Two aspects of impaired consciousness in Alzheimer's disease

Progress in Brain Research

Volumn 150, Issue , 2005, Pages 287-298

  Salmon, Eric ^a   Ruby, Perrine ^a   Perani, Daniela ^b   Kalbe, Elke ^c   Laureys, Steven ^a   Adam, Stéphane ^a   Collette, Fabienne ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^c MAX PLANCK INSTITUTE FOR NEUROLOGICAL RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ANOSOGNOSIA; ASSOCIATION CORTEX; BRAIN METABOLISM; CLINICAL EXAMINATION; CLINICAL FEATURE; COGNITION; CONSCIOUSNESS DISORDER; FRONTAL CORTEX; HUMAN; LIMBIC SYSTEM; PARIETAL LOBE; PRIORITY JOURNAL; REVIEW;

AGNOSIA; ALZHEIMER DISEASE; BEHAVIOR; BRAIN; COGNITION DISORDERS; CONSCIOUSNESS; HUMANS;

EID: 25644445126     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(05)50021-9     Document Type: Review

References (94)

1. Adam, S., Van der Linden, M., Collette, F., Lemauvais, L. and Salmon, E. (2005). Further exploration of controlled and automatic memory processes in early Alzheimer's disease. Neuropsychology (in press).
2. S.K. Agnew, and R.G. Morris The heterogeneity of anosognosia for memory impairment in Alzheimer's disease: a review of the literature and a proposed model Aging Ment. Health 2 1998 7 19
3. H. Amieva, I. Rouch-Leroyer, C. Fabrigoule, and J.F. Dartigues Deterioration of controlled processes in the preclinical phase of dementia: a confirmatory analysis Dement. Geriatr. Cogn. Disord. 11 2000 46 52
4. APA Diagnostic and Statistical Manual of Mental Disorders 3rd ed. 1987 American Psychiatric Association Washington, DC
5. APA Diagnostic and Statistical Manual of Mental Disorders 4th ed. 1994 American Psychiatric Association Washington, DC
6. N.P. Azari, S.I. Rapoport, C.L. Grady, M.B. Schapiro, J.A. Salerno, and A. Gonzalez-Aviles Patterns of interregional correlations of cerebral glucose metabolism rates in patients with dementia of the Alzheimer type Neurodegeneration 1 1992 101 111
7. B.J. Baars, T.Z. Ramsoy, and S. Laureys Brain conscious experience and the observing self Trends Neurosci. 26 2003 671 675
8. A. Baddeley Working memory Science 255 1992 556 559
9. O. Blanke, S. Ortigue, T. Landis, and M. Seeck Stimulating illusory own-body perceptions Nature 419 2002 269 270
10. N. Breen, D. Caine, and M. Coltheart Mirrored-self misidentification: two cases of focal onset dementia Neurocase 7 2001 239 254
11. F. Collette, E. Salmon, M. Van der Linden, C. Chicherio, S. Belleville, and C. Degueldre Regional brain activity during tasks devoted to the central executive of working memory Brain Res. Cogn. Brain Res. 7 1999 411 417
12. F. Collette, M. Van der Linden, S. Bechet, and E. Salmon Phonological loop and central executive functioning in Alzheimer's disease Neuropsychologia 37 1999 905 918
13. F. Collette, M. Van der Linden, G. Delrue, and E. Salmon Frontal hypometabolism does not explain inhibitory dysfunction in Alzheimer disease Alzheimer Dis. Assoc. Disord. 16 2002 228 238
14. F. Collette, M. Van der Linden, A.C. Juillerat, and T. Meulemans A cognitive neuropsychological approach to Alzheimer's disease R. Mulligan M. Van der Linden A.C. Juillerat Clinical Management of Early Alzheimer's Disease 2003 Erlbaum Mahwah 35 73
15. F. Collette, M. Van der Linden, and E. Salmon Executive dysfunction in Alzheimer's disease Cortex 35 1999 57 72
16. J.L. Cummings, M. Mega, K. Gray, S. Rosenberg-Thompson, D.A. Carusi, and J. Gornbein The Neuropsychiatric inventory: comprehensive assessment of psychopathology in dementia Neurology 44 1994 2308 2314
