Stereochemical assignment of the C1-C6 fragment of psymberin by synthesis and natural product degradation

Organic Letters

Volumn 7, Issue 19, 2005, Pages 4117-4120

  Green, Michael E ^a   Rech, Jason C ^a   Floreancig, Paul E ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; AMINE; BIOLOGICAL PRODUCT; PEDERIN; PSYMBERIN; PYRAN DERIVATIVE; PYRONE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; GAS CHROMATOGRAPHY; STEREOISOMERISM; SYNTHESIS;

AMIDES; AMINES; BIOLOGICAL PRODUCTS; CHROMATOGRAPHY, GAS; MOLECULAR STRUCTURE; PYRANS; PYRONES; STEREOISOMERISM;

EID: 25444532568     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol051396s     Document Type: Article

References (22)

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13. This reaction provided an approximately 2:1 ratio of diastereomers. No attempt at stereochemical assignment was made.
14. For structural analysis and experimental details, see Supporting Information.
15. The psymberin that was used in these studies was generously provided by Professor Phil Crews and his group at the University of California, Santa Cruz.
16. Relevant fragments result from the loss of a methyl group, the loss of a methyl group and methanol, and the loss of the carbomethoxy group.
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