Effects of various selective phosphodiesterase inhibitors on carbachol-induced contraction and cyclic nucleotide contents in the guinea pig gall bladder

Journal of Veterinary Medical Science

Volumn 67, Issue 7, 2005, Pages 659-665

  Kaneda, Takeharu ^a   Watanabe, Akitoshi ^a   Shimizu, Kazumasa ^a   Urakawa, Norimoto ^a   Nakajyo, Shinjiro ^a  

^a NIPPON VETERINARY AND LIFE SCIENCE UNIVERSITY   (Japan)

Author keywords

cAMP; cGMP; Gall bladder; PDE inhibitor

Indexed keywords

CAVIA PORCELLUS; TAENIA; TENIA;

4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; 9 (2 HYDROXY 3 NONYL)ADENINE; 9-(2-HYDROXY-3-NONYL)ADENINE; ADENINE; CARBACHOL; CYCLIC AMP; CYCLIC GMP; CYCLIC NUCLEOTIDE; DRUG DERIVATIVE; MILRINONE; PHOSPHODIESTERASE INHIBITOR; PURINE DERIVATIVE; VINCA ALKALOID; VINPOCETINE; ZAPRINAST;

ANIMAL; ARTICLE; COMPARATIVE STUDY; DRUG EFFECT; GALLBLADDER; GUINEA PIG; MALE; METABOLISM; MUSCLE CONTRACTION; PHYSIOLOGY;

4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDINONE; ADENINE; ANIMALS; CARBACHOL; CYCLIC AMP; CYCLIC GMP; GALLBLADDER; GUINEA PIGS; MALE; MILRINONE; MUSCLE CONTRACTION; NUCLEOTIDES, CYCLIC; PHOSPHODIESTERASE INHIBITORS; PURINONES; VINCA ALKALOIDS;

EID: 25644432815     PISSN: 09167250     EISSN: None     Source Type: Journal    
DOI: 10.1292/jvms.67.659     Document Type: Article

References (23)