17. J.L. Cummings, W. Ross, J. Absher, J. Gornbein, and L. Hadjiaghai Depressive symptoms in Alzheimer disease: assessment and determinants Alzheimer Dis. Assoc. Disord. 9 1995 87 93
18. T. Curran, and D.L. Hintzman Violations of the independence assumption in process dissociation J. Exp. Psychol. Learn Mem. Cogn. 21 1995 531 547
19. G. Dalla Barba, V. Parlato, A. Iavarone, and F. Boller Anosognosia, intrusions and 'frontal' functions in Alzheimer's disease and depression Neuropsychologia 33 1995 247 259
20. S. Dehaene, and L. Naccache Towards a cognitive neuroscience of consciousness: basic evidence and a workspace framework Cognition 79 2001 1 37
21. C. Derouesne, S. Thibault, S. Lagha-Pierucci, V. Baudouin-Madec, D. Ancri, and L. Lacomblez Decreased awareness of cognitive deficits in patients with mild dementia of the Alzheimer type Int. J. Geriatr. Psychiatry 14 1999 1019 1030
22. C. Fabrigoule, I. Rouch, A. Taberly, L. Letenneur, D. Commenges, and J.M. Mazaux Cognitive process in preclinical phase of dementia Brain 121 Pt 1 1998 135 141
23. D.A. Fleischman, and J.D. Gabrieli Repetition priming in normal aging and Alzheimer's disease: a review of findings and theories Psychol. Aging 13 1998 88 119
24. P.C. Fletcher, T. Shallice, and R.J. Dolan The functional roles of prefrontal cortex in episodic memory I. Encoding. Brain 121 Pt 7 1998 1239 1248
25. M.F. Folstein, S.E. Folstein, and P.R. McHugh "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician J. Psychiatr. Res. 12 1975 189 198
26. R. Gil, E.M. Arroyo-Anllo, P. Ingrand, M. Gil, J.P. Neau, and C. Ornon Self-consciousness and Alzheimer's disease Acta Neurol. Scand. 104 2001 296 300
27. J.D. Greene, J.R. Hodges, and A.D. Baddeley Autobiographical memory and executive function in early dementia of Alzheimer type Neuropsychologia 33 1995 1647 1670
28. D.A. Gusnard, E. Akbudak, G.L. Shulman, and M.E. Raichle Medial prefrontal cortex and self-referential mental activity: relation to a default mode of brain function Proc. Natl. Acad. Sci. USA 98 2001 4259 4264
29. D.G. Harwood, D.L. Sultzer, and M.V. Wheatley Impaired insight in Alzheimer disease: association with cognitive deficits, psychiatric symptoms, and behavioral disturbances Neuropsychiatry Neuropsychol. Behav. Neurol. 13 2000 83 88
30. R.N. Henson, M.D. Rugg, T. Shallice, O. Josephs, and R.J. Dolan Recollection and familiarity in recognition memory: an event-related functional magnetic resonance imaging study J. Neurosci. 19 1999 3962 3972
31. K. Herholz, E. Salmon, D. Perani, J.C. Baron, V. Holthoff, and L. Frolich Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET Neuroimage 17 2002 302 316
32. B.T. Hyman, G.W. Van Horsen, A.R. Damasio, and C.L. Barnes Alzheimer's disease: cell-specific pathology isolates the hippocampal formation Science 225 1984 1168 1170
33. L.L. Jacoby, D.S. Lindsay, and J.P. Toth Unconscious influences revealed. Attention, awareness, and control Am. Psychol. 47 1992 802 809
34. S.C. Johnson, L.C. Baxter, L.S. Wilder, J.G. Pipe, J.E. Heiserman, and G.P. Prigatano Neural correlates of self-reflection Brain 125 2002 1808 1814
35. A.F. Jorm Controlled and automatic information processing in senile dementia: a review Psychol. Med. 16 1986 77 88
36. E. Kalbe, E. Salmon, D. Perani, V. Holthoff, S. Sorbi, and A. Elsner Anosognosia in very mild Alzheimer's disease but not in mild cognitive impairment Dement. Geriatr. Cogn. Disord. 19 2005 349 356
37. H. Kazui, M. Hashimoto, N. Hirono, and E. Mori Nature of personal semantic memory: evidence from Alzheimer's disease Neuropsychologia 41 2003 981 988
