizing, M.J. James, and F.M. Marelli-Berg IFN-alpha subtypes differentially affect human T cell motility J. Immunol. 173 2004 1663 1670
16. M.E. Fuentes, S.K. Durham, M.R. Swerdel, A.C. Lewin, D.S. Barton, J.R. Megill, R. Bravo, and S.A. Lira Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1 J. Immunol. 155 1995 5769 5776
17. M. Goebeler, A. Trautmann, A. Voss, E.V. Brocker, A. Toksoy, and R. Gillitzer Differential and sequential expression of multiple chemokines during elicitation of allergic contact hypersensitivity Am. J. Pathol. 158 2001 431 440
18. N. Grigoriadis Interferon beta treatment in relapsing-remitting multiple sclerosis. A review Clin. Neurol. Neurosurg. 104 2002 251 258
19. R. Kitai, M.L. Zhao, N. Zhang, L.L. Hua, and S.C. Lee Role of MIP-1beta and RANTES in HIV-1 infection of microglia: inhibition of infection and induction by IFNbeta J. Neuroimmunol. 110 2000 230 239
20. R. Kunstfeld, S. Lechleitner, K. Wolff, and P. Petzelbauer MCP-1 and MIP-1alpha are most efficient in recruiting T cells into the skin in vivo J. Invest. Dermatol. 111 1998 1040 1044
21. M.T. Liu, B.P. Chen, P. Oertel, M.J. Buchmeier, D. Armstrong, T.A. Hamilton, and T.E. Lane The T cell chemoattractant IFN-inducible protein 10 is essential in host defense against viral-induced neurologic disease J. Immunol. 165 2000 2327 2330
22. P. Loetscher, M. Seitz, I. Clark-Lewis, M. Baggiolini, and B. Moser Monocyte chemotactic proteins MCP-1, MCP-2, and MCP-3 are major attractants for human CD4+ and CD8+ T lymphocytes FASEB J. 8 1994 1055 1060
23. A.D. Luster, and J.V. Ravetch Genomic characterization of a gamma-interferon-inducible gene (IP-10) and identification of an interferon-inducible hypersensitive site Mol. Cell. Biol. 7 1987 3723 3731
24. C.M. McManus, J.S. Liu, M.T. Hahn, L.L. Hua, C.F. Brosnan, J.W. Berman, and S.C. Lee Differential induction of chemokines in human microglia by type I and II interferons Glia 29 2000 273 280
25. P. Menten, P. Proost, S. Struyf, E. Van Coillie, W. Put, J.P. Lenaerts, R. Conings, J.M. Jaspar, D. De Groote, A. Billiau, G. Opdenakker, and J. Van Damme Differential induction of monocyte chemotactic protein-3 in mononuclear leukocytes and fibroblasts by interferon-alpha/beta and interferon-gamma reveals MCP-3 heterogeneity Eur. J. Immunol. 29 1999 678 685
26. M. Muranaka, and S. Suzuki Studies on safety problem by skin tests using human beta interferon preparation J. Interf. Res. 4 1984 115 122
27. E. Oeda, and K. Shinohara Cutaneous necrosis caused by injection of alpha-interferon in a patient with chronic myelogenous leukemia Am. J. Hematol. 44 1993 213 214
28. I.C. Oliveira, P.J. Sciavolino, T.H. Lee, and J. Vilcek Downregulation of interleukin 8 gene expression in human fibroblasts: unique mechanism of transcriptional inhibition by interferon Proc. Natl. Acad. Sci. U. S. A. 89 1992 9049 9053
29. I.C. Oliveira, N. Mukaida, K. Matsushima, and J. Vilcek Transcriptional inhibition of the interleukin-8 gene by interferon is mediated by the NF-kappa B site Mol. Cell. Biol. 14 1994 5300 5308
30. S.J. Orlow, and A.E. Friedman-Kien Cutaneous ulcerations secondary to interferon alfa therapy of Kaposi's sarcoma Arch. Dermatol. 128 1992 566
31. A.J. Radziwill, and S. Courvoisier Severe necrotising cutaneous lesions complicating treatment with interferon beta-1a J. Neurol. Neurosurg. Psychiatry 67 1999 115
32. W.A. Sheremata, J.R. Taylor, and G.W. Elgart Severe necrotizing cutaneous lesions complicating treatment with interferon beta-1b N. Engl. J. Med. 332 1995 1584
33. S. Struyf, E. Van Collie, L. Paemen, W. Put, J.P. Lenaerts, P. Proost, G. Opdenakker, and J. Van Damme Synergistic induction of MCP-1 and-2 by IL-1beta and interferons in fibroblasts and epithelial cells J. Leukoc. Biol. 63 1998 364 372
34. D.D. Taub, A.R. Lloyd, K. Conlon, J.M. Wang, J.R. Ortaldo, A. Harada, K. Matsushima, D.J. Kelvin, and J.J. Oppenheim Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells J. Exp. Med. 177 1993 1809 1814
35. D.D. Taub, P. Proost, W.J. Murphy, M. Anver, D.L. Longo, J. Van Damme, and J.J. Oppenheim Monocyte chemotactic protein-1 (MCP-1), -2, and -3 are chemotactic for human T lymphocytes J. Clin. Invest. 95 1995 1370 1376
36. D.D. Taub, D.L. Longo, and W.J. Murphy Human interferon-inducible protein-10 induces mononuclear cell infiltration in mice and promotes the migration of human T lymphocytes into the peripheral tissues and human peripheral blood lymphocytes-SCID mice Blood 87 1996 1423 1431
37. E.U. Walther, and R. Hohlfeld Multiple sclerosis: side effects of interferon beta therapy and their management Neurology 53 1999 1622 1627
38. G.F. Webster, R.L. Knobler, F.D. Lublin, E.M. Kramer, and L.R. Hochman Cutaneous ulcerations and pustular psoriasis flare caused by recombinant interferon beta injections in patients with multiple sclerosis J. Am. Acad. Dermatol. 34 1996 365 367
39. Z.H. Zhou, P. Chaturvedi, Y.L. Han, S. Aras, Y.S. Li, P.E. Kolattukudy, D. Ping, J.M. Boss, and R.M. Ransohoff IFN-gamma induction of the human monocyte chemoattractant protein (hMCP)-1 gene in astrocytoma cells: functional interaction between an IFN-gamma-activated site and a GC-rich element J. Immunol. 160 1998 3908 3916
40. V.R. Ziegler, B. Kranke, P. Soyer, and W. Aberer Extensive cutaneous-subcutaneous infiltration as a side-effect of interferon-beta injection Hautarzt 49 1998 310 312