Pumpin' FU (or, avoiding that oral fixation)

Clinical Advances in Hematology and Oncology

Volumn 3, Issue 5, 2005, Pages 405-406

  Hochster, Howard S ^a  

^a NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; CAPECITABINE; FLUOROURACIL; FOLINIC ACID; OXALIPLATIN; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIMETABOLITE; DEOXYCYTIDINE; DRUG DERIVATIVE; FOLFOX PROTOCOL; PLATINUM COMPLEX;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER ADJUVANT THERAPY; CANCER MORTALITY; CLINICAL TRIAL; COLORECTAL CANCER; DEHYDRATION; DIARRHEA; DRUG COST; DRUG EFFICACY; DRUG PREFERENCE; DRUG SAFETY; DRUG TOLERABILITY; EVIDENCE BASED MEDICINE; FEBRILE NEUTROPENIA; HAND FOOT SYNDROME; HUMAN; MUCOSA INFLAMMATION; NEUTROPENIA; PATIENT ATTITUDE; RISK REDUCTION; VOMITING; COLORECTAL TUMOR; CONTROLLED CLINICAL TRIAL; ECONOMICS; NOTE; RANDOMIZED CONTROLLED TRIAL; STANDARD;

ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; COLORECTAL NEOPLASMS; DEOXYCYTIDINE; FLUOROURACIL; HUMANS; LEUCOVORIN; ORGANOPLATINUM COMPOUNDS; RANDOMIZED CONTROLLED TRIALS;

EID: 25844439999     PISSN: 15430790     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. de Gramont A, Figer M, Seymour, M, et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorecral cancer. J Clin Oncol. 2000;18:2938-2947.
2. André T, Boni C, Mounedji-Boudiaf L, et al, and the Multicenter International Study of Oxaliplatin/5-Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon Cancer (MOSAIC) Investigators. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med. 2004;350:2343-2351.
3. Rothenberg ML, Oza AM, Bigelow RH, et al. Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracil-leucovorin: interim Results of a Phase III Trial. J Clin Oncol. 2003;21:2059-2069.
4. A de Gramont, J. Bosset, C Milan, et al. Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: a French intergroup study. J Clin Oncol. 1997;15:808-815.
5. Leichman CG, Benedetti J, Hochster H, Zalupski M, Benson A, Macdonald J. Phase III trial of protractediInfusion (PI) vs intermittent high-dose infusion (HDI) 5-fluorouracil (5-FU) in patients (PTS) with disseminated colorectal cancer (DCRC). A Southwest Oncology Group (SWOG) and Eastern Cooperative Oncology Group (ECOG) study. Proc Am Soc Clin Oncol. 2001;21. Abstract 497.
6. Ratain MJ. Dear doctor: we really are not sure what dose of capecitabine you should prescribe for your patient. J Clin Oncol. 2002;20:1434-1435.
7. Hochster HS, Welles L, Hart R, et al. Bevacizumab (B) with oxaliplatin (O)-based chemotherapy in the first-line therapy of metastatic colorectal cancer (mCRC): preliminary results of the randomized "TREE-2" trial. Proc Am Soc Clin Oncol GI Symposium. 2005; Abstract 241.