38. W.M. Kelley, C.N. Macrae, C.L. Wyland, S. Caglar, S. Inati, and T.F. Heatherton Finding the self? An event-related fMRI study J. Cogn. Neurosci. 14 2002 785 794
39. S.B. Klein, L. Cosmides, and K.A. Costabile Preserved knowledge of self in a case of Alzheimer's dementia Soc. Cognition 21 2003 157 165
40. S.B. Klein, K. Rozendal, and L. Cosmides A social-cognitive neuroscience analysis of the self Social Cognition. 20 2002 105 135
41. R.G. Knight Controlled and automatic memory process in Alzheimer's disease Cortex 34 1998 427 435
42. M. Koivisto, R. Portin, A. Seinela, and J. Rinne Automatic influences of memory in Alzheimer's disease Cortex 34 1998 209 219
43. S. Kotler-Cope, and C.J. Camp Anosognosia in Alzheimer disease Alzheimer Dis. Assoc. Disord. 9 1995 52 56
44. F. Lekeu, M. Van der Linden, C. Chicherio, F. Collette, C. Degueldre, and G. Franck Brain correlates of performance in a free/cued recall task with semantic encoding in Alzheimer disease Alzheimer Dis. Assoc. Disord. 17 2003 35 45
45. F. Lekeu, M. Van der Linden, C. Degueldre, C. Lemaire, A. Luxen, and G. Franck Effects of Alzheimer's disease on the recognition of novel versus familiar words: neuropsychological and clinico-metabolic data Neuropsychology 17 2003 143 154
46. F. Lekeu, V. Wojtasik, M. Van der Linden, and E. Salmon Training early Alzheimer patients to use a mobile phone Acta Neurol. Belg. 102 2002 114 121
47. A.F. Leuchter, T.F. Newton, I.A. Cook, D.O. Walter, S. Rosenberg-Thompson, and P.A. Lachenbruch Changes in brain functional connectivity in Alzheimer-type and multi-infarct dementia Brain 115 Pt 5 1992 1543 1561
48. D. Leys, M. Steinling, H. Petit, J.L. Salomez, Y. Gaudet, and E. Ovelacq [Alzheimer's disease: study by single photon emission tomography (Hm PAO Tc99 m)] Rev. Neurol. 145 1989 443 450
49. O.L. Lopez, J.T. Becker, D. Somsak, M.A. Dew, and S.T. DeKosky Awareness of cognitive deficits and anosognosia in probable Alzheimer's disease Eur. Neurol. 34 1994 277 282
50. H.C. Lou, B. Luber, M. Crupain, J.P. Keenan, M. Nowak, and T.W. Kjaer Parietal cortex and representation of the mental Self Proc. Natl. Acad. Sci. USA 101 2004 6827 6832
51. E.A. Maguire, C.D. Frith, and R.G. Morris The functional neuroanatomy of comprehension and memory: the importance of prior knowledge Brain 122 Pt 10 1999 1839 1850
52. E.A. Maguire, and C.J. Mummery Differential modulation of a common memory retrieval network revealed by positron emission tomography Hippocampus 9 1999 54 61
53. K.D. McDaniel, S.D. Edland, and A. Heyman Relationship between level of insight and severity of dementia in Alzheimer disease. CERAD Clinical Investigators. Consortium to Establish a Registry for Alzheimer's Disease Alzheimer Dis. Assoc. Disord. 9 1995 101 104
54. S.M. McGlynn, and D.L. Schacter Unawareness of deficits in neuropsychological syndromes J. Clin. Exp. Neuropsychol. 11 1989 143 205
55. N. Meiran, and M. Jelicic Implicit memory in alzheimer's disease: a meta-analysis Neuropsychology 9 1995 291 303
56. A. Michon, B. Deweer, B. Pillon, Y. Agid, and B. Dubois Relation of anosognosia to frontal lobe dysfunction in Alzheimer's disease J. Neurol. Neurosurg. Psychiatry 57 1994 805 809
57. R. Migliorelli, A. Teson, L. Sabe, G. Petracca, M. Petracchi, and R. Leiguarda Anosognosia in Alzheimer's disease: a study of associated factors J. Neuropsychiatry Clin. Neurosci. 7 1995 338 344
