Preliminary investigations in vitro optical clearing of rat skin using island damage method for accelerated delivery of index-matching agents

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 5771, Issue , 2005, Pages 344-348

  Gavrilova, A A ^a   Tabatadze, D ^b   Childs, J ^b   Yaroslavsky, I ^b   Altshuler, G ^b   Pravdin, A B ^a   Tuchin, V V ^a  

^a SARATOV STATE UNIVERSITY   (Russian Federation)

^b Palomar Medical Technologies Inc   (United States)

Author keywords

Glucose; Glycerol; Index matching agent; Optical clearing; Stratum corneum; Thermal damage

Indexed keywords

INDEX MATCHING AGENT; OPTICAL CLEARING; STRATUM CORNEUM; THERMAL DAMAGE;

DIAGNOSIS; GLUCOSE; GLYCEROL; REFRACTIVE INDEX; SCATTERING; SKIN;

LIGHT SCATTERING;

EID: 25644460276     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.634858     Document Type: Conference Paper

References (10)

1. Xiangqun Xu and Ruikang K Wang "Synergistic effect of hyperosmotic agents of dimethyl sulfoxide and glycerol on optical clearing of gastric tissue studied with near infrared spectroscopy", Physics in Medicine and Biology. 49, pp. 457-468, 2004.
2. Fabrice Pirot, Yogeshvar N. Kalia, Audra L. Stinchcomb, Garrett Keating, Annette Bunge, and Richard H. Guy "Characterization of the permeability barrier of human skin in vivo", Proc. Natl. Acad. Sci. USA. 94, pp. 1562-1567, 1997.
3. Gracie Vargas, Kin F. Chan, Sharon L Thomsen, and A.J. Welch "Use of osmotically active agents to alter optical properties of tissue: effects on the detected fluorescence signal measured through skin", Lasers in Surgery and Medicine. 29, pp. 213-220, 2001.
4. Jingying Jiang and Ruikang K Wang "Comparing the synergistic effects of oleic acid and dimethyl sulfoxide as vehicles for optical clearing of skin tissue in vitro", Physics in Medicine and Biology. 49, pp. 5283-5294, 2004.
5. Gracie Vargas, Allison Readinger, Susan S. Dozier and A.J. Welch "Morphological Changes in Blood Vessels Produced by Hyperosmotic Agents and Measured by Optical Coherence Tomography", Photochemistry and Photobiology. 77(5), pp. 541-549, 2003.
6. Bakutkin V.V., Maksimova I.L., Semyonova T.N., Tuchin V.V., Kon I.L. "Controlling of optical properties of sciera", Proc SPIE. 2393, pp. 137-141, 1995.
7. Liu H, Beauvoit B, Kimura M, Chance B. "Dependence of tissue optical properties on solute-induced changes in refractive index and osmolarity", J. Biomed Opt., 1, pp. 200-211, 1996.
8. Tuchin V.V., Maksimova I.L., Zimnyakov D.A., Kon I.L., Mavlutov A.K., Mishin A.A. "Light propagation in tissues with controlled optical properties", J. Biomed Opt. 2, pp. 401-417, 1997.
9. Vargas G., Chan E.K., Barton J.K., Rylander H.G., Welch A.J. "Use of an agent to reduce scattering in skin", Lasers Surg. Med 24, pp. 133-141, 1999.
10. Zimnyakov D.A., Tuchin V.V., Mishin A.A., Kon I.L., Serov A.N. "In vivo human sciera structure analysis using tissue optical immersion effect", Proc. SPIE. 2673, pp. 233-242, 1996.