Kremezin (AST-120) delays the progression of diabetic nephropathy in Japanese type 2 diabetic patients

Diabetes Care

Volumn 28, Issue 10, 2005, Pages 2590-

  Shimizu, Hiroyuki ^a   Okada, Shuichi ^a   Shinsuke, Oh I ^a   Mori, Masatomo ^a  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADSORBENT; AST 120; CREATININE; INDICAN;

ARTICLE; ASIAN; CLINICAL TRIAL; CREATININE BLOOD LEVEL; DIABETIC NEPHROPATHY; DRUG EFFECT; HUMAN; JAPANESE; NON INSULIN DEPENDENT DIABETES MELLITUS; RENAL PROTECTION;

CARBON; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; HUMANS; JAPAN; OXIDES; TREATMENT OUTCOME;

EID: 25644458631     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.28.10.2590     Document Type: Article

References (3)

1. Aoyama I, Niwa T: An oral adsorbent ameliorates renal overload of indoxyl sulfate and progression of renal failure in diabetic rats. Am J Kidney Dis 37 (Suppl. 2):S7-S12, 2001
2. Schulman G, Agarwal R, Acharya M, Berl T, Blumenthal S, Kopyt N: KREMEZIN (AST-120) reduces indoxyl sulfate (IS), a profibrotic compound in patients with chronic kidney disease (CKD): results from a multicenter, randomized, double-blind study (Abstract). In American Society of Nephrology (ASN) 37th Annual Meeting and Scientific Exposition, St. Louis, MO. Washington, DC, ASN, 2004, p. 162
3. Salazar D, Galitz L, Vargas R, Maner J-F: Effect of the oral adsorbent AST-120 on serum creatinine and other renal markers in patients with chronic kidney disease (Abstract). In 6th International Meeting of the International Federation of Kidney Foundations, Dublin, Ireland, 2005. New York, IFKF, 2005