58. R. Migliorelli, A. Teson, L. Sabe, M. Petracchi, R. Leiguarda, and S.E. Starkstein Prevalence and correlates of dysthymia and major depression among patients with Alzheimer's disease Am. J. Psychiatry 152 1995 37 44
59. S. Minoshima, N.L. Foster, and D.E. Kuhl Posterior cingulate cortex in Alzheimer's disease Lancet 344 1994 895
60. R.G. Morris Working memory in Alzheimer-type dementia Neuropsychology 8 1994 544 554
61. D. Neary, J.S. Snowden, L. Gustafson, U. Passant, D. Stuss, and S. Black Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria Neurology 51 1998 1546 1554
62. B.R. Ott, G. Lafleche, W.M. Whelihan, G.W. Buongiorno, M.S. Albert, and B.S. Fogel Impaired awareness of deficits in Alzheimer disease Alzheimer Dis. Assoc. Disord. 10 1996 68 76
63. R.C. Pearson, M.M. Esiri, R.W. Hiorns, G.K. Wilcock, and T.P. Powell Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease Proc. Natl. Acad. Sci. USA 82 1985 4531 4534
64. P. Peigneux, E. Salmon, G. Garraux, S. Laureys, S. Willems, and K. Dujardin Neural and cognitive bases of upper limb apraxia in corticobasal degeneration Neurology 57 2001 1259 1268
65. M. Petrides, B. Alivisatos, E. Meyer, and A.C. Evans Functional activation of the human frontal cortex during the performance of verbal working memory tasks Proc. Natl. Acad. Sci. USA 90 1993 878 882
66. P. Piolino, B. Desgranges, S. Belliard, V. Matuszewski, C. Lalevee, and V. De la Sayette Autobiographical memory and autonoetic consciousness: triple dissociation in neurodegenerative diseases Brain 126 2003 2203 2219
67. B.R. Reed, W.J. Jagust, and L. Coulter Anosognosia in Alzheimer's disease: relationships to depression cognitive function and cerebral perfusion J. Clin. Exp. Neuropsychol. 15 1993 231 244
68. P. Ruby, and J. Decety Effect of subjective perspective taking during simulation of action: a PET investigation of agency Nat. Neurosci. 4 2001 546 550
69. P. Ruby, and J. Decety What you believe versus what you think they believe: a neuroimaging study of conceptual perspective-taking Eur. J. Neurosci. 17 2003 2475 2480
70. P. Ruby, and J. Decety How Would You Feel versus How Do You Think She Would Feel? A Neuroimaging Study of Perspective-Taking with Social Emotions J. Cogn. Neurosci. 16 2004 988 999
71. D.P. Salmon Disorders of memory in Alzheimer's disease F. Boller J. Grafman Handbook of Neuropsychology (2nd ed.) 2000 Elsevier Science B.V. Amsterdam 155 195
72. E. Salmon Physiology of human memory explored by functional imaging P.P. De Deyn E. Thiery R. D'Hogge Memory. Basic Concepts, Disorders and Treatment 2003 Acco Leuven 321 336
73. E. Salmon, F. Collette, C. Degueldre, C. Lemaire, and G. Franck Voxel-based analysis of confounding effects of age and dementia severity on cerebral metabolism in Alzheimer's disease Hum. Brain Mapping 10 2000 39 48
74. E. Salmon, F. Collette, M. Van der Linden, and G. Franck Increased demand on executive processes decreases activity in posteromedial regions Neuroimage 9 1999 S340
75. E. Salmon, G. Garraux, X. Delbeuck, F. Collette, E. Kalbe, and G. Zuendorf Predominant ventromedial frontopolar metabolic impairment in frontotemporal dementia Neuroimage 20 2003 435 440
76. E. Salmon, S. Lespagnard, P. Marique, K. Herhol, D. Perani, and V. Holthoff Cerebral metabolic correlates of four dementia scales in Alzheimer's disease J. Neurol. 252 2005 283 290
77. Salmon, E., Perani, D., Herholz, K., Marique, P., Kalbe, E., Holthoff, V., Delbeucq, X., Beuthien-Bauman, B., Pelati, O., Lespagnard, S., Collette, F. and Garraux, G. (2004). Multiple regional cerebral account for unawareness of cognitive impairment in AD. HBM Abstract, Budapest.
