Cleavage of disulfide-linked fetuin-bisphosphonate conjugates with three physiological thiols

Biomacromolecules

Volumn 6, Issue 5, 2005, Pages 2800-2808

  Zhang, Sufeng ^a   Wright, Jennifer E I ^a   Bansal, Geeti ^a   Cho, Philip ^a   Uludag, Hasan ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AGENTS; BINDING ENERGY; BIOCHEMISTRY; BIOMATERIALS; BIOSYNTHESIS; BONE; HYDROXYAPATITE; PHOSPHATE MINERALS; PHYSIOLOGY; PROTEINS; SULFUR COMPOUNDS;

BONE AFFINITY; DISULFIDE LINKAGE; FETUIN-BISPHOSPHONATE CONJUGATES; PHYSIOLOGICAL THIOLS;

BIOPOLYMERS;

2 (3 MERCAPTOPROPYLSULFANYL)ETHYL 1,1 BISPHOSPHONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CYSTEINE; DISULFIDE; FETUIN; GLUTATHIONE; HOMOCYSTEINE; HYDROXYAPATITE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BONE DISEASE; BONE MINERAL; DRUG BINDING; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; PRIORITY JOURNAL; PROTEIN SECRETION;

ALPHA-FETOPROTEINS; BIOCOMPATIBLE MATERIALS; BONE DISEASES; CROSS-LINKING REAGENTS; CYSTEINE; DIPHOSPHONATES; DISULFIDES; DITHIONITROBENZOIC ACID; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; GLUTATHIONE; HOMOCYSTEINE; HUMANS; HYDROXYAPATITES; MODELS, CHEMICAL; SULFHYDRYL COMPOUNDS; TIME FACTORS; TRINITROBENZENESULFONIC ACID;

EID: 25844459938     PISSN: 15257797     EISSN: None     Source Type: Journal    
DOI: 10.1021/bm050273s     Document Type: Article

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