Ten polymorphisms of estrogen-metabolizing genes and a family history of colon cancer - An association study of multiple gene-gene interactions

Journal of the Society for Gynecologic Investigation

Volumn 12, Issue 7, 2005, Pages

  Huber, Ambros ^b   Bentz, Eva Katrin ^b   Schneeberger, Christian ^b   Huber, Johannes C ^b   Hefler, Lukas ^b   Tempfer, Clemens ^a  

^a UNIV KLIN FÜR FRAUENHEILKUNDE   (Austria)

^b NONE

Author keywords

Estrogen; Gene; Microarray; Polymorphism; Risk factor

Indexed keywords

AROMATASE; CATECHOL METHYLTRANSFERASE; CYTOCHROME P450 17; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GUANINE; METHIONINE; TESTOSTERONE 17BETA DEHYDROGENASE; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; CANCER FAMILY; CANCER RISK; COLON CARCINOMA; CONTROLLED STUDY; DNA MICROARRAY; ESTROGEN METABOLISM; ESTROGEN THERAPY; FAMILY HISTORY; FEMALE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MULTIGENE FAMILY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; CASE-CONTROL STUDIES; COLONIC NEOPLASMS; ESTROGENS; FEMALE; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEDIGREE; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, ESTROGEN; RISK FACTORS;

EID: 25844439337     PISSN: 10715576     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsgi.2005.07.003     Document Type: Article

References (13)

1. American Cancer Society Cancer facts and figures 2003 American Cancer Society Atlanta, GA
2. A. de la Chapelle Genetic predisposition to colorectal cancer Nat Rev Cancer 4 2004 769 780
3. Z. Gong, D. Xie, Z. Deng The PPAR γ Pro12Ala polymorphism and risk for incident sporadic colorectal adenomas Carcinogenesis 26 3 2005 579 585
4. Tamer L, Ercan B, Ates NA, et al. N-acetyltransferase 2 gene polymorphism in patients with colorectal carcinoma. Cell Biochem Funct Dec 22, 2004 [Epub ahead of print].
5. M.L. Slattery, M. Murtaugh, B. Caan, K.N. Ma, R. Wolff, W. Samowitz Associations between BMI, energy intake, energy expenditure, VDR genotype and colon and rectal cancers (United States) Cancer Causes Control 15 2004 863 872
6. G.L. Anderson, M. Limacher, A.R. Assaf Women's Health Initiative Steering Committee. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy The Women's Health Initiative randomized controlled trial JAMA 291 2004 1701 1712
7. J.E. Rossouw, G.L. Anderson, R.L. Prentice Risks and benefits of estrogen plus progestin in healthy postmenopausal women Principal results From the Women's Health Initiative randomized controlled trial JAMA 288 2002 321 333
8. B.J. Caan, A.O. Coates, M.L. Slattery Body size and the risk of colon cancer in a large case-control study Int J Obes Relat Metab Disord 22 1998 178 184
9. L. Hou, B.T. Ji, A. Blair, Q. Dai, Y.T. Gao, W.H. Chow Commuting physical activity and risk of colon cancer in Shanghai, China Am J Epidemiol 160 2004 860 867
10. C. Tempfer, C. Schneeberger, J.C. Huber Applications of polymorphisms and pharmacogenomics in obstetrics and gynecology Pharmacogenomics 5 2004 57 65
11. M. Huber, A. Mundlein, E. Dornstauder Accessing single nucleotide polymorphisms in genomic DNA by direct multiplex polymerase chain reaction amplification on oligonucleotide microarrays Anal Biochem 303 2002 25 33
12. M.J. Khoury, L.L. McCabe, E.R. McCabe Population screening in the age of genomic medicine N Engl J Med 348 2003 50 58
13. J. Brockmoller, I. Cascorbi, S. Henning, C. Meisel, I. Roots Molecular genetics of cancer susceptibility Pharmacology 61 2000 212 227