1. Ahn, H.S., Crim, W., Romano, M., Sybertz, E. and Pitts, B. 1989. Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta. Biochem. Pharmacol. 38: 3331-3339.
2. Barnette, M.S., Manning, C.D., Price, W.J. and Barone, F.B. 1993. Initial biochemical and functional characterization of cyclic nucleotide phosphodiesterase isozymes in canine colonic smooth muscle. J. Pharmacol. Exp. Ther. 264: 801-812.
3. Beavo, J.A. 1995. Cyclic nucleotide phosphodiesterase : functional implications of multiple isoforms. Physiol. Rev. 75: 725-748.
4. Beavo, J.A. and Reifsnyder, D.H. 1990. Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors. Trend. Pharmacol. Sci. 11: 150-155.
5. Diamond, J. 1978. Role of cyclic nucleotides in control of smooth muscle contraction. pp. 327-340. In: Advances in Cyclic Nucleotide Research, vol. 9 (George, W.J. and Ignarro, L.J. eds.), Raven Press, New York.
6. Fawcett, L., Baxendale, R., Stacey, P., McGrother, C., Harrow, I., Soderling, S.H. and Beavo, J.A. 2000. Molecular cloning and characterization of distinct human phsphodiesterase gene family: PDE11A. Proc. Natl. Acard. Sci. U.S.A. 97: 3702-3707.
7. Hagiwara, M., Endo, T. and Hidaka, H. 1984. Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle. Biochem. Pharmacol. 33: 453-457.
8. Harris, A.L., Cornell, M.J., Ferguson, E.W., Wallace, A.M., Gordon, R.J., Pagani, E.D. and Silver, P.J. 1989. Role of low Km cyclic AMP phosphodiesterase inhibition in tracheal relaxation and bronchodilation in the guinea pig. J. Pharmacol. Exp. Ther. 251: 199-206.
9. Haynes, J. Jr., Killiea, D.W., Peterson, P.D. and Thompson, J. 1996. Erthro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic-3′,5′-guanosine monophosphate-stimulated phosphodiesterase to reverse hypoxic pulmonary vasoconstriction in the perfused rat lung. J. Pharmacol. Exp. Ther. 276: 752-756.
10. Kaneda, T., Shimizu, K., Nakajyo, S. and Urakawa, N. 1997. Effects of various selective phosphodiesterase inhibitors on muscle contractility in guinea pig ileal longitudinal smooth muscle. Jpn. J. Pharmacol. 75: 77-85.
11. Kaneda, T., Shimizu, K., Urakawa, N. and Nakajyo, S. 2004. Effects of various selective phosphodiesterase inhibitors on carbachol-induced contraction and cyclic nucleotide contents in guinea pig taenia coli. J. Vet. Med. Sci. 66: 1047-1052.
12. Kaneda, T., Yamamoto, H., Azegami, Y., Shimizu, K., Urakawa, N. and Nakajyo, S. 2003. Lack of cyclic nucleotide regulation of MBCQ-induced relaxation of rat ileal smooth muscle. J. Smooth. Muscle. Res. 39: 47-54.
13. Pauvert, O., Salvail, D., Rousseau, E., Lugnier, C., Marthan, R. and Savineau, J.P. 2002. Characterization of cyclic nucleotide phosphodiesterase isoforms in the media layer of the main pulmonary artery. Biochem. Pharmacol. 63: 1763-1772.
14. Polson, J.B. and Strada, S.J. 1996. Cyclic nucleotide phosphodiesterases and vascular smooth muscle. Annu. Rev. Phramacol. Toxicol. 36: 403-427.
15. Qiu, Y., Kraft, P., Craig, E.C., Liu, X. and Haynes-Johnson, D. 2001. Identification and functional study of phosphodiesterases in rat urinary bladder. Urol. Res. 29: 388-392.
16. Raeburn, D. and Advenier, C. 1995. Isoenzyme-selective cyclic nucleotide phosphodiesterase inhibitors: Effects on airways smooth muscle. Int. J. Biochem. Cell. Biol. 27: 29-37.
17. Rybalkin, S.D., Yan, C., Bornfeldt, K.E. and Beavo J.A. 2003. Cyclic GMP phosphodiesterases and regulation of smooth muscle function. Circ. Res. 93: 280-291.
18. Schoeffer, P., Lugnier, C., Demesy-Waeldele, F. and Stoclet, J.C. 1987. Role of cyclic AMP- and cyclic GMP-phosphodiesterase in the control of cyclic nucleotide levels and smooth muscle tone in rat isolated aorta. A study with selective inhibitors. Biochem. Pharmacol. 36: 3965-3975.
19. Shahid, M., van Amsterdam, R.G.M., de Boer, J., ten Berge, R.E., Nicholson, C.D. and Zaagama, J. 1991. The presence of five cyclic nucleotide phosphodiesterase isoenzyme activities in bovine tracheal smooth muscle and the functional effects of selective inhibitors. Br. J. Pharmacol. 104: 471-477.
20. Souness, J.E., Brazdil, R., Diocee, B.K. and Jordan, R. 1989. Role of selective cyclic GMP phosphodiesterase inhibition in the myorelaxant actions of M & B22,948, MY-5445, vinpocetine and 1-methyl-3-isobutyl-8- (methlammino) xanthine. Br. J. Pharmacol. 98: 725-734.
21. Tomkinson, A. and Raeburn, D. 1996. The effect of isoenzyme-selective PDE inhibitors on methacholine-induced contraction of guinea-pig and rat ileum. Br. J. Pharmacol. 118: 2131-2139.
22. Truss, M.C., Ückert, S., Stief, C.G., Kuczyk, M., Schulz-Knappe, P., Forssmann, W.-G. and Jonas, U. 1996. Effects of various phosphodiesterase- inhibitors, forskolin, and sodium nitroprusside on porcine detrusor smooth muscle tonic responses to muscarinergic stimulation and cyclic nucleotide levels in vitro. Neurourol. Urodyn. 15: 59-70.
23. Yuasa, K., Kotera, J., Fujishige, K., Michibata, H., Sasaki, T. and Omori, K. 2000. Isolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expression. J. Biol. Chem. 275: 31469-31479.