Effectiveness of clonidine and fentanyl addition to bupivacaine in postoperative patient controlled epidural analgesia;Wirksamkeit von clonidin und fentanyl als zusatz bei der postoperativen patientenkontrollierten epiduralanalgesie mit bupivacain

Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie

Volumn 40, Issue 9, 2005, Pages 521-525

  Topcu, I ^a   Luleci, N ^a   Tekin, S ^a   Kefi, A ^a   Erincler, Tuna ^a  

^a CELAL BAYAR UNIVERSITY   (Turkey)

Author keywords

Clonidine; Epidural analgesia; Fentanyl; Nausea; Postoperative analgesia

Indexed keywords

ANALGESIC AGENT; BUPIVACAINE; CLONIDINE; FENTANYL; LIDOCAINE; THIOPENTAL; VECURONIUM;

ABDOMINAL HYSTERECTOMY; ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG USE; EPIDURAL ANESTHESIA; EVALUATION; FEMALE; HEMODYNAMIC MONITORING; HUMAN; INTRAVENOUS ANESTHESIA; MAJOR CLINICAL STUDY; NAUSEA; OUTCOMES RESEARCH; PAIN ASSESSMENT; PATIENT CONTROLLED ANALGESIA; PATIENT SATISFACTION; POSTOPERATIVE PAIN; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SEDATION; VISUAL ANALOG SCALE;

ADOLESCENT; ADRENERGIC ALPHA-AGONISTS; ADULT; AGED; ANALGESIA, EPIDURAL; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS, OPIOID; ANESTHETICS, LOCAL; BUPIVACAINE; CLONIDINE; FEMALE; FENTANYL; HEMODYNAMIC PROCESSES; HUMANS; HYSTERECTOMY; MIDDLE AGED; PAIN MEASUREMENT; PAIN, POSTOPERATIVE;

EID: 25444530359     PISSN: 09392661     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-870397     Document Type: Article

References (27)

