Effect of gefarnate on acute gastric mucosal lesion progression in rats treated with compound 48/80, a mast cell degranulator, in comparison with that of teprenone

Biological and Pharmaceutical Bulletin

Volumn 28, Issue 8, 2005, Pages 1424-1430

  Ohta, Yoshiji ^a   Kobayashi, Takashi ^a   Imai, Yoichiro ^b   Inui, Kazuo ^a   Yoshino, Junji ^a   Nakazawa, Saburo ^b  

^a FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b FUJITA HEALTH UNIVERSITY   (Japan)

Author keywords

Compound 48 80; Gastric mucosal lesion (rat); Gastric mucus; Gefarnate; Neutrophil infiltration; Oxidative stress

Indexed keywords

ANTIULCER AGENT; COMPOUND 48-80; GEFARNATE; HEXOSAMINE; HISTAMINE; LIPID; MAST CELL DEGRANULATING PEPTIDE; MYELOPEROXIDASE; SEROTONIN; TEPRENONE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; XANTHINE OXIDASE;

ADHESION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG STRUCTURE; EXAMINATION; HISTAMINE BLOOD LEVEL; LIPID PEROXIDATION; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; PROTEIN CONTENT; RAT; SEROTONIN BLOOD LEVEL; STOMACH BLOOD FLOW; STOMACH MUCOSA LESION;

ANIMALS; ANTI-ULCER AGENTS; CELL DEGRANULATION; DITERPENES; GASTRIC MUCOSA; GEFARNATE; HEXOSAMINES; HISTAMINE; MALE; MAST CELLS; P-METHOXY-N-METHYLPHENETHYLAMINE; PEROXIDASE; RATS; RATS, WISTAR; REGIONAL BLOOD FLOW; SEROTONIN; THIOBARBITURIC ACID REACTIVE SUBSTANCES; XANTHINE OXIDASE;

EID: 25644453378     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.28.1424     Document Type: Article

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