78. T.A. Salthouse, and J.T. Becker Independent effects of Alzheimer's disease on neuropsychological functioning Neuropsychology 12 1998 242 252
79. S. Sevush Relationship between denial of memory deficit and dementia severity in Alzheimer disease Neuropsychiatry Neuropsychol. Behav. Neurol. 12 1999 88 94
80. S. Sevush, and N. Leve Denial of memory deficit in Alzheimer's disease Am. J. Psychiatry 150 1993 748 751
81. L.R. Squire Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans Psychol. Rev. 99 1992 195 231
82. S.E. Starkstein, S. Vazquez, R. Migliorelli, A. Teson, L. Sabe, and R. Leiguarda A single-photon emission computed tomographic study of anosognosia in Alzheimer's disease Arch. Neurol. 52 1995 415 420
83. M.H. Tabert, S.M. Albert, L. Borukhova-Milov, Y. Camacho, G. Pelton, and X. Liu Functional deficits in patients with mild cognitive impairment: prediction of AD Neurology 58 2002 758 764
84. Tulving, E. (1993). Self-knowledge of an amnesic individual is represented abstractly. In: Srull, T.Kw., R.S., (Ed.) Advances in Social Cognition. Vol. 5. Erlbaum, Hillsdale, NJ, pp. 147-156.
85. E. Tulving Episodic memory: from mind to brain Annu. Rev. Psychol. 53 2002 1 25
86. C.J. Vaidya, J.D. Gabrieli, J.B. Demb, M.M. Keane, and L.C. Wetzel Impaired priming on the general knowledge task in amnesia Neuropsychology 10 1996 529 537
87. A. Venneri, and M.F. Shanks Belief and awareness: reflections on a case of persistent anosognosia Neuropsychologia 42 2004 230 238
88. K. Vogeley, P. Bussfeld, A. Newen, S. Herrmann, F. Happe, and P. Falkai Mind reading: neural mechanisms of theory of mind and self-perspective Neuroimage 14 2001 170 181
89. K. Vogeley, M. May, A. Ritzl, P. Falkai, K. Zilles, and G.R. Fink Neural correlates of first-person perspective as one constituent of human self-consciousness J. Cogn. Neurosci. 16 2004 817 827
90. D.R. Weinberger A connectionist approach to the prefrontal cortex J. Neuropsychiatry Clin. Neurosci. 5 1993 241 253
91. M.A. Wheeler, D.T. Stuss, and E. Tulving Toward a theory of episodic memory: the frontal lobes and autonoetic consciousness Psychol. Bull. 121 1997 331 354
92. B. Wicker, P. Ruby, J.P. Royet, and P. Fonlupt A relation between rest and the self in the brain? Brain Res. Brain Res. Rev. 43 2003 224 230
93. A.P. Yonelinas, and L.L. Jacoby Dissociating automatic and controlled processes in a memory-search task: beyond implicit memory Psychol. Res. 57 1995 156 165
94. O. Zanetti, B. Vallotti, G.B. Frisoni, C. Geroldi, A. Bianchetti, and P. Pasqualetti Insight in dementia: when does it occur? Evidence for a nonlinear relationship between insight and cognitive status J. Gerontol. B Psychol. Sci. Soc. Sci. 54 1999 100 106