1. Berti M, Casati A, Fanelli G, Albertin A, Palmisano S, Danelli G et al. 0.2% ropivacaine with or without fentanyl for patient-controlled epidural analgesia after major abdominal surgery: a double-blind study. J Clin Anesth 2000; 12: 292-297
2. Paech MJ, Pavy TJ, Orlikowski CE, Lim W, Evans SF. Postoperative epidural infusion: a randomized, double-blind, dose-finding trial of clonidine in combination with bupivacaine and fentanyl. Anesth Analg 1997; 84: 1323-1328
3. Jeffs SA, Hall JE, Morris S. Comparison of morphine alone with morphine plus clonidine for postoperative patient-controlled analgesia. Br J Anaesth 2002; 89: 424-427
4. Rawal N. Epidural and spinal agents for postoperative analgesia. Surg Clin North Am 1999; 79: 313-344
5. Motsch J, Graber E, Ludwig K. Addition of clonidine enhances postoperative analgesia from epidural morphine: A double-blind study. Anesthesiology 1990; 73: 1067-1073
6. Mikawa K, Nishina K, Maekawa N, Asano M, Obara H. Oral clonidine premedication reduces vomiting in children after strabismus surgery. Can J Anaesth 1995; 42: 977-981
7. Park J, Forrest J, Kolesar R, Bhola D, Beattie S, Chu C. Oral clonidine reduces postoperative PCA morphine requirements. Can J Anaesth 1996; 43: 900-906
8. Egan KJ, Ready LB. Patient satisfaction with intravenous PCA or epidural morphine. Can J Anaesth 1994; 41: 6-11
9. Aldrete JA, Kroulik D. A postanesthetic recovery score. Anesth Analg 1970; 49: 924-934
10. Ramsay M, Savege T, Simpson B, Goodwin R. Controlled sedation with Alphaxalone-Alphadolone. Br Med J 1974; 22: 656-659
11. Scott DA, Chamley DM, Mooney PH, Deam RK, Mark AH, Hagloff B. Epidural ropivacaine infusion for postoperative analgesia after major lower abdominal surgery - a dose finding study. Anesth Analg 1995; 81: 982-986
12. Flisberg P, Rudin A, Linner R. Pain relief and safety after major surgery. A prospective study of epidural and intravenous analgesia in 2696 patients. Acta Anaesthesiol Scand 2003; 47: 457-465
13. Rimaitis K, Marchertiene I, Pavalkis D. Comparison of two different methods of analgesia. Postoperative course after colorectal cancer surgery. Medicina 2003; 39: 129-137
14. Egbert AM, Parks LH, Short LM, Burnett ML Randomized trial of posterior patient-controlled analgesia vs. intramuscular narcotics in frail elderly men. Arch Intern Med 1990; 150: 1897-1903
15. Standl T, Burmeister M, Ohnesorge H, Wilhelm S, Striepke M, Gottschalk A et al. Patient-controlled epidural analgesia reduces analgesic requirements compared to continuous epidural infusion after major abdominal surgery. Can J Anaesth 2003; 50: 258-264
16. Rockemann MG, Seeling W, Goertz AW. Effectiveness, side effects and costs of postoperative pain therapy: intravenous and epidural patient-controlled analgesia. Anasthesiol Intensivmed Notfallmed Schmerzther 1997; 32: 414-419
17. Mahon SV, Berry PD, Jackson M, Russell GN, Pennefather SH. Thoracic epidural infusions for post-thoracotomy pain: a comparison of fentanyl-bupivacaine mixtures vs. fentanyl alone. Anaesthesia 1999; 54: 641-646
18. Cooper DW, Ryall DM, McHardy FE, Lindsay SL, Eldabe SS. Patient-controlled extradural analgesia with bupivacaine, fentanyl or a mixture of both, after caesarean section. Br J Anaesth 1996; 76: 611-615
19. Silvasti M, Pitkanen M. Continuous epidural analgesia with bupivacaine-fentanyl versus patient-controlled analgesia with i. v. morphine for postoperative pain relief after knee ligament surgery. Acta Anaesthesiol Scand 2000; 44: 37-42
20. Vallejo MC, Edwards RP, Shannon KT, Kaul B, Finegold H, Ramanathan S, Morrison HL et al. Improved bowel function after gynecological surgery with epidural bupivacaine-fentanyl than bupivacaine-morphine infusion. Can J Anaesth 2000; 47: 406-411
21. Nakayama M, Ichinose H, Nakabayashi K, Satoh O, Yamamoto S, Namiki A. Analgesic effect of epidural neostigmine after abdominal hysterectomy. J Clin Anesth 2001; 13: 86-89
22. Kirdemir P, Ozkocak I, Demir T, Gogus N. Comparison of postoperative analgesic effects of preemptively used epidural ketamine and neostigmine. J Clin Anesth 2000; 12: 543-548
23. Rostaing S, Bonnet F, Levron JC, Vodinh J, Pluskwa F, Saada M. Effect of epidural clonidine on analgesia and pharmacokinetics of epidural fentanyl in postoperative patients. Anesthesiology 1991; 75: 420-425
24. Delaunay L, Leppert C, Dechaubry V, Levron JC, Liu N, Bonnet F. Epidural clonidine decreases postoperative requirements for epidural fentanyl. Regional Anesthesia 1993; 18: 176-180
25. 2-adrenoceptors. Anaesth Pharmacol Rev 1993; 1: 221-232
26. De Vos H, Bricca G, de Keyser J, de Backer JP, Bousquet P, Vauquelin G. Imidazoline receptors, non-adrenergic idazoxan binding sites and alpha 2-adrenoceptors in the human central nervous system. Neuroscience 1994; 59: 589-598
27. Klimscha W, Chiari A, Krafft P, Plattner O, Tasslimi R, Mayer N et al. Hemodynamic and analgesic effects of clonidine added repetitively to continuous epidural and spinal blocks. Anesth Analg 1995; 80: 322-327