Antipsychotic polypharmacy: Do benefits justify the risks? [1]

Annals of Pharmacotherapy

Volumn 39, Issue 10, 2005, Pages 1759-1760

  Tapp, Andre M ^a   Wood, Amanda Ernst ^a   Kilzieh, Nael ^a   Kennedy, Annette ^b   Raskind, Murray A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Seattle Children's Hospital and Research Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; HALOPERIDOL; LOXAPINE; NEUROLEPTIC AGENT; OLANZAPINE; QUETIAPINE; RISPERIDONE; TIOTIXENE;

EXTRAPYRAMIDAL SYMPTOM; EXTRAPYRAMIDAL SYMPTOM SCALE; HUMAN; LETTER; PARANOID SCHIZOPHRENIA; POLYPHARMACY; POSITIVE AND NEGATIVE SYNDROME SCALE; PRIORITY JOURNAL; RATING SCALE; RISK BENEFIT ANALYSIS; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA;

ANTIPSYCHOTIC AGENTS; DRUG THERAPY, COMBINATION; HUMANS; PSYCHOTIC DISORDERS; RETROSPECTIVE STUDIES; RISK; SCHIZOPHRENIA;

EID: 25844431653     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1E429     Document Type: Letter

References (5)

1. Meltzer HY, Kostakoglu AE. Combining antipsychotics: is there evidence for efficacy? Psychiatr Times 2000;Sept:25-33.
2. Shiloh R, Zemishlany Z, Aizenberg D, Radwan M, Schwanz B, Dorfman-Etrog P, et al. Sulpiride augmentation in people with schizophrenia partially responsive to clozapine. A double-blind, placebo-controlled study. Br J Psychiatry 1997;171:569-73.
3. Potter WZ, Ko GN, Zhang LD, Van WW. Clozapine in China: a review and preview of US/PRC collaboration. Psychopharmacology 1989; 99(suppl):S87-91.
4. Josiassen RC, Joseph A, Kohegyi E, Stokes S, Dadvand M, Paing WW, et al. Clozapine augmented with risperidone in the treatment of schizophrenia: a randomized, double-blind, placebo-controlled trial. Am J Psychiatry 2005;162:130-6.
5. Anil Yagcioglu AE, Kivircik Akdede BB, Turgut TI, Tumuklu M, Yazici MK, Alptekin KY, et al. A double-blind controlled study of adjunctive treatment with risperidone in schizophrenic patients partially responsive to clozapine: efficacy and safety. J Clin Psychiatry 2005;66